RSC - Food Funct. latest articles

A fructo-oligosaccharide and sea buckthorn complex ameliorates glucose and lipid metabolism in type 2 diabetic (T2DM) rats via metabolic and anti-inflammatory pathways

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO04996B, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Ling Chen, Hualin Liu, Yanwu Chen, Qianya Xiao, Zijin Huang, Ziying Li, Xiaofei Zhang, Xueying Fan, Meichen Xiao, Xiaomin Li, Yuan Yao Chen
This study investigated the effects and underlying mechanisms of a fructo-oligosaccharide (FOS) and sea buckthorn complex (FS) on blood glucose and lipid metabolism in type 2 diabetic mellitus (T2DM) rats.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Plant-protein Stabilized Emulsions as β-carotene Delivery Systems: Colloidal Stability and Behaviour during in vitro Digestion Conditions

Food Funct., 2026, Accepted Manuscript
DOI: 10.1039/D5FO05533D, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Mohsen Ramezani, Marga Amengual Ramon, Laura Salvia-Trujillo, Olga Martín-Belloso
Plant proteins offer a promising clean-label alternative to synthetic surfactants, but their emulsifying properties are strongly dictated by pH. This study investigates how pH (3.0 and 7.0) governs the physicochemical...
The content of this RSS Feed (c) The Royal Society of Chemistry

Lithocarpus litseifolius leaf extract and its flavonoids alleviate hyperuricemia via TLR2/PI3K/NF-κ B pathway inhibition and gut microbiota modulation

Food Funct., 2026, Accepted Manuscript
DOI: 10.1039/D5FO05398F, Paper

Shaoyi Cai, Yuanyuan Chen, Tao Luo, Guangqiang Ma, Yu Zhong, Ailan Wu, Shuhong Peng, Chengdong Liao, Hua Zhang, Changhua Zhang, Lan Cao
Lithocarpus litseifolius (Hance) Chun (Lithocarpus polystachyus rehd.) is a medicinal and edible plant. This study investigated the therapeutic effects of Lithocarpus litseifolius (LLL) leaf extract and its five key flavonoids...
The content of this RSS Feed (c) The Royal Society of Chemistry

Microbial–enzymatic co-fermentation enhanced the beneficial effects of highland barley bran on preventing metabolic disorders and gut microbiota dysbiosis induced by a high-fat diet in obese mice

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00739B, Paper

Xuewei Feng, Muyu Feng, Yajun Cui, Junchao Wu, Siqi Zhang, Ting Bai, Yuhong Zhang, Fang Zhong, Yang Yao, Sumei Zhou, Dianzhi Hou
Microbial–enzymatic co-fermentation of HBB elevated its free phenolic content. The resulting product alleviated obesity and metabolic disorders in HFD-fed mice by modulating hepatic lipid synthesis genes and restoring the gut microbiota.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Milk exosomes attenuate OVA-induced food allergy by regulating the Th1/Th2 balance and remodeling the gut microbiota

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00469E, Paper

Siqi Fu, Chao Zhang, Yan Liu, Xin Ma, Ruofan Xie, Hongbing Chen, Xin Li
M-Exo was extracted by ultracentrifugation and a model of daily intervention of M-Exo in OVA allergic mice was established to study the immune regulatory effect of M-Exo on food allergy in mice.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

The dietary index for gut microbiota, genetically predicted gut microbiome, and the risk of chronic kidney disease: a cohort study

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00453A, Paper

Zheng Ma, Yixiao Zhang, Honghao Yang, Gang Zheng, Liuxin Li, Ruiyao Zhang, Xiang Ji, Chao Ji, Yang Xia, Yuhong Zhao
A higher dietary index for gut microbiota (DI-GM) is associated with a lower risk of incident chronic kidney disease in a large prospective cohort, highlighting the role of diet–microbiome interactions in kidney health.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Modulation and adaptation of gut microbial metabolic functions under probiotic and postbiotic treatment using a novel in vitro anaerobic pseudo-colon system

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO04976H, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Nehal Batra, Prangya Ranjan Rout, Priyankar Dey
Probiotic and postbiotic compounds found in food influence gut microbiota to attenuate chronic metabolic diseases; however, the underlying mechanisms are not yet fully understood.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Acid hydrolysis of jaboticaba (Myrciaria jaboticaba) peel and seed powder increases urolithin excretion in a cross-over clinical trial with normoweight subjects

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO04952K, Paper

Rafael Bizarelo, Kim Ohanna Pimenta Inada, Daniel Perrone, Mariana Monteiro
This clinical trial with 23 young adults compared urolithin excretion after intake of non-hydrolyzed and hydrolyzed jaboticaba peel and seeds. Acid hydrolysis increased urinary urolithins excretion by 50% without altering the total excretion rate.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Anti-inflammatory Effect of Gallic Acid on Chronic Bacterial Prostatitis: Involving Target Tissue Distribution

Food Funct., 2026, Accepted Manuscript
DOI: 10.1039/D5FO05256D, Paper

Yuhong Huang, Xiaomei Liu, Shengjie Kong, Qian Yang, Luyao Ma, Xurui Zuo, Xinyue Liu, Ziqiang Li, Chunxiao Lv
Gallic acid (GA), also known as 3,4,5-trihydroxybenzoic acid, is a polyphenolic bioactive component in pomegranates, grapes, tea leaves, and gallnuts. This study employed LC-MS/MS to systematically analyze the pharmacokinetic and...
The content of this RSS Feed (c) The Royal Society of Chemistry

Taurine mitigates bisphenol A-induced maternal–fetal oxidative stress and improves fetal weight by regulating Nrf2-Keap1 pathway, gut microbiota and bile acid metabolism

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00521G, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Lei Xu, Chenggang Yin, Yuyang Fan, Jiaqi Yang, Dongxu Ming, Yanpin Li, Wenjuan Sun, Xilong Li, Yu Pi
Taurine mitigates bisphenol A (BPA) exposure-induced disruption of the maternal–fetal environment, resulting in fetal growth restriction and tissue damage.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Yeast protein improves musculoskeletal and systemic functions in mice

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO01039C, Paper

Xialei Liu, Jin Luo, Yongzhao Bi, Chung-Ying Andy Lee, Shuai Liu, Yuan Ma, Shihao Sun, Lili Zhang, Jialiang Xu
Yeast protein (YP) is rich in high-quality protein and a variety of bioactive compounds and has been shown to confer beneficial effects on overall health.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Plasma carotenoids and (poly)phenols in people living with an ileostomy: associations with dietary intake

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00497K, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Niamh Magee, Brian Óg Murphy, Gema Pereira-Caro, Salud Caceres-Jimenez, Mary Slevin, Roger Lawther, Gloria O'Connor, James Davis, L. Kirsty Pourshahidi, Alan Crozier, Chris I. R. Gill
Individuals with an ileostomy (ileostomists) face unique physiological and dietary challenges that may impact on the bioavailability of phytochemicals, including carotenoids and (poly)phenols.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Plant proteins for human health: current status and future needs

Food Funct., 2026, Accepted Manuscript
DOI: 10.1039/D6FO00549G, Review Article

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Kun Gao, Shiyu Zhou, Jiajia Rao, Bingcan Chen
Plant based protein consumption is increasingly recognized for its therapeutic potential in managing metabolic health and preventing chronic diseases. This review provides a comprehensive analysis of the physiological impacts of...
The content of this RSS Feed (c) The Royal Society of Chemistry

The role of gut microbiota in shaping and modulating dietary preferences in neurological diseases: implications for microbiota-targeted interventions

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO02826D, Review Article

Tingting Hou, Zhixing Peng, Yonglin Chen, Yanqing Feng, Xiaohui Hou, Yu-Heng Mao
The dietary preferences of patients with neurological disorders interact with the brain through different pathways of the gut-brain axis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Secoisolariciresinol diglucoside resolves systemic and skin inflammation in psoriatic mice by ameliorating the gut microbiome and modulating immune responses

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO04965B, Paper

Bao-Juan Yuan, Yu-Hui Wang, Jin-Ru Lai, Liang Liu, Jia-Wei Zhang, Hong-Da Tian, Randal N. Johnston, Gui-Rong Liu, Shu-Lin Liu
The lignans (SDG and its metabolite ENL) have potent effects to resolve psoriatic inflammation and alleviate skin pathology by redressing the gut dysbiosis and modulating immune functions.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Urinary track health benefits and phytochemical characterization based on a narrative review on cranberry and its innovative formulation in phospholipids

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO05249A, Review Article

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Francesco Scaglione
Cranberry is rich in nutritional components and numerous bioactive compounds with properties useful in a variety of physiological and clinical conditions.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Investigating the impact of astaxanthin yogurt on gut microbiota and microbiota-mediated astaxanthin conversion using the SHIME® model

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO04878H, Paper

Wenmei Zhang, Houyang Sun, Jinyu Zhou, Peixu Cong, Qingjuan Tang
This study aimed to assess the long-term effects of astaxanthin yogurt on the human gut microbiota using the Simulator of Human Intestinal Microbial Ecosystem (SHIME®).
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Dietary (poly)phenols, the gut-brain axis, and menopause: a perspective on an overlooked biological crossroad

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00429F, Review Article

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

María García-Nicolás, María Paula Jarrín-Orozco, María Romo-Vaquero, María Elena Martínez-Nortes, María Ángeles Ávila-Gálvez, Juan Carlos Espín
Polyphenols and gut-derived metabolites modulate SCFAs, indoles, TMA, and neuroactive pathways, thereby shaping gut-brain communication in postmenopausal women facing hormonal decline, inflammation, metabolic changes, and polypharmacy.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Ameliorative effects of red-fleshed apple flavonoid extracts (RAFEs) on high-fat diet-induced metabolic dysfunction-associated steatotic liver disease (MASLD) in mice

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO05405B, Paper

Yizhou Chen, Yaqi Dong, Zhaozheng Fan, Shenghui Jiang, Ya Wu, Chengkun Wang, Tongyao Zhu, Zhongkang Wang, Shaoxia Guo, Yugang Zhang, Xiao Liang
Red-fleshed apple flavonoid extracts (RAFEs) rich in isorhamnetin glycosides alleviate high-fat diet-induced MASLD by suppressing hepatic inflammation, oxidative stress, and dyslipidaemia while restoring gut microbiota homeostasis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Effects of different galactans on DSS-induced colitis and the gut microbiota

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00058D, Paper

Xuefei Wei, Chunhua Chen, Shaoping Nie
Nonlinear galactans can significantly alleviate DSS-induced colitis symptoms in mice, and upregulate the abundance of beneficial bacteria. Linear galactans showed no significant alleviative effects, and the gut microbiota remained disordered.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Oleic and omega-3 fatty acids buffer neuroinflammation in a scopolamine model with Alzheimer’s-like features via target-level interactions

Food Funct., 2026, Accepted Manuscript
DOI: 10.1039/D6FO00279J, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Marlua Albertuni, Maria Torrecillas-Lopez, Teresa Gonzalez-de la Rosa, Luna Barrera-Chamorro, Elvira Marquez-Paradas, Jose L. del-Rio-Vazquez, Maria D Navarro-Hortal, Carmen Claro, Sergio Montserrat-de la Paz
Diet quality, beyond total fat, may shape brain immune tone in Alzheimer’s-relevant contexts. We examined whether the fatty acid profile and food matrix of high-fat diets (HFD) modulate hippocampal neuroinflammation...
The content of this RSS Feed (c) The Royal Society of Chemistry

Multi-omics reveals gut microbiome- and metabolome-specific responses to sugar alcohols

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00282J, Paper

Mengling Liu, Zhandong Yang, Boyu Liu, Hongbo Cheng, Jiannan Qin, Pingjun Zhang, Tingfan Tang, Fei Peng, Jiguo Yang, Ping Wei, Huihui Su
The impacts of sugar alcohols (SA) utilized as low-calorie sweeteners on the gut microbiome and metabolome remain undefined.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Effect of Capsicum annuum leaf extract addition timing on yogurt bioactivity, digestibility, and cellular antioxidant defence

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00042H, Paper

Ajibola Nihmot Ibrahim, Ning Xu, Suxia Shen, Zhaotian Yang, Lin Zeng, Yan Zhang
The timing of Capsicum annuum leaf extract addition alters yogurt functionality: pre-fermentation addition boosts antioxidant stability and cellular antioxidant defence; post-fermentation addition improves protein digestibility and enzyme inhibition.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Fucoidan Alleviates Kidney Fibrosis by Shaping the Gut Microbiota and Modulating Tryptophan Metabolism

Food Funct., 2026, Accepted Manuscript
DOI: 10.1039/D6FO00785F, Paper

Ying Zhang, Jinxin Li, Wanting Chen, Fengxia Qin, Yuan Tian, Zunjian Zhang, Fengguo Xu, Pei Zhang
Chronic kidney disease (CKD) is a major global health burden, with renal fibrosis as the key pathological driver of disease progression. Fucoidan (FPS) is a sulfated polysaccharide from brown algae...
The content of this RSS Feed (c) The Royal Society of Chemistry

Diosmetin's impact on epileptic seizures: a study on inflammatory pathways and neuronal health

Food Funct., 2026, Accepted Manuscript
DOI: 10.1039/D5FO04609B, Paper

Yahong Cheng, Jinhu Zhang, Xu Cao, Xinyi Li, Yi Ding, Yiyu Guo, Qianqian Geng, Jiayi Qiu, Jing Rao
This study investigated the anti-seizure potential of diosmetin (DM), a naturally occurring active compound, and explored its molecular mechanisms. A pentetrazole (PTZ)-induced chemical kindling mouse model was employed to assess...
The content of this RSS Feed (c) The Royal Society of Chemistry

Polyphenols in gut barrier function across diverse natural sources: mechanisms and comparative insights in berry and seaweed-derived compounds

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO05231A, Review Article

Scott D. Smid
Dietary polyphenols protect human intestinal barrier function via multiple pathways. Via diverse natural sources: from berry flavonoids to seaweed phlorotannins.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Consumption of an anthocyanin-rich extract increases circulating BDNF and BDNF gene expression in healthy subjects consuming a high-fat meal

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00793G, Paper

Wei Zhu, Imani Muhammad, Eleonora Cremonini, Patricia I. Oteiza
Brain-derived neurotrophic factor (BDNF) is a growth factor that has a central role in sustaining brain function.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Effects of a phenolic-rich grape pomace extract on intestinal barrier, gut microbiota, and adipose tissue in high-fat diet–fed mice

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO04667J, Paper

Diahann J. Perdicaro, Victoria Muscia Saez, Valeria V. Costantino, Eleonora Cremonini, Valeria E. Cacciamani, Hatice Duman, Sercan Karav, Steven A. Frese, Marcela A. Vazquez Prieto
Obesity disrupts intestinal barrier integrity and gut microbiota, contributing to endotoxemia and adipose tissue dysfunction. Grape pomace extract attenuates these alterations.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Corn silk extract ameliorates cisplatin-induced cardiac injury by restoring mitochondrial function and suppressing ferroptosis

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00450D, Paper

Qingxuan Yang, Yumo Li, Li Qi, Jianwen Wang, Mengmeng Liu, Jianhao Huang, Mingyang Sun, Yuheng Fu, He Lin, Zhe Lin, Guangfu Lv, Yuchen Wang
Zea mays L., a traditional edible botanical and abundant agricultural by-product, is rich in polyphenols and flavonoids.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lactobacillus reuteri BNCC186563 Ameliorates Lipid Metabolism Disorder in Obese Mice by Activating the PPARα Signaling Pathway

Food Funct., 2026, Accepted Manuscript
DOI: 10.1039/D6FO00358C, Paper

aibei zhu, Wenjuan Shen, Bibi Zainab, Xiaohu Luo, Xiping Wu, Yanan Liu
Obesity is a chronic disease that is now recognized as a global epidemic. Therefore, the need for effective therapeutic options to combat obesity cannot be overemphasized. Here, we demonstrate a...
The content of this RSS Feed (c) The Royal Society of Chemistry

Association of dietary calcium and its food sources with age-related macular degeneration in China: a population-based case-control study

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO04327A, Paper

Hong Jiang, Xiaoyan Wang, Lina Wang, Yahui Fan, Zhaofang Li, Mei Ma, Sijiao Liu, Baoyu Li, Jia Shi, Chao Li, Le Ma, Juan Li, Wei Zhang
Higher dietary calcium was associated with a reduced risk of age-related macular degeneration in a Chinese population with relatively low intake. A similar inverse association was found for dairy-derived calcium, but not for vegetable or legume sources.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Impact of pineapple (Ananas comosus [L.] Merr.) processing under low oxygen conditions using an innovative spiral filter press on juice physical characteristics and phytochemical composition

Food Funct., 2026, Accepted Manuscript
DOI: 10.1039/D5FO05382J, Paper

Patricia Esquivel, Victor M. Jimenez, Vicky Bäumer, Jelena Nagypál, Peter Bach, Claus Patz, Michael Ludwig, Ralf Schweiggert, Christof Björn Steingass
This study compared pineapple (Ananas comosus ‘MD2’) juices produced using either a vacuum-driven spiral filter press (SFP) or a conventional rack-and-cloth press (RCP). To our knowledge, this represents the first...
The content of this RSS Feed (c) The Royal Society of Chemistry

Pine pollen fiber alleviates constipation induced by loperamide in mice: Focus on gastrointestinal motility-related hormones, short-chain fatty acids, and gut microbiota changes

Food Funct., 2026, Accepted Manuscript
DOI: 10.1039/D6FO00700G, Paper

Zhiwei Li, Yong Cheng, Dandan Ma, Liduan Yin, Tong Wang, Zhaojun Wang, Qiuming Chen, Maomao Zeng, J. Chen, Benu Adhikari, Zongping Zheng, Zhiyong He
Constipation, a prevalent gastrointestinal disorder, urgently requires safe and effective intervention strategies. Natural dietary fibers have gained attention for their potential to alleviate constipation through multiple mechanisms. This study investigated...
The content of this RSS Feed (c) The Royal Society of Chemistry

Correction and removal of expression of concern: Musa paradisiaca inflorescence induces human colon cancer cell death by modulating cascades of transcriptional events

Food Funct., 2026, 17,3415-3416
DOI: 10.1039/D6FO90026G, Correction

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Arun K. B., Aravind Madhavan, Reshmitha T. R., Sithara Thomas, P. Nisha
The content of this RSS Feed (c) The Royal Society of Chemistry

Lipase-catalysed acidolysis for enrichment of medium-chain triacylglycerols in virgin coconut oil and its functional properties

Food Funct., 2026, 17,3386-3399
DOI: 10.1039/D5FO04699H, Paper

Mayookha V. P., Bhumika K. P., Raksha Umesh, Nanishankar V. Harohally, Soujanya K. V., Suresh Kumar G.
Lipase-catalysed acidolysis of virgin coconut oil for enrichment of medium-chain triacylglycerols.
The content of this RSS Feed (c) The Royal Society of Chemistry

Effects of infant formula supplied with medium- and long-chain triacylglycerols and sn-2 palmitate on fecal lipid metabolome and microbiota profiles in healthy term infants: a parallel-controlled study

Food Funct., 2026, 17,3091-3098
DOI: 10.1039/D5FO04757A, Communication

Jiahui Yu, Zhengdong Liu, Mengtao Yang, Qianqian Bi, Xuezhen Zhou, Yingzhen Qiu, Xingwang Ye, Wei Wei, Xingguo Wang
Infant formula fortified with MLCT and sn-2 palmitate showed a comparable fecal lipidomics pattern to breast milk. Significant correlations were observed between fecal lipid and beneficial microbiota such as Bifidobacterium.
The content of this RSS Feed (c) The Royal Society of Chemistry

Upcycling walnut (Juglans regia L.) by-products: characterisation of nutritionally relevant bioactive compounds

Food Funct., 2026, 17,3161-3171
DOI: 10.1039/D6FO00494F, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Francesc M. Campins-Machado, Clara Abarca-Rivas, Marina Corrado, Maria Pérez, Anna Vallverdú-Queralt
Underutilised green walnuts, defective walnuts, and walnut shells are rich sources of bioactive compounds with potential for food, nutraceutical, and cosmetic applications.
The content of this RSS Feed (c) The Royal Society of Chemistry

Effects of limonin and nomilin on lipid metabolic homeostasis in hyperlipidemic mice

Food Funct., 2026, 17,3099-3114
DOI: 10.1039/D5FO05534B, Paper

Nan Zhang, Yujia Ou, Tao Hong, Fan He, Zhipeng Li, Yanbing Zhu, Hui Ni, Zedong Jiang, Yang Hu, Mingjing Zheng
The potential of citrus-derived limonoids (limonin and nomilin) in restoring lipid metabolic homeostasis by regulating microbial metabolism.
The content of this RSS Feed (c) The Royal Society of Chemistry

Tryptophan metabolites derived from Lactiplantibacillus plantarum Y42 regulate the AhR/Nrf2/NF-κB axis to ameliorate colitis in mice

Food Funct., 2026, 17,3324-3335
DOI: 10.1039/D5FO04869A, Paper

Xiaoxi Gao, Yanli Liu, Jiang Yu, Guangqing Mu, Yanfeng Tuo
Y42 activated the AhR signaling pathway by metabolizing Trp to produce ILA, IPA, IAA, and IAld, thereby ultimately alleviating colonic inflammation and barrier function damage.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lactobacillus combination alleviates dextran sulfate sodium-induced colitis in Wuzhishan minipigs

Food Funct., 2026, 17,3306-3323
DOI: 10.1039/D4FO04728A, Paper

Xiaozhe Wang, Xiangyu Ma, Xin Zhang, Yang He, Yinfeng Chen, Qingyao Fu, Ying Yang, Xiaomin Yin, Zhenlong Wu
Lactobacillus combination alleviates colitis in minipigs by reducing oxidative stress, suppressing inflammation, enhancing gut barrier function, modulating microbiota, and restoring SCFAs.
The content of this RSS Feed (c) The Royal Society of Chemistry

Prune (dried plum) consumption does not reduce colonic tumor formation but drives beneficial changes in the gut microbiome of rats

Food Funct., 2026, 17,3291-3305
DOI: 10.1039/D5FO03398E, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Minghong Jiang, Andres Gomez, Davis M. Seelig, Daniel D. Gallaher
In rats given a colon carcinogen, prune consumption altered the microbiome and increased large intestinal butyrate, but did not reduce colonic tumor number, challenging the role of butyrate as a chemoprevention agent.
The content of this RSS Feed (c) The Royal Society of Chemistry

The effect of anthocyanins through diet and supplementation on cognitive function in older adults: a multi-centre randomised controlled clinical trial

Food Funct., 2026, 17,3400-3414
DOI: 10.1039/D5FO05366H, Paper

V. do Rosario, K. Chan, E. Lorzadeh, H. Brodaty, K. J. Anstey, K. Kent, S. Roodenrys, V. Bliokas, L. Phillipson, M. E. Francois, M. J. Batterham, T. Cyriac, K. Weston-Green, X. Jiang, J. George, J. Potter, K. E. Charlton
Anthocyanins, a flavonoid subclass present in certain blue, purple and red fruits and vegetables, have potential neuroprotective properties due to their anti-inflammatory, antioxidant, and signalling effects.
The content of this RSS Feed (c) The Royal Society of Chemistry

Genetic determinants of lycopene concentration in subcutaneous adipose tissue: insights into interindividual variability in adult males

Food Funct., 2026, 17,3148-3160
DOI: 10.1039/D5FO05171A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Mark Pretzel Zumaraga, Patrick Borel, Charles Desmarchelier
Lycopene is a carotenoid obtained primarily from tomatoes and tomato-based products.
The content of this RSS Feed (c) The Royal Society of Chemistry

Metabolic and inflammatory effects of oleuropein and olive leaf extract: a systematic review and meta-analysis

Food Funct., 2026, 17,3077-3090
DOI: 10.1039/D5FO04235F, Review Article

Rafaella Câmara Rocha Menezes, Kathleen Kruger Peres, Isabella Rosa da Mata, Simone Morelo Dal Bosco, Juliano Garavaglia, Eliane Dallegrave
Current randomized clinical trials do not support statistically or clinically robust evidence of health benefits from oleuropein or olive leaf extract supplementation.
The content of this RSS Feed (c) The Royal Society of Chemistry

Enhanced dietary monitoring using fecal genomics for childhood malnutrition interventions

Food Funct., 2026, 17,3128-3137
DOI: 10.1039/D5FO02791H, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Ammara Aqeel, Najeeha T. Iqbal, Sanam Iram Soomro, Sheraz Ahmed, Teresa K. McDonald, Olivia Osborne, Sharon Jiang, Nolan Ives, Kazi Ahsan, Fayaz Umrani, Michael J. Barratt, Jeffrey I. Gordon, Syed Asad Ali, Lawrence A. David
Ready-to-use therapeutic and supplementary foods (RUTF/RUSF) are a primary treatment for childhood malnutrition, but measuring intervention compliance is labor intensive and unreliable.
The content of this RSS Feed (c) The Royal Society of Chemistry

Ligilactobacillus salivarius Li01 enhances gut microbiota-derived indole-3-propionic acid to alleviate 5-fluorouracil-induced diarrhea in mice

Food Funct., 2026, 17,3248-3264
DOI: 10.1039/D6FO00050A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Pengyu Yin, Bo Qiu, Lvwan Xu, Siyuan Xie, Shuobo Zhang, Jingyi Zhang, Björn Berglund, Mingfei Yao, Lanjuan Li
Li01 administration alleviated 5-FU-induced diarrhea by mitigating inflammation and oxidative damage, and restoring intestinal barrier. Li01 exerted its benefits by elevating the level of gut microbiota-derived IPA, which activated the PXR.
The content of this RSS Feed (c) The Royal Society of Chemistry

Dual improvement effects of ω-3 on bone loss and liver injury in rats with liver–bone axis damage

Food Funct., 2026, 17,3229-3247
DOI: 10.1039/D6FO00026F, Paper

Jiahui Huang, Long Chen, Haojie Yu, Shishuai Zhou, Jianzhong Guan, Chen Xu
Supplementation with ω-3 polyunsaturated fatty acids can promote the recovery of RCT function in HOD rats, playing a dual role in improving liver function and alleviating bone loss.
The content of this RSS Feed (c) The Royal Society of Chemistry

Functional potential of crackers formulated with an innovative fermented cooked chickpea flour

Food Funct., 2026, 17,3275-3290
DOI: 10.1039/D5FO05351J, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Manuela Flavia Chiacchio, Silvia Tagliamonte, Giuseppe Blaiotta, Angela Pazzanese, Cristina Juan, Ana Juan-García, Paola Vitaglione
Fermented chickpea flour enhances cracker polyphenols, antioxidant activity, and α-amylase/α-glucosidase inhibition, while improving polyphenol bioavailability, supporting the development of healthier snack formulations.
The content of this RSS Feed (c) The Royal Society of Chemistry

Bisdemethoxycurcumin extends lifespan and healthspan in Caenorhabditis elegans via modulation of EGFR-linked signaling pathways

Food Funct., 2026, 17,3212-3228
DOI: 10.1039/D5FO04963F, Paper

Ruidie Shi, Yihan Zhang, Chaoxue Li, Xinyue Li, Chuyue Tu, Chen Sun, Shengnan Liu, Ruikun He, Xumei Zhang
BDMC targets EGFR, activating Ras/Raf/MAPK while inhibiting PI3K/AKT, leading to extended lifespan, improved stress resistance, and reduced senescence in C. elegans.
The content of this RSS Feed (c) The Royal Society of Chemistry

Epigallocatechin-3-gallate ameliorates LPS-induced ARDS by modulating Akkermansia-associated SCFAs metabolism and inhibiting the JAK2/STAT3 candidate signaling pathway

Food Funct., 2026, 17,3186-3211
DOI: 10.1039/D5FO05380C, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Shiming Fan, Guofang Yin, Yan Ren, Xiaoqing Fan, Yuling Liang, Ning Ma, Ying Luo, Yi Deng, Chunmei Zhang, Tian Xiang, Jing Zuo, Jingli Tang, Dan Luo, Xianming Fan
A comprehensive understanding of the mechanisms by which EGCG improves ARDS, offering a theoretical basis and potential targets for ARDS treatment strategies based on the gut–lung axis, with significant clinical translational value.
The content of this RSS Feed (c) The Royal Society of Chemistry

Probiotic cell wall components as emerging postbiotics: structural diversity, immunoregulatory mechanisms, and health applications

Food Funct., 2026, 17,3028-3049
DOI: 10.1039/D6FO00491A, Review Article

Lina Ding, Jiaqi Yin, Jiaqi Liu, Jing Zou, Junwen Liu, Yao Jin, Maolin Tu, Ping Li, Qing Gu, Jiarun Han
Probiotics exert health benefits through multifaceted interactions with the host, and accumulating evidence indicates that many of these effects are mediated by defined cell envelope-derived molecules rather than live bacteria per se.
The content of this RSS Feed (c) The Royal Society of Chemistry

Regular black tea kombucha consumption is associated with improved insulin resistance and increased ADIPOQ expression in adults with obesity: a pre–post clinical trial

Food Funct., 2026, 17,3353-3371
DOI: 10.1039/D5FO02226F, Paper

Mirian Aparecida de Campos Costa, Gabriela Macedo Fraiz, Rodrigo Rezende Cardoso, Alessandra da Silva, Vinícius da Silva Duarte, Carlos Eduardo Soares Gazzinelli Cruz, Evando Geraldo Rodrigues, Maliha W. Shaikh, Ali Keshavarzian, Bruce R. Hamaker, Viviana Corich, Alessio Giacomini, Hércia Stampini Duarte Martino, Josefina Bressan, Frederico Augusto Ribeiro de Barros
Kombucha is a fermented beverage obtained by a Symbiotic Culture of Bacteria and Yeast (SCOBY).
The content of this RSS Feed (c) The Royal Society of Chemistry

Association between mushroom consumption and digit span performance among middle-aged and older community-dwelling Japanese: the NILS-LSA project

Food Funct., 2026, 17,3265-3274
DOI: 10.1039/D5FO04625D, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Shu Zhang, Djibril M. Ba, Yukiko Nishita, Chikako Tange, Junjia Zhu, Rei Otsuka, Joshua Muscat
Regular mushroom consumption may enhance short-term and working memory during aging.
The content of this RSS Feed (c) The Royal Society of Chemistry

Diacylglycerol ameliorates obesity-induced osteoporosis through inhibiting NF-κB pathway mediated osteoclast differentiation

Food Funct., 2026, 17,3138-3147
DOI: 10.1039/D5FO05472A, Paper

Hao Yue, Xiuxiu Wang, Ya Liu, Min Jia, Aizhen Zong, Fangling Du, Tongcheng Xu
Dietary diacylglycerol ameliorates obesity-induced osteoporosis by attenuating NF-κB signaling to rebalance osteoblast and osteoclast activity.
The content of this RSS Feed (c) The Royal Society of Chemistry

The potential of natural dietary products in mitigating inflammation during pregnancy

Food Funct., 2026, 17,3050-3076
DOI: 10.1039/D5FO05195A, Review Article

Janice García-Quiroz, Abigail García-Morales, Euclides Avila, Consuelo Lomas-Soria, Andrea Olmos-Ortiz, Lorenza Díaz
Inflammatory factors during pregnancy can harm both the mother and the fetus by activating host cell pattern recognition receptors (PRRs). A balanced anti-inflammatory diet may help prevent and mitigate these complications.
The content of this RSS Feed (c) The Royal Society of Chemistry

Advances in the preparation, characterization and biological activities of food-borne selenium-enriched peptides

Food Funct., 2026, 17,3008-3027
DOI: 10.1039/D5FO04850H, Review Article

Ying-Chao Qiu, Zi-Ying Zhao, Meng-Jiao Wang, Ying-Hua Zhang
This review systematically summarizes the preparation strategies, structural characterization techniques, and biological activities of selenium-enriched peptides.
The content of this RSS Feed (c) The Royal Society of Chemistry

Comparative evaluation of the short-chain fatty acids formate, propionate, and valerate on intestinal barrier maturation and bone development in neonatal mice

Food Funct., 2026, 17,3372-3385
DOI: 10.1039/D5FO05394C, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Xue Yang, Xinke Li, Xuan Zhang, Lu Meng, Jiaqi Wang, Nan Zheng
Comparative evaluation of short-chain fatty acids shows that valerate most strongly promotes neonatal growth, intestinal barrier maturation, immune regulation, and bone development, with distict shifts in gut microbiota.
The content of this RSS Feed (c) The Royal Society of Chemistry

Bilberry (Vaccinium myrtillus L.) extract alleviates gestational diabetes mellitus by coordinating TGR5/FXR signaling via a gut microbiota–bile acid axis

Food Funct., 2026, 17,3336-3352
DOI: 10.1039/D5FO04882F, Paper

Shunli Jiang, Qingyue Meng, Chenyun Jiang, Yunzhe Lv, Lingfei Liu, Ruining Xie, Fuli Ya, Qin Gao
Vaccinium myrtillus L. extract (VME) alleviates insulin resistance in HFD-induced GDM via regulating the gut microbiota-bile acid pathway.
The content of this RSS Feed (c) The Royal Society of Chemistry

Kaempferol alleviates right ventricular hypertrophy in high-altitude pulmonary hypertension rats by modulating the AMPK/ACC/CPT1B axis and the AMPK-mediated LDHA/PDHA1 pathway

Food Funct., 2026, 17,3172-3185
DOI: 10.1039/D5FO04265H, Paper

Qiongqiong Zhao, Shanshan Su, Ju Chen, Meiduo Huayu, Xingmei Nan, Xiaoping Li, Zhanqiang Li, Dianxiang Lu
Kaempferol protected the structure and function of right ventricle and attenuated RV remodeling in HAPH rats, potentially through the modulation of the AMPK/ACC/CPT1B axis and AMPK-mediated LDHA/PDHA1 pathway.
The content of this RSS Feed (c) The Royal Society of Chemistry

NAFLD-related SNPs are linked to changes in liver fat, as measured by the CAP score, and serum lipids in response to a 3-week sugar-sweetened beverage intervention: a pilot study

Food Funct., 2026, 17,3115-3127
DOI: 10.1039/D5FO03248B, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Faustina Therase Jeyaraj, Sai Sravani Vennam, Kendra Nelson, Katherine Watts, Lydia R. Goss, Brea C. Nance, Baba B. Mass, Venkata Saroja Voruganti
Role of genetic variation in changes in liver fat content and serum lipids in response to a 3-week sugar-sweetened beverage intervention.
The content of this RSS Feed (c) The Royal Society of Chemistry

Citrus unshiu fermented vinegar and Hovenia dulcis fruit extract formulation enhances alcohol metabolism and attenuates alcohol-induced hepatic injury

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO04017E, Paper

Wool Lim Park, Hye Ji Min, Hyun Dong Cho, Ji An Heo, Hwi Gon Kim, Kwon-Il Seo
A formulation of Citrus unshiu fermented vinegar and Hovenia dulcis fruit extract lowered blood ethanol and acetaldehyde in acute alcohol-treated rats and humans, and attenuated oxidative stress and liver injury in chronic alcohol-fed rats.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Therapeutic effects of selenium-enriched rapeseed against triple-negative breast cancer: involvement of Resolvin D5 activation and IL-17 signaling inhibition

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO05648A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Yuxin Lin, Tangyi Wang, Zhijing Wu, Li Wang, Zhiyao Yu, Jiangyun Wang, Tao Liu, Xiaoling Cai, Haoran Li, Yanming Ren, Zhanhai Su, Shoude Zhang, Juan An, Qiong Wu, Haiyan Wang
Dietary selenium-enriched rapeseed mobilizes Resolvin D5 to inhibit the IL-17 pathway and reinvigorate anti-tumor immunity.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Beyond nutrition: a comprehensive review of the multifaceted benefits of HMOs and Bifidobacterium-based synbiotics during early life

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00335D, Review Article

Xiangxin Wang, Qinggang Xie, Jufang Li, Shilong Jiang
Early in life, gut, immunity, growth, and brain development occur rapidly and vary considerably.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Genetic risk modifies the effect of exogenous nucleotides on insulin resistance in older adults: insights from multi-omics analyses

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO05425G, Paper

Ruisheng Fu, Shuyue Wang, Yuxiao Wu, Xueying Qin, Tao Huang, Yong Li, Meihong Xu
Nucleotides—fundamental cellular building blocks—are an underappreciated dietary component, especially in aging when metabolic resilience wanes.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lactobacillus plantarum RG-034 colonic soluble capsules alleviate functional constipation in rats by promoting short-chain fatty acid generation

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO02451J, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Fenglian Xu, Yi Zhang, Yulong Li, Ziyu Wang, Zijun Liu, Yu Zhao, Yuming Liu, Tengteng Huang, Li Gong, Weirong Fang
Lactobacillus plantarum RG-034 alleviates functional constipation and restores intestinal motility by improving gut microbiota, promoting SCFA production, and activating PI3K/AKT to promote ICC calcium influx and proliferation.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Limosilactobacillus fermentum 50 alleviates vulvovaginal Candidiasis via the gut–vagina axis: modulating microbiota, barrier function and inflammation

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00049E, Paper

Xiaoyue Bai, Zhichao Chen, Yizhi Jing, Jiahui Liu, Zheng Han, Qingqiu Ye, Yanling Hao, Zhengyuan Zhai
Vulvovaginal candidiasis (VVC) is a common vaginal disease characterized by inflammatory cell infiltration and vaginal microbiota dysbiosis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Acute response to a high-saturated-fat, high-refined-carbohydrate meal in healthy young men shows novel perturbation of multiple metabolic and defense pathways

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO04456A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Aimee L. Dordevic, Margaret Murray, Michael J. Houghton, Nina M. Trinquet, Nicole J. Kellow, Ralf B. Schittenhelm, Christopher K. Barlow, Kaitlin Day, Louise Bennett, Beau-Luke Colton, Gary Williamson
There is a decrease in plasma oxidative defense proteins after a high-saturated fat high-refined carbohydrate meal.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Resting-state brain connectivity following extra virgin olive oil intake in healthy adults: a randomised crossover pilot neuroimaging substudy

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO05016B, Communication

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Rocío M. Gutiérrez-Romero, Carolina Donat-Vargas, Emma Muñoz-Moreno, Alejandro Hinojosa-Moscoso, Polina Galkina, Camila Arancibia-Riveros, Inés Domínguez-López, Sara Hurtado-Barroso, Maria Pérez, Anna Vallverdú-Queralt, Rosa Casas, Ramón Estruch, Rosa M. Lamuela-Raventós
In this pilot substudy, EVOO intake was associated with higher urinary HT-glucuronide and occipital resting-state connectivity, with an intervention-dependent metabolite-connectivity interaction.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Assessing the diversity and functional profile of the “microbial proteome” in fermented foods

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO05039A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Laura Winkler, Ayesha Awan, Nicole M. Rideout, Manuel Kleiner
Fermented foods contain a large amount and diversity of microbial proteins which contribute to their nutritional profile.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Exploring the effects of Cheddar cheese intake on vitamin K status and lipid profiles in overweight middle-aged adults

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO05631D, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Sitong Zhou, Heleena Moni Bottu, Jean-Christophe Jacquier, Raquel Cama-Moncunill, Mark Timlin, Deirdre Hennessy, Michael O'Donovan, André Brodkorb, Jeremiah J. Sheehan, Eileen R. Gibney, Peter Dunne, Emma L. Feeney
Cheddar cheese intake may improve the vitamin K status, and vitamin K intake from cheese may induce sex-specific effects on blood lipid profiles in overweight middle-aged adults.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Fabrication of water-in-oil high internal phase emulsions containing astringent compounds for enhanced oral sensation

Food Funct., 2026, Accepted Manuscript
DOI: 10.1039/D6FO00380J, Paper

Haowen Sun, Xinying Wang, Jingjing Yu, Honggao Xu, Like Mao
This study aimed to mitigate astringency sensation from tannic acid (TA) or Rosa roxburghii Tratt juice (RRTJ) by incorporating them within the internal aqueous phase of water-in-oil high internal phase...
The content of this RSS Feed (c) The Royal Society of Chemistry

Potential antiobesity and antihepatic steatosis effects of a Capsosiphon fulvescens (maesaengi) ethanol extract: in vitro and in vivo studies

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO05258K, Paper

Sung Min Lee, Soo-yeon Park, Ji Yeon Kim
Capsosiphon fulvescens ethanol extract (CFE) suppresses lipid accumulation in adipocytes and hepatocytes and attenuates obesity and hepatic steatosis in HFD-fed mice by modulating lipid metabolism-related gene expression.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Structural activity remodeling of wheat protein peptides during simulated gastrointestinal digestion: insights into antioxidant and enzyme inhibitory functionalities

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO05244K, Paper

Siyu Hou, Penghui Zhao, Jianyu Huang, Zhizhi Yang, Yinchen Hou, Jicheng Chen
Bioactive food peptides demonstrate potential in chronic disease intervention, yet their structure–activity dynamics during digestion remain poorly understood.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Evaluation of the underutilized Malpighia glabra L. fruits as a future functional food: nutritional composition, phenolic profile, biological activities, and synergistic effects with pharmaceutical drugs

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO03782D, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Varongsiri Kemsawasd, Sirinapa Thangsiri, Yuraporn Sahasakul, Amornrat Aursalung, Woorawee Inthachat, Piya Temviriyanukul, Suwapat Kittibunchakul, Uthaiwan Suttisansanee
Malpighia glabra L., a non-commercial tropical fruit species in Thailand, was investigated regarding its nutritional composition, phenolic profile, and in vitro biological activities.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Diet–microbiota interactions influence pregnancy success in females undergoing artificial insemination: insights from the vaginal microbiota and Mediterranean diet

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO04208A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

M. Gimeno, M. Baizán-Urgell, M. Bernabeu, M. C. Collado, E. Garcia-Verdevio
Adherence to the Mediterranean diet is linked to vaginal microbiota profiles and fertility outcomes in women undergoing artificial insemination.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Red quinoa hydrolysate as a plant-based therapeutic alternative for damage induced by high cadmium concentrations to the vascular system in rats

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO04828A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Samia Hassan Husein Kanaan, Paola Zambelli Moraes, Katye Yasmin de Souza de Oliveira, Fernando Barbosa, José Eudes Gomes Pinheiro, Franck Maciel Peçanha, Dalton Valentim Vassallo, Marta Miguel-Castro, Giulia Alessandra Wiggers
Red quinoa hydrolysate as a plant-based therapeutic alternative for damage induced by high cadmium concentrations to the vascular system in rats.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Ketogenic diet-derived faecal microbiota transplantation improved sensorimotor gating deficits in an acute NMDA-receptor antagonist model of schizophrenia in mice

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00213G, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Ann-Katrin Kraeuter, Zoltan Sarnyai
Ketogenic diet-derived faecal microbial transplantation improved sensorimotor gating deficits in an acute NMDA receptor antagonist model of schizophrenia.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Associations between degree of food processing, inflammatory biomarkers and colorectal cancer survival: a prospective cohort study

Food Funct., 2026, Accepted Manuscript
DOI: 10.1039/D6FO00196C, Paper

Ya-Wen Tan, Qing-Jian Ou, Huan Xu, Yuan-Yuan Chen, Fang-Ting Lin, Yu-Jing Fang, Cai-Xia Zhang
The association between NOVA-classified food processing level and colorectal cancer (CRC) prognosis remains unclear, particularly regarding the potential mediating role of inflammation. We included 2,799 patients from Guangdong Colorectal Cancer...
The content of this RSS Feed (c) The Royal Society of Chemistry

Curcumin attenuates nanoparticle-induced renal injury via the PI3K/AKT signaling pathway

Food Funct., 2026, Accepted Manuscript
DOI: 10.1039/D6FO00638H, Paper

Huiyuan Rui, Xinran xu, Shuhui Liu, Xueli Gao, Xiaowen Jiang, Wenhui Yu
Exposure to polystyrene nanoplastics (PS-NPs) endangers human health, so exploring curcumin (Cur)'s nephroprotective effects against PS-NPs-induced injury is crucial. This research integrated network pharmacology with in vitro and in vivo...
The content of this RSS Feed (c) The Royal Society of Chemistry

SELFormer-guided discovery of xanthohumol and cirsilineol as multi-target natural therapeutics for type 2 diabetes: computational prediction and experimental validation

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO03765D, Paper

Junyu Zhou, Chen Li, Meiling Liu, Sunmin Park
Type 2 diabetes mellitus (T2DM) requires multi-target therapeutic approaches addressing both insulin resistance and insulin secretion deficits.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Integrated transcriptomic and proteomic analyses elucidate the stress tolerance network of Saccharomyces boulardii under gastrointestinal challenge

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO04958J, Paper

Dingkang Wang, Lerong Liu, Xiaoru Chen, Yiting Kang, Dan Li, Bin Ma, Yuexi Zhu, Yanqin Rong, Hongfei Yu, Yongjie Zhang
The probiotic yeast Saccharomyces boulardii is renowned for its clinical efficacy, which is intrinsically linked to its exceptional ability to survive the harsh gastrointestinal (GI) environment.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Combined effects of a low-dose multi-target supplement (CaHMB, CBP, and HA) on delaying musculoskeletal aging

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00352D, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Haoqi Chen, Junhong Peng, Shanshan Guo, Ting Chen, Si Chen, Xinyuan Jin, Wenge Huang, Chao Xu, Mengchu Li, Mengxing Xie, Mengtao Yang, Jinzhu Pang, Huilian Zhu
A low-dose combination of CaHMB, CBP, and HA delays age-related muscle and bone loss during the transition to old age, with comprehensive benefits potentially mediated by the muscle–bone axis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Bioconversion properties of the urate-lowering probiotic fermented Aronia melanocarpa (black chokeberry) and its antihyperuricemic capacity via regulating metabolic/immune pathways and gut microbiota

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00440G, Paper

Hongyu Zhang, Chaoran Li, Tianjiao Li, Fuyu Li, Xiangheng Cao, Yang Yang, Da Wang, Mingyou Yuan, Qiuyi Li, Xuebo Liu, Mengge Zhao
First, omics confirms metabolite changes after fermentation. In HUA mice, FAR and FARS modulate serum cytokines, suppress TLR4/MyD88/NF-κB pathway, and regulate urate-metabolizing factors. Plus, they elevate butyrate via guiding gut bacteria.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Crossing and metabolism of tyrosol and hydroxytyrosol by implementing an in vitro blood–brain barrier model of human primary cells

Food Funct., 2026, Advance Article
DOI: 10.1039/D6FO00323K, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Sonia Gulabrai-Díaz, Blanca Escudero-López, Carmen del Río, Joan Montaner, Marta Berzaghi, Pedro Mena, Ana M Troncoso, Ruth Hornedo-Ortega
Evaluation of the permeability of tyrosol and hydroxytyrosol by implementing a human-origin triple co-culture BBB model.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Simulated gastrointestinal digestion of cocoa powder (INFOGEST): methylxanthine bioaccessibility and antioxidant properties

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO05193B, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Leopoldo Rivera-Manzorro, María José Aliaño-González, Gerardo Fernández Barbero, Nuria Chinchilla, Francisco Antonio Macías, Miguel Palma-Lovillo, Ceferino Carrera
Cocoa (Theobroma cacao L.) is a rich source of bioactive compounds, including methylxanthines (theobromine and caffeine) and polyphenols, which are known for their stimulant, antioxidant, and cardioprotective properties.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Blueberry anthocyanin supplementation shows favorable trends in glycemic control and alters the gut microbiota in type 2 diabetes patients: a pilot study

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO05613F, Paper

Xindi Hu, Lujing Xu, Ying Li, Xingyu Zhao, Yakun Xing, Jin Feng, Jiawei Zheng, Cheng Xue, Wuyang Huang, Shan Lu
Blueberry anthocyanins may modulate the gut microbiota and improve glucose metabolism in T2DM.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Effect of compound fish oil capsules on microvascular function in hypertensive individuals: a triple-blind, randomized, placebo-controlled pilot trial

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO05343A, Paper

Bingzheng Liu, Wenlong Wang, Aiping Teng, Chengcheng Yu, Yaqian Liang, Anchao Liu, Xiao Wu, Duo Li, Hui Ma, Kelei Li
In the left anterior descending artery (LAD), the end-diastolic velocity (EDV) and peak diastolic velocity (PDV) significantly increased in the FO group.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

A composite protein enriched with threonine, lysine, and tryptophan improves osteoporosis by modulating the composition and metabolism of the gut microbiota

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO04652A, Paper

Chonghua Fan, Zhenye Shi, Bailiang Li, Song Wang, Zhongjiang Wang
Osteoporosis is a metabolic bone disorder characterized by impaired bone metabolism and increased fracture risk. The optimized protein blend demonstrates efficacy in improving osteoporosis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Associations among dietary nitrosamine intake, fecal N-nitroso compounds and intestinal microbiota in adults according to intestinal mucosa damage

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO02980E, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Sergio Ruiz-Saavedra, Tuulia Kreetta Pietilä, Aida Zapico, Nuria Salazar, Silvia Arboleya, Anne-Maria Pajari, Sonia González, Clara G. de los Reyes-Gavilán
Dietary intake of nitrosamines and gut formation of N-nitroso compounds (NOCs) has been proposed as one of the mechanisms explaining the association between consumption of red and processed meat and the increased risk of colorectal cancer (CRC).
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Folic acid alleviates endothelial dysfunction caused by T2DM-induced ferroptosis by activating the SIRT6/NRF2/GPX4 signaling pathway

Food Funct., 2026, Advance Article
DOI: 10.1039/D5FO04381F, Paper

Lei Hong, Xinqi Lou, Yingjie Zha, Xuejie Fu, Tuanjie Che, Shigang Qiao, Chen Wang, Jianzhong An
Folic acid protects endothelial cell function against T2DM-induced ferroptosis by activating the SIRT6/NRF2/GPX4 signaling pathway.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry