RSC - Chem. Soc. Rev. latest articles

The design and development of glucose probes for sensing and imaging within biological systems

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D3CS00795B, Review Article

Open Access

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Hao Wang, Chunfang Li, Fangyuan Zhang, Benjamin Kersch-Hunt, Jordan E. Gardiner, Lijuan Ren, Ying Li, Simon E. Lewis, Yanling Mu, Qingqiang Yao, Luling Wu, Robin R. Groleau, Wenhao Zhai, Zhen Liu, Tony D. James, Eric V. Anslyn, Kai Wang
Glucose and its homeostasis are crucial to biological regulation, making the development of probes for glucose sensing and imaging a long-standing priority in biological and chemical research.
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Various energy-driven high-value-added oxidation reactions in CO2 reduction systems

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS00941C, Tutorial Review

Jinyu Ding, Peijin Du, Mengqian Li, Dongpo He, Qinyuan Hu, Qingxia Chen, Xingchen Jiao, Yi Xie
We summarize a timely and in-depth survey on the development of high-value alternative oxidation reactions to the OER in CO₂ reduction, including photocatalytic, electrocatalytic and multi-energy-driven catalytic CO₂ reduction.
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Thermodynamics of metal–organic frameworks: from fundamentals to advanced applications

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D6CS00060F, Review Article

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Grace C. Thaggard, Danielle N. Smith, Buddhima K. P. Maldeni Kankanamalage, Serena M. Jentz, Natalia B. Shustova
The first overview of MOF thermodynamics is presented with respect to current applications, addressing global challenges.
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Catalytic asymmetric [4+2] cycloadditions of unsaturated hydrocarbons by transition metal catalysis and photocatalysis

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS01218J, Review Article

Open Access

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Jun-Xiong He, Quan Cai
This review highlights recent progress in asymmetric [4+2] cycloadditions of alkenes, alkynes, and allenes by transition-metal catalysis and photocatalysis beyond the conventional Diels–Alder reaction.
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Electrocatalytic amine dehydrogenation as a green route to nitriles: precise construction of efficient catalysts and mechanism

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS01445J, Tutorial Review

Long Chen, Wen-Ping Zhang, Hao Tan, Yu-Ping Zhang, Shuo Sun, Yan-Cheng Zhu, Zhao-Hua Yin, Hong Liu, Jian-Jun Wang
This review outlines nitrile synthesis methods, highlighting recent progress in electrocatalytic amine dehydrogenation to nitriles, with a focus on catalyst design, mechanistic understanding, system optimization, key challenges and future prospects.
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Emerging deposition–dissolution chemistry for next-generation metal-based hybrid flow batteries: progress and perspectives

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS01418B, Review Article

Jie Wei, Jingjie Sun, Sijia Bai, Liuxin Ding, Pengbo Zhang, Yixing Wang, Yuzhu Liu, Kang Huang, Zhong Jin, Zhi Xu
This review provides a comprehensive analysis of the family of metal-based hybrid flow batteries based on deposition–dissolution chemistry, including fundamental principles, advancements in core components, and future research directions.
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Advanced high-entropy materials for fuel cells and water electrolysis

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS01274K, Review Article

Minyuan Liu, Xiaoyan Luo, Guoqing Wang, Gebrehiwot Gebreslassie, Halefom G. Desta, Jianjian Zhang, Bin Lin, Wei Yan, Jiujun Zhang
High-entropy materials (HEMs) represent a paradigm shift in developing efficient components of proton exchange membrane fuel cells/water electrolysis and solid oxide fuel cells/water electrolysis for hydrogen energy conversion and storage.
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Advances in intelligent multi-mode lateral flow assays: from multi-metallic nanomaterials to smart analytical integration

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS00963D, Review Article

Open Access

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Xinyi Liang, Hayoung Kim, Thanh Mien Nguyen, Kun Wang, Chengcheng Li, Seunghyun Lee, Jingbin Zeng, Jaebum Choo
This review highlights intelligent, multi-metallic nanoparticle-based LFAs integrated with AI. It outlines their potential for data-driven, personalised point-of-care diagnostics.
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Recent advances in the strain-release driven reactions of bicyclobutanes: an emerging landscape in organic synthesis

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D6CS00010J, Tutorial Review

Shiksha Deswal, Rohan Chandra Das, Akkattu T. Biju
This tutorial review provides an overview of the important structural features and reactivity modes of BCBs and delves deep into the recent advances in BCB chemistry for the synthesis of bicyclic scaffolds and functionalized cyclobutanes.
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Dynamic interfaces in metal–organic frameworks

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS01236H, Review Article

Yuanjie Cao, Reza Abazari, Qipeng Li, Jinjie Qian
This review deconstructs the dynamic interfaces in MOFs across (i) SBU, (ii) ligand, and (iii) framework interfaces. These interfacial insights establish a structure–dynamics–function paradigm for the design of multifunctional MOFs.
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Computational mechanisms of spin-influenced organic reactions catalyzed by 3d iron-group metals

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS01430A, Review Article

Hongdan Zhu, Tengyue Ma, Guorong Li, Zicong Wang, Junjie Li, Xinyuan Wang, Qian Peng
This review provides computational insights into the spin-influenced mechanisms of C–H bond activation and alkene transformations catalyzed by mono- and binuclear 3d iron-group metal complexes.
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Catalytic strategies for post-translational modifications regulating protein higher-order structure and properties

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D6CS00107F, Tutorial Review

Open Access

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Yuki Yamanashi, Motomu Kanai
Post-translational modifications (PTMs) are chemical switches modulating protein higher-order structures. This Tutorial Review surveys biotic and abiotic catalysis for PTM control, enabling mechanistic understanding and therapeutic applications.
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Squaraine dyes for biophotonics: sensing, imaging and theranostics

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS01375E, Review Article

Open Access

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Sivaramapanicker Sreejith, Chodoparambil Sanjay, Balaraman Vedhanarayanan, Ayyappanpillai Ajayaghosh
In this review we discuss recent advances in the design and application of squaraine dyes as molecular probes across diverse biophotonic platforms. We highlight emerging strategies that leverage their tunable optical features and versatility.
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Amino acid-based biomaterials for modulation of cell behaviors: from mechanisms to biomedical applications

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS01504A, Review Article

Mingyue Liu, Jinjin Chen, Hongjie Li, Yulong Ma, Qingyang Xiao, Jianxun Ding, Jinghong Li, Xuesi Chen
Amino acid-based biomaterials modulate cell behaviors through various chemical and physical mechanisms, gathering increased attention for their advanced potential in biomedical fields.
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Advances in heterochromophoric perylene bisimide self-assemblies towards supramolecular electronics

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS01401H, Review Article

Vidushi Gupta, Samaresh Samanta, Sanchita Sengupta
Perylene bisimide (PBI) dyes owing to their exceptional photophysical features are well-suited for supramolecular electronics. Heterochromophoric PBI assemblies in solution are discussed, focussing on their optical and electronic applications.
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Bridging the gap: gradient scaffolds as bioinstructive platforms for peripheral nerve repair

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS00738K, Tutorial Review

Jie Gao, Feng Xiong, Zhichao Yang, Xilin Ye, Ke Ma, Biyin Shi, Zihao Li, Kaixin Long, Zhengwei You, Liqun Zhang, Huiyu Liu, Jiajia Xue
This tutorial review summarizes gradient scaffold design for peripheral nerve repair from a materials and chemical perspective, linking fabrication strategies to gradient architecture and regulation of cellular behavior and nerve regeneration.
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Emissive organic crystals and device applications

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS01429H, Review Article

Shuai Zhao, Xue-Dong Wang, Hongbing Fu
Emissive organic crystals bridge superior crystalline order with efficient light emission opening new pathways for integrated photonic and optoelectronic devices.
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Deciphering the interaction patterns of intermediates on single atom catalysts during electrocatalytic CO2 conversion reactions

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS00621J, Review Article

Dongfang Li, Xiaobo Zheng, Yufei Zhao, Jinqiang Zhang, Guoxiu Wang
This review presents a unified framework linking coordination in single atom catalysts to the active sites. By classifying intermediate binding patterns, we show how coordination engineering steers CO₂ conversion pathways toward different products.
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Correction: A practical guide to pulsed laser deposition

Chem. Soc. Rev., 2026, 55,3724-3725
DOI: 10.1039/D6CS90021F, Correction

Open Access

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Nick A. Shepelin, Zahra P. Tehrani, Natacha Ohannessian, Christof W. Schneider, Daniele Pergolesi, Thomas Lippert
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The edge of halide perovskites: surfaces and interfaces drive solar efficiency and stability

Chem. Soc. Rev., 2026, 55,3029-3060
DOI: 10.1039/D5CS00636H, Tutorial Review

Diana K. LaFollette, Kunal Datta, Juan Tirado, Michel De Keersmaecker, Erin L. Ratcliff, Juan-Pablo Correa-Baena
Halide perovskites are promising for next-generation optoelectronic applications, but further efficiency gains are limited by interfaces. This review discusses key interfacial roles, materials design strategies, and advances in characterization.
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Formation of active sites in copper-exchanged zeolites for the direct methane-to-methanol conversion

Chem. Soc. Rev., 2026, 55,3078-3138
DOI: 10.1039/D5CS00747J, Review Article

Open Access

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Jörg W. A. Fischer, Andreas Brenig, Johannes Wieser, Jeroen A. van Bokhoven, Vitaly L. Sushkevich
This review outlines current insights into the formation of Cu(II)-oxo species in Cu-exchanged zeolites using various oxidants for methane-to-methanol conversion. It reveals misconceptions and knowledge gaps and proposes strategies to address them.
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Heteroatom doping in carbon macrocycles for advanced synthesis and applications

Chem. Soc. Rev., 2026, 55,3687-3723
DOI: 10.1039/D5CS01268F, Review Article

Open Access

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Chao Liu, Shuangyi Li, Xin Chen, Tonglin Yang, Ying Wei, Linghai Xie, Erik V. Van der Eycken, Wei Huang
Synthesis of heteroatom-doped (N-, O-, S-, N,O-, and N,S-doped) macrocycles and their versatile applications in host–guest chemistry, sensing, catalysis, and optoelectronic devices such as OLEDs, OFETs, and OPVs are discussed.
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Heterogeneous catalytic deuteration using D2O and advances in the application of deuterium labelling

Chem. Soc. Rev., 2026, 55,3645-3686
DOI: 10.1039/D5CS00647C, Review Article

Faxiang Bu, Feiyu Qiu, Yuan Gao, Yuqi Deng, Aiwen Lei, Wu Li
This review highlights recent advances in heterogeneous catalytic deuteration using D₂O and emerging applications of deuterium labelling, including deuterium metabolic imaging, deuterated luminescent materials, and quantitative mass spectrometry.
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Artificial intelligence and machine learning for plasmonic and surface-enhanced sensing

Chem. Soc. Rev., 2026, 55,3599-3644
DOI: 10.1039/D5CS01522G, Review Article

Open Access

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Ailsa Geddis, Hannah Williams, Saba Bashir, Jason Malenfant, Caroline Dubois, Louis Hamlet, Jean-François Masson
Plasmonic sensing is a vibrant field where the optical properties of surface plasmons and artificial intelligence/machine learning are exploited to create analytical sensors for biomedical, environmental and food safety applications, among others.
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Luminescence in macrocyclic supramolecular systems

Chem. Soc. Rev., 2026, 55,3188-3235
DOI: 10.1039/D5CS01550B, Review Article

Ying Han, Yu-Jie Long, Xiao-Ni Han, Chuan-Feng Chen
This review systematically summarizes the design and construction strategies of new MSLSs according to their luminescence mechanism, and highlights their applications in chemical sensing, bioimaging, information anti-counterfeiting and photocatalysis.
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Recent progress in transition-metal-catalysed intermolecular saturated C(sp3)–N(sp3) bond formation reactions

Chem. Soc. Rev., 2026, 55,3469-3598
DOI: 10.1039/D5CS00923E, Review Article

Jun-Song Jia, Muneer-ul-Shafi Bhat, Lan Tian, Hao-Ran Zhang, Yu-Long Li, Qiong Yu, Wei Shu
This review provides an overview on recent developments in transition-metal-catalysed intermolecular saturated C(sp³)–N(sp³) bond-forming reactions. Moreover, limitations and perspectives on emerging opportunities in this area are also discussed.
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Hydrogels for robust thermal management: mechanism and applications

Chem. Soc. Rev., 2026, 55,3432-3468
DOI: 10.1039/D5CS01351H, Review Article

Xueyan Hu, Ling Liu, Jin Wang
This review highlights design strategies, applications, and future directions of hydrogels for next-generation thermal management.
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Molecular innovations in nanofiltration via interfacial polymerization: from monomer design to membrane performance

Chem. Soc. Rev., 2026, 55,3380-3431
DOI: 10.1039/D5CS00787A, Review Article

Open Access

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Wenxing Cheng, Qipeng Zhao, Huaqiang Chu, Xuefei Zhou, Yalei Zhang, Tai-Shung Chung
This study reviews advances in novel monomers, summarizes fabrication strategies for nanofiltration membranes, analyzes structure–performance relationships and underlying synergistic mechanisms, proposes improvements and future directions.
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Pushing ionic thermoelectrics toward power supply applications: origins, advances, challenges, and future directions

Chem. Soc. Rev., 2026, 55,3303-3379
DOI: 10.1039/D5CS01175B, Review Article

Menghan Shang, Tingting Sun, Liuqi Cao, Huiru Zhao, Lianjun Wang, Wan Jiang
Four representative paradigms of ionic thermoelectrics are systematically discussed, from basic theories, operating mechanisms, and material design to device engineering, aiming to guide the rational development of power supply applications.
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Innovative approaches to the synthesis of five-membered heteroaromatics with emerging synthetic methodologies

Chem. Soc. Rev., 2026, 55,3236-3302
DOI: 10.1039/D5CS01300C, Review Article

Open Access

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Yu Zhang, Qiannan Li, Zhimin Hu, Zhiyong Leng, Wei-dong Zhang, Shoubhik Das
A conceptual overview and discussions are presented to showcase the synthesis of five-membered heteroaromatics and related drugs using emerging toolboxes (photochemical synthesis, electrocatalysis and biocatalysis).
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Molecular fluorophore dimerization: a new paradigm for precision phototheranostics

Chem. Soc. Rev., 2026, 55,3139-3187
DOI: 10.1039/D5CS01306B, Review Article

Open Access

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Hui Bian, Dandan Ma, Yahui Chen, Jeongyeon Hong, Yi Nan, Hai Xu, Myung Hwa Kim, Xiaoqiang Chen, Xiaojun Peng, Juyoung Yoon
This review maps how dimer architectures regulate photophysical processes and biophysical behaviors, offering a unifying framework for the rational design of next-generation phototheranostics.
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Bioinspired thermal management fibers and textiles

Chem. Soc. Rev., 2026, 55,3005-3028
DOI: 10.1039/D5CS01328C, Tutorial Review

Mingrui Wu, Xuanhao Lin, Weiwei Gao, Hao Bai
This tutorial review introduces the fundamental heat transfer principles of body, the natural thermal management mechanisms, and the emerging bioinspired fibers and textiles, offering novel strategies for fabricating thermal management materials.
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Charging molecular nanographenes with electrons through chemical reduction

Chem. Soc. Rev., 2026, 55,3061-3077
DOI: 10.1039/D5CS01377A, Review Article

Yikun Zhu, Marina A. Petrukhina
Chemical reduction coupled with X-ray crystallographic and spectroscopic analyses reveals the electron accepting abilities of molecular nanographenes with various topological features, further supporting their advanced energy-storage applications.
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Cluster-based materials: design and applications

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS00663E, Review Article

Open Access

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Hong Fang, Qiang Sun, Puru Jena
Polyatomic clusters and their derived materials constitute an interdisciplinary field with broad applications, bridging chemistry, physics, biomedicines, and materials sciences.
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Micro–nano surface engineering and property modulation: insights from black silicon for advanced material applications

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS01448D, Review Article

Junling Lv, Lihong Jiang, Xinlin Liu, Gaojie Li, Mingrui Qian, Mingxin Tang, Xinao Cheng, Lan Lu, XiaRong Ren, Xueling Zhang, Haiyang Zou, Zhong Lin Wang
Micro–nanotechnology tailors semiconductor properties. Using black silicon as a model, this review highlights micro/nano surface morphology and surface states, revealing structure–property relationships for diverse applications.
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Functional tetrapodal zinc oxide: from synthesis and multiphysics to advanced applications

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS00594A, Review Article

Open Access

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Mozaffar Abdollahifar, Erik Greve, Jonas Lumma, Rainer Adelung
This review synthesizes recent developments in tetrapodal ZnO, including synthesis, properties, and applications. It highlights tetrapodal ZnO as a microscopic building unit bridging the design gap between nanoscopic and macroscopic 3D assemblies.
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The long road to outdoor stability: real-world challenges for controlling perovskite materials for solar cells

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS01085C, Review Article

Open Access

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Juan José Patiño López, Kelly G. Rivera Botia, Kevin Ballestas, Esteban Velilla, Juan Felipe Montoya, Franklin Jaramillo, Daniel Ramirez
Real-world performance of perovskite solar cells: chemical control of materials for highly stable devices under outdoor evaluations.
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Multicolour luminescence phenomena of vibration-induced emission

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D5CS01495F, Review Article

Xin Jin, Xuwen Sun, Yuting Zou, Zhiyun Zhang, He Tian
This review summarizes vibration-induced emission (VIE) in sterically hindered dihydrophenazines. It details how structural vibrations enable multi-color emission, covering design principles, mechanisms, and applications in sensing materials.
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Correction: Functionalization of o-carboranes via carboryne intermediates

Chem. Soc. Rev., 2026, Advance Article
DOI: 10.1039/D6CS90026G, Correction

Open Access

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Zaozao Qiu, Zuowei Xie
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