RSC - Analyst latest articles

An intelligent DNAzyme theranostic probe for in situ FTO bioimaging and real-time therapeutic efficacy evaluation in living cells

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00400H, Paper

Haorong Liu, Shengrong Yu, Rong Feng, Jingwen Chen, Gege Xie, Xiangwu Wu, Tao Zhang, Jian He, Yongxiang Wu, Keqi Tang
Real‑time bioimaging of epigenetic dynamics in living cells is essential for precision oncology. However, it remains technically challenging due to the lack of theranostic probes capable of both sensitive detection...
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Frontiers in Raman Nano-diagnostics: SERS and TERS of Extracellular vesicles for Cancer Detection

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00476H, Minireview

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Lorena Veliz, Francois Lagugné-Labarthet
Efforts to create rapid, non-invasive, and reliable cancer diagnostics have increasingly focused on extracellular vesicles (EVs), nanoscale carriers of proteins, lipids, and nucleic acids that mirror the molecular state of...
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Rapid antimicrobial susceptibility testing directly from positive blood cultures

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00259E, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Mohammad Osaid, Daniel Nathan Tomás Cançado, Daniel Spencer, Wouter van der Wijngaart, Hywel Morgan
A smart centrifugation and selective lysis workflow enables rapid antimicrobial susceptibility testing directly from positive blood cultures within 3 h using impedance flow cytometry.
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Dual-readout villus-like scaffold microfluidic platform for quantitative analysis of gut microbiota formation under perfusion

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00592F, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Yota Yamakawa, Ryoo Hidaka, Wataru Iwasaki, Sachiko Ide, Noritada Kaji
The integrated device system consists of a villus-like scaffold architecture and a perfusion operation for dual-readout quantification in gut microbiota studies.
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Urchin-like covalent organic framework microspheres for electrochemical organophosphorus pesticide sensing

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00539J, Communication

Hongze Yao, Tong Lu, Yu Wu, Fang Duan, Shuanglong Lu, Baochun Guo, Mingliang Du
The electrochemical detection of organophosphates (OPs) using acetylcholinesterase (AChE) immobilized on a glassy carbon electrode (GCE).
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Barcoding for isobaric tagging of carboxylic acids and amines metabolites

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00437G, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Briana M. Tengan, Michael R. Armbruster, Julius Agongo, Christopher K. Arnatt, James L. Edwards
Amine and carboxylate metabolites are tagged with unique set of bar-coded isobaric tags which render moiety identifying reporter ions and quantitation. Metabolite changes from genetic knockout are reported.
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An integrated rotational paper-based ELISA platform for multiplex inflammatory biomarker analysis in whole blood with a DIY centrifuge

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00384B, Paper

Jingying Guo, Ji Qi, Lianglong Yu, Jiemei Li, Luchang Song, Bowei Li, Xiaoyan Wang, Lingxin Chen
A low-cost portable DIY centrifuge, combined with a rotational paper-based chip, employs a sandwich enzyme-linked immunosorbent colorimetric assay to detect CRP and PCT.
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Intelligent quantification of Mn(VII) using a YOLO v3 artificial intelligence-driven smartphone monitoring platform based on nitrogen-doped blue fluorescence carbon dots

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00481D, Paper

Xiaofeng Li, Liru Yan, Jiaqi He, Pengfei Guo, Xin Qiao, Liqin Cui, Shaomin Shuang, Lihong Shi
YOLO v3 artificial intelligence-driven smartphone monitoring platform for intelligent quantification of Mn(VII).
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Enzyme-assisted catalytic hairpin assembly based aggregation-induced emission assay for trace miRNA-196a in serum

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00345A, Paper

Zihan Xu, Yongda Lu, Jieyu Yan, Yan Wang, Zhengjiang Wu, Yifei Li, Jiayin Zhang, Kun Han
An eaCHA–AIE biosensor detects miRNA–196a with an LOD of 120 fM and is applicable to clinical serum for early pancreatic cancer diagnosis.
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Nanostructures for Photoelectrochemical Biosensing

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00334F, Critical Review

Hongbo Li, Qiuju Qiao, Xinrong Gu, Jing Li
Photoelectrochemical (PEC) biosensing has emerged as a highly promising analytical technique, leveraging the synergistic interplay of light and electrochemical processes to achieve sensitive, selective, and rapid detection of various molecules....
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An iron-doped Cu2O nanozyme enables highly sensitive colorimetric detection of vitamin E in serum

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00444J, Paper

Xiangyu Feng, Haibing Zhu, Chuanli Ren, Fu-an Wang, Zhanjun Yang, Guiling Li
An Fe-doped Cu₂O (Fe-Cu₂O) nanozyme with 7.2-fold enhanced peroxidase-like activity was developed to construct a colorimetric sensor for the sensitive detection of vitamin E, showing great potential for the detection of reducing biomolecules.
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Thermodesorption Kinetics of Nikethamide on Oxidized Tungsten Surfaces

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00514D, Paper

Makhmanazar M. Nazarov, Ilkhomjon M. Saydumarov, Azim Radjabov, Shovkatjon Akhunov, Sherzod M. Akhmedov, Saida Iskhakova, Dilshadbek Tursunbaevich Usmanov
The analeptic substance nikethamide was studied under both stationary and non-stationary processes using the surface ionization method. The composition of ions formed during the thermal ionization of nikethamide molecules from...
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IrTMes – a stable SABRE catalyst for the hyperpolarization of [1-13C]-pyruvate

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00328A, Communication

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Jakoba Wacker, Jan G. Korvink, Sören Lehmkuhl
A stable polarization transfer catalyst IrTMes for the SABRE hyperpolarization of [1-¹³C]-pyruvate at room temperature.
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DVB-cross-linked latex microspheres to uniformly host Eu(III) chelates with moderate swelling capacity for high performance quantitative LFIA strips

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00194G, Paper

Jiannan Jia, Hongjian Chen, Songle Wang, Yunpeng Wang, Qike Wang, Dong Chen, Shisheng Ling, Zhenzhen Ge, Wenkun Dong, Mi Yan, Zhiyu Wang, Xianping Fan, Xu Liang, Qiang Xu, Xvsheng Qiao
DVB-cross-link latex microspheres can uniformly host Eu(TTA)₃(TPPO)₂. It shows efficient PL, rich –COOH on surface and stable Zeta potential. The microspheres achieve a LOD of 0.08 ng/mL and a CV value < 7.34% in the LFIA strip test of CRP.
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A magnetic polymer adsorbent based on porous polystyrene microspheres for efficient extraction of conotoxins in biological fluids

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00324A, Paper

Xinlan Li, Songlin Liu, Yuan Luo, Shishi Liu, Xiujun Cao, Jun Lu, Chunhui Deng
Conotoxins, isolated from the venom produced by marine snails of the Conus genus, are a range of bioactive, disulfide-rich peptides. However, their narrow therapeutic window and significant interindividual variability make...
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Fatty diacid-modified FAP-targeted NIR fluorescent probes with modulated pharmacokinetics for enhanced tumor imaging

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00311G, Paper

Yilin Liao, Hongwei Hou, Yuanhong Xu, Jinghong Li
Fatty diacid modification enables albumin-associated pharmacokinetic tuning of FAP-targeted NIR probes, enhancing tumor retention and imaging contrast.
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Electroanalysis in a Dissolving Microdroplet

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00461J, Perspective

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Savannah Hatch, James Nguyen, Jocelyn April Dumouchel, Ashutosh Rana, Jeffrey E Dick
Electroanalytical chemistry has increasingly focused on probing dynamic, non-equilibrium processes that remain difficult to access using conventional approaches like bulk measurements where the electrolyte and evaporation/dissolution processes are approached as...
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An AuNPs modified photonic crystal microfluidic chip for acetamiprid and myclobutanil detection

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00154H, Paper

Yu Sun, Shuo Li, Peng Tang, Yuankai Zhang, Chao Yi, Wang Peng
A microfluidic chip integrating AuNPs-modified photonic crystal has been developed for rapid pesticide detection. This chip enables the detection limit of acetamiprid and myclobutanil to reach 10⁻⁴ g L⁻¹ within one minute.
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Impact of Preparation Methods and Storage Conditions for Optimization of the Fecal Metabolome Storage

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00237D, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Vladyslav Dovhalyuk, Daniel Globisch
Untargeted fecal metabolomics has gained a higher scientific interest in the past decade, due to the increased importance of the gut microbiome metabolism. It is highly sensitive to preanalytical variations....
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Construction and application of a microfluidic-droplet system for high-throughput screening of amylase-producing strains from jiuqu

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00443A, Paper

Honghua Li, Qiyu Wu, Xiaorui Feng, Xiaogang Liu, Ying Wang, Ling Lin
Amylases are crucial biocatalysts in brewing and bioindustries, yet isolating high-yielding producers from complex fermentation starters like Chinese Baijiu jiuqu remains slow and low-throughput.
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Raman spectroscopic detection of salivary thiocyanate for smoking exposure stratification

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00372A, Paper

Pushpak U. Shah, Punnya V. Angadi, Darshan Chikkanayakanahalli Mukunda, Jiro Karlo, Surya Pratap Singh
This study demonstrates the potential of non-invasive salivary Raman spectroscopy for rapid stratification of non-smokers, short-term smokers, and long-term smokers using thiocyanate-associated spectral variations.
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Methylation-enhanced fluorescent dyes for highly sensitive detection of hypochlorous acid and biological imaging

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00445H, Paper

Chong Chang, Jianxing Song, Jiayu Yang, Shijun Chen, Qiye Liu, Wei Shu, Chaoyuan Zeng, Weijie Chi
Methylation steric hindrance lowers HR factors and reorganization energy, boosting fluorescence and enabling selective in vivo HClO imaging.
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Regeneration-on-a-chip: a planarian microfluidic device enabling automated cultivation, individual tracking and in vivo imaging for regeneration study

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00281A, Paper

Runtao Zhong, Xiaoyu Wang, Hui Li, Qi Zhang
Freshwater planarian, a model organism renowned for its remarkable regenerative capabilities, is widely used in studies of regenerative mechanisms and stem cell biology. However, current research faces challenges in automated...
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Ultra-performance convergence chromatography tandem mass spectrometry strategy for quantification of monodisperse polyethylene glycol polymers coupled with multiple fragmentation to enhance sensitivity

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00305B, Paper

Jiarui Zhang, Hui Miao, Jiale Liu, Xinyue Zhou, Yue Deng, Shuang Feng, Yalin Xi, Meiyun Shi, Lei Yin
Accurate quantification of hydrophilic monodisperse polyethylene glycol (PEG) derivatives in complex biological matrices remains challenging due to substantial matrix interference and poor retention using conventional chromatographic systems.This study presents an...
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Synthesis of Rhodamine B Hydrazine Derivatives and Their Application in Glycan Analysis

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00299D, Paper

Yu-Nan Chen, Xiao-Long Hou, Ying Liu, Xuyang Shen, Yi-xuan Gu, Yue Yu, Xin Zheng, Ying-Lin Zhou, Xinxiang Zhang
Due to the high molecular weight and polarity, glycans suffer low ionization efficiency in electrospray ionization mass spectrometry (ESI-MS). It is necessary to chemically derivatize them for MS response improvement....
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A Review on Organic Molecule-Based Fluorescent and Colorimetric Chemosensors for Bi3+: Recent Advances, Challenges, and Future Directions

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00358C, Minireview

Saikat Kumar Manna, Sanchita Mondal, Arnab Rout, Subrata Mukhopadhyay
In recent years, the advancement of fluorometric and colorimetric chemosensors for Bi3+ ion receives notable attention from researchers owing to the pharmacological, environmental, and industrial relevance of Bi³⁺ ions. In...
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Colloidal gold immunochromatographic assay for mycophenolic acid in human plasma

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00484A, Paper

Jiayi Liu, Lingling Guo, Liqiang Liu, Xinxin Xu, Hua Kuang, Chuanlai Xu
Mycophenolic acid (MPA), an immunosuppressive metabolite of Penicillium fungi with a narrow therapeutic window, poses significant clinicals risks of toxicity or transplant rejection if its concentration is not strictly controlled....
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Molecular imprinting-based pseudo-ELISA: Recent advances

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00275G, Critical Review

Yuqin Ge, Hongkang Wang, Tianhai Ji
Enzyme-linked immunosorbent assay (ELISA) is a versatile analytical method widely used in medical, biological, chemical and many other fields. Antibodies play an important role in recognizing target analytes within complex...
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In situ electrodeposition of Ni(OH)2 nanoparticles for highly sensitive electrochemical detection of ascorbic acid

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00378H, Paper

Ruijuan Wang, Zhenlan Qin, Xiuju Huang, Congxue Su, Yougang Luo, Yiqi Jing, Rong Wang
Ni(OH)₂ nanoparticles are in situ electrodeposited on carbon paper, and the obtained electrode exhibits high sensitivity, good repeatability and excellent actual detection.
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Photo-switchable supramolecular glycochips for capturing suspension tumor cells and real-time profiling of cell surface glycosylation

Analyst, 2026, 151,3077-3080
DOI: 10.1039/D6AN00395H, Communication

Biqing Chen, Xian Chen, Lan Chen, Huanyu Liu, Juan Liu, Yuxin Pei, Teodor Aastrup, Yanbin He, Changping Hu, Zhichao Pei, Yuchao Lu
A photo-switchable supramolecular glycochip was fabricated via host–guest complexation between surface-immobilized azobenzene and galactose-modified pillar[5]arene.
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Advances of hydrogel-modified silica as the stationary phase in high-performance liquid chromatography

Analyst, 2026, 151,3017-3027
DOI: 10.1039/D6AN00404K, Perspective

Tong Zhang, Xiaojing Liang, Hongfang Lin, Rui Liu, Na Li, Zhixia Li, Lei Liu, Yuting Zhang
Hydrogel-functionalized silica is used as the stationary phase in liquid chromatography.
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Cellular level lipidomics of two-dimensional cultures of adherent gut epithelial cell lines confirms a metabolic switch

Analyst, 2026, 151,3267-3275
DOI: 10.1039/D5AN01183C, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Qianying Xu, Jake A. Penny, Emily Fraser, Federica Orsenigo, Matteo Barberis, Lee A. Gethings, Melanie J. Bailey, E. N. Clare Mills
Advances in lipidomics analysis at a cellular level highlight important metabolic differences between Caco-2 and HT29-MTX cell lines which are widely used to study gut uptake and metabolism of nutrients and pharmaceuticals.
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Toward real-time protein profiling in biofluids using discriminative Raman spectral markers

Analyst, 2026, 151,3141-3152
DOI: 10.1039/D5AN00887E, Paper

Kadambari Jandhyala, Priyanka Dey
Simultaneous analysis of multiple proteins in liquid biopsies is essential for accurate disease diagnosis and monitoring yet remains challenging in complex biological matrices when proteins exhibit high structural similarity.
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Portable multichannel immunoassay of coxsackievirus A6 using a coordination-engineered iridium-doped ZIF-8 nanozyme

Analyst, 2026, 151,3091-3099
DOI: 10.1039/D6AN00297H, Paper

Fangming Zhu, Rongxiu Deng, Xue Liu, Guoliang Dai, Yuyang Zhou
An iridium-doped ZIF-based nanozyme with peroxidase-like activity was developed via a one-pot method to enhance the binding ability between H₂O₂ and doped iridium atoms.
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GravSorter: a forward-genetics tool for studying gravity response in Caenorhabditis elegans

Analyst, 2026, 151,3118-3129
DOI: 10.1039/D5AN01231G, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Hui Ma, David M. Raizen, Haim H. Bau
GravSorter: Diverse genotypes are placed in a vertical liquid column slightly denser than the worms. Gravitaxis-competent worms swim downward, while deficient worms float and are collected for downstream sorting and sequencing.
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HDX-MS epitope characterization for evaluating antibody suitability for ELISA-based in vitro potency testing of vaccines

Analyst, 2026, 151,3227-3238
DOI: 10.1039/D6AN00215C, Paper

Alex Listigovers, Liwei He, Lidice Bernardo Reyes, Camille Houy, Luciano Ettorre, Nelson Eng, Jason Szeto, Romain Pizzato, Derek J. Wilson, D. Andrew James, Shaolong Zhu
ELISA requirements: a crosslinked toxoid presents immune epitopes. Antibodies are screened by hydrogen deuterium exchange. Antibodies targeting separated neutralizing epitopes support in vitro potency testing, replacing in vivo.
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Monte Carlo-like peaks assignment using a time-resolved in situ NMR approach for complex reaction monitoring: a case study of the photodegradation of retinyl acetate

Analyst, 2026, 151,3249-3259
DOI: 10.1039/D6AN00072J, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Farwa Khalid, Chunchesh Malangi Gajendramurthy, Franz F. Westermair, Lena Miler, Ruth M. Gschwind, Tomasz Ratajczyk, Mateusz Urbańczyk
We demonstrate a method for complex reaction monitoring that combines two approaches: time-resolved non-uniform sampling and time-resolved diffusion NMR. The new approach was demonstrated in the study of the photodegradation of retinyl acetate.
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Smartphone assisted high-performance fluorescence/colorimetric dual-mode enantioselective identification of glutamic acid in complex samples

Analyst, 2026, 151,3165-3173
DOI: 10.1039/D6AN00240D, Paper

Cancan Lu, Chen Liu, Yaning Duan, Tao Yi, Cuiling Ren, Hongli Chen
The synthesized fluorescent/colorimetric dual-mode probe can sensitively detect Glu enantiomers in biological samples. The probe can specifically detect D/L-Glu in a mixture of 19 kinds of amino acids and 16 kinds of ions.
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A nanopore-based enzyme-assisted biomarker detection method for chronic obstructive pulmonary disease

Analyst, 2026, 151,3298-3304
DOI: 10.1039/D6AN00373G, Paper

Qianyuan Ren, Yakun Yi, Shihong Li
We present a nanopore-based dual-biomarker assay for ultrasensitive miR-150-5p and VEGF165 detection, providing a promising method for early screening of Chronic obstructive pulmonary disease (COPD) and its associated pulmonary hypertension.
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Metabolomics in the wild: research opportunities, challenges, and regulatory potential for effects-based environmental monitoring

Analyst, 2026, 151,3056-3076
DOI: 10.1039/D6AN00140H, Critical Review

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Georgia M. Sinclair, Sarah L. Green, Ryan Lester, Katherine J. Jeppe, Steven D. Melvin, Sara M. Long, Oliver A. H. Jones, David J. Beale
Field-based metabolomics detects early biological responses to complex contaminant mixtures in real ecosystems. Integrated with chemistry and ecology, it supports effects-based monitoring and regulatory decision-making.
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Visualizing nanoplastic–metal ion co-exposure stress with an NIR biothiol responsive fluorescent probe

Analyst, 2026, 151,3291-3297
DOI: 10.1039/D6AN00278A, Paper

Shaoyu Wei, Liangwei Zhang, Jiangkun Tan, Shudi Liu, Maryam Arabi, Abbas Ostovan, Xuming Zhuang, Lingxin Chen
A near infrared biothiol fluorescent probe has been developed for studying nanoplastic–metal ion complex co-exposure induced oxidative stress, revealing that charge and lysosomal function may be involved in the process.
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DNA nanotechnology for nucleic acid analysis: detection of RNA and dsDNA amplicons using a multifunctional DNAzyme nanomachine (DNM)

Analyst, 2026, 151,3260-3266
DOI: 10.1039/D6AN00265J, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Muhannad Ateiah, Sofia S. Zablotskaya, Maria S. Rubel, Dmitry M. Kolpashchikov
A multivalent 10–23 DNAzyme-based molecular nanomachine (DNM) enables sensitive, selective, and amplification-free detection of structured ssRNA and dsDNA.
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Effect of O-acetylation on ketene and carbonyl yields from conventional and emerging cannabinoids

Analyst, 2026, 151,3239-3248
DOI: 10.1039/D6AN00190D, Paper

Rhianna L. Evans, C. Noel Corley, Haylee C. Hunsaker, Sascha C. T. Nicklisch, Allison K. Ehrlich, Tran B. Nguyen
The vaping of popular and emerging cannabinoid O-acetates leads to the formation of ketene and carbonyls in high yields (1–5%), exceeding NIOSH safety limits of inhalation toxicity and indicating further regulation of these products is required.
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Interpretable machine learning model-driven electrochemical impedance spectroscopic analysis for the determination of nitrate, nitrite, and ammonium ions in water

Analyst, 2026, 151,3276-3290
DOI: 10.1039/D5AN01279A, Paper

K. Reji, Ramakrishnan Vishnuraj, Adithyakrishna Narayanaswamy, Vishnuvarthan Rajagopal, S. Vishnu, Murali Rangarajan
A machine-learning framework combining hybrid tree, principal component analysis, and stacked ensemble models is used to predict concentrations of nitrate, nitrite and ammonium ions in water from electrochemical impedance spectroscopy measurements.
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A portable fiber-optic sensor based on the UiO66–lucigenin complex for chloride ion concentration measurement

Analyst, 2026, 151,3214-3226
DOI: 10.1039/D6AN00101G, Paper

Runqi Yao, Jixing Huang, Zelin Gao, Hengbiao Zhang, Li Yang, Dekui Zhang, Tuanjie Che, YuChao Li, Honghan Dong, Xusheng Xia, Ning Wang, Liyun Ding
Detecting the concentration of chloride ions in water and soil is of great significance for understanding chloride behavior in the ocean and monitoring environmental pollutants.
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Ultra-trace electrochemical determination of total arsenic in actual water samples and food matrices using a nano-granular gold–copper modified glassy carbon electrode (NG-AuCu/GCE)

Analyst, 2026, 151,3197-3213
DOI: 10.1039/D6AN00044D, Paper

Sadia Yousaf, Usman Naseer, Mehwish Shah, Liufang Chen, Hailong Yan, Qingyun Cai
A glassy carbon electrode is modified with a nano-granular network of gold–copper (NG-AuCu/GCE) for total arsenic determination in actual water and food matrices.
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Lanthanide complex-based dual-modal probes for background-free time-gated luminescence and 19F magnetic resonance detection of hypochlorous acid in acute kidney injury

Analyst, 2026, 151,3108-3117
DOI: 10.1039/D6AN00197A, Paper

Shuqi Duan, Qi Liu, Xinyue Zhang, Wenzhu Zhang, Jingli Yuan, Bo Song
A lanthanide complex probe, Ln(SDHH)₃(DPBT) (Ln³⁺ = Eu³⁺, Gd³⁺), as a dual-modal platform for TGL and ¹⁹F MR detection of HClO in acute kidney injury.
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Application of an Astragalus biochar molecularly imprinted electrochemical sensor for highly sensitive sensing and detection of triazophos in tea

Analyst, 2026, 151,3184-3196
DOI: 10.1039/D6AN00251J, Paper

Dongdong Cheng, Jia Li, Xin Wang, Yi Li, Pen Jin, Jun Lin, Meng Li, Ruojia Li, Yongquan Dai, Weicheng Qin, Binlian Jiang, Zegen Wang, Lina Lu, Xiaojun Yang
In this study, a novel electrochemical sensing interface was developed for the detection of triazophos (TAP) in tea.
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Duplex-specific nuclease-assisted isothermal signal amplification coupled with HPLC-UV for simultaneous detection of multiple microRNAs

Analyst, 2026, 151,3100-3107
DOI: 10.1039/D6AN00272B, Paper

Haoran Qiu, Jialin Li, Yu Han, Hao Wu, Xin Sun
A DSN coupled HPLC-UV method enables multiplexed miRNA detection in a single reaction with performance comparable to that of stem–loop RT-qPCR.
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Development of a surface enhanced Raman scattering lateral flow immunoassay with prolonged reproducibility and stability over time

Analyst, 2026, 151,3130-3140
DOI: 10.1039/D6AN00053C, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Sian Sloan-Dennison, Ben Clark, Kathleen M. Scullion, Fiona Smillie, Stacey Laing, Paul Fineran, Joanne Mair, Cicely Rathmell, Dieter Bingemann, Jonathan Faircloth, David Creasey, Neil C. Shand, Chris J. Weir, James W. Dear, Duncan Graham, Karen Faulds
Lateral flow immunoassays (LFIAs) coupled to surface enhanced Raman scattering (SERS) measurements can produce quantitative outputs with excellent reproducbility over a prolonged period of time.
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A simple photothermal paper-based analytical device using silver nanomaterials for quantitative mercury ion monitoring in drinking water and Wolffia samples

Analyst, 2026, 151,3174-3183
DOI: 10.1039/D6AN00094K, Paper

Tapparath Leelasattarathkul, Kawin Khachornsakkul, Pattarawadee Wichaiwong, Wijitar Dungchai
A highly sensitive and cost-effective photothermal-based paper analytical device (PT-PAD) has been developed using silver nanomaterials to monitor Hg²⁺ levels.
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Exploring the role of microfluidic paper-based analytical devices in salivary diagnostics: from concept to clinical applications

Analyst, 2026, 151,3028-3055
DOI: 10.1039/D5AN01316J, Critical Review

Lucas R. Sousa, Larissa G. Velasco, Sandra G. Vlachovsky, Federico Figueredo, Eduardo Cortón, Wendell K. T. Coltro
Microfluidic paper-based analytical devices (µPADs) have evolved significantly over the last few decades, from simple colorimetric strips to multifunctional lab-on-a-chip systems.
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A low-cost visible and near-infrared (Vis-NIR) portable multispectral imager for fast drug analysis

Analyst, 2026, 151,3153-3164
DOI: 10.1039/D6AN00059B, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Erwin Winkler Martinez, Ali Tfayli, Thomas Nappez, Jean-Philippe Michel, Douglas N. Rutledge, Pierre Chaminade, Sana Tfaili
The prevalence of substandard and falsified (SF) drugs requires the development of effective identification and differentiation methods to distinguish genuine from SF medications.
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Deep profiling of porcine brain gangliosides enabled by TiO2 magnetic nanoparticle-based enrichment and advanced lipidomic analysis

Analyst, 2026, 151,3081-3090
DOI: 10.1039/D6AN00100A, Paper

Yichun Wang, Yu Xia
The TiO₂ MNP-based enrichment coupled with HILIC-TIMS-MS/MS enables comprehensive profiling of porcine brain gangliosides, extending detection to 40 subclasses and over 300 species, including rare lipids such as GD1c.
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A CoFe2O4 nanozyme mediated chemiluminescence imaging–colorimetric dual-mode sensor for monitoring ascorbic acid

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00496B, Paper

Ye Zhang, Maoying Peng, Caiqiao Qin, Yuchen Du, Feng Shi, Juan Li, Zhanjun Yang, Wei Ma
A CoFe₂O₄ nanozyme-mediated chemiluminescence (CL) imaging-colorimetric dual-mode sensor was proposed for accurate detection of ascorbic acid.
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Advanced X-ray radiographic imaging analysis for identifying water dynamics regime of polymer electrolyte fuel cells

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00365F, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Wataru Yoshimune
Operando X-ray radiography is widely used to evaluate liquid water distributions in polymer electrolyte fuel cells, yet conventional analyses typically condense pixel-resolved time series into spatiotemporal averages, potentially obscuring dynamically...
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Current trends in machine learning for surface-enhanced Raman spectroscopy

Analyst, 2026, Advance Article
DOI: 10.1039/D5AN01346A, Critical Review

Ruihao Luo, Sujia Jiao, Jyothi B. Nair, Arna Ghosh, Klaudziya Kamiak, Jürgen Popp, Dana Cialla-May, Thomas Bocklitz
Surface-enhanced Raman spectroscopy (SERS) is being transformed by the widespread adoption of artificial intelligence across the full methodological spectrum.
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Revealing potassium ion storage in individual Prussian blue nanoparticles with distinct crystallinity via scanning electrochemical cell microscopy

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00435K, Paper

Mengyao Cao, Yaqi Xiong, Cong Gao, Xinyu Guo, Jia Yin, Mahmoud Elsayed Hafez, Qianjin Chen
Potassium ion storage in individual Prussian Blue nanoparticles with distinct crystallinity was investigated.
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Low-cost bimetallic FeNi alloy nanoparticles loaded on nitrogen-doped carbon nanotubes for electrochemical sensing of copper ions

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00095A, Paper

Yao Yao, Jun-Chang Xue, Yue Jiang, Heng-Ye Li, Zhong-Xia Wang, Rui Zhang, Fen-Ying Kong, Wei Wang
Inexpensive, highly active, and stable FeNi/N-CNT nanocomposites were used as electrode modifiers for the highly sensitive detection of Cu²⁺.
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Dual-parameter self-calibrating probes for organelle polarity by decoupling viscosity from polarity

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00249H, Communication

Lei Huang, Chuanhao Liu, Wenxiao Deng, Yuchang Tan, Yanfei Tan, Yan Huang
To overcome the limitations of intensity- or wavelength-based polarity sensing in cells, we developed a novel fluorophore utilizing steric hindrance to resist viscosity interference while maintaining high polarity sensitivity and PLQY.
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A sensitive electrochemical sensor with Hf-MOF@activated Ketjen black/calix[4]arene composite for the detection of 2,2′-methylenebis(4-chlorophenol) in environmental water

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00351F, Paper

Yu Xie, Jingwen Meng, Zhijie Zhu, Genhe He, Ronghua Hu, Xiuguang Yi, Kalle Salminen
A novel Hf-MOF@activated Ketjen black/calix[4]arenes composite modified electrode sensor was fabricated for the sensitive detection of dichlorophenol in environmental water samples.
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Structure-aware fragment assignment for interpreting tandem mass spectrometry of modified and cyclic peptides

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00162A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

V. Erckes, A. Misiek, A. Streuli, C. Steuer
Cyclized or chemically modified peptidomimetics challenge MS/MS interpretation because fragmentation extends beyond canonical backbone cleavages or needs multiple bond breaks to yield sequence-informative ions.
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Fluorous nanoemulsion optodes with Förster resonance energy transfer-based fluorescence amplification toward highly-sensitive and selective detection of perfluorooctanesulfonate

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00189K, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Soraka Iwamoto, Tatsuro Endo, Hideaki Hisamoto
FRET-based fluorous nanoemulsion optodes enable highly sensitive and selective PFOS⁻ detection down to the 10⁻⁸ M level with a rapid response.
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An integrated optofluidic platform enabling label-free single-cell sorting and culture

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00203J, Paper

Baojian Zhang, Fuyuan Chen, Liru Zhao, Mengting Ming, Meina Chen, Chunfang Deng, Yuntong Wang, Huabing Yin, Bei Li, Peng Liang
We present OTMA, an optofluidic platform achieving deterministic, label-free single-cell sorting with >90% viability by decoupling optical trapping from hydrodynamic drag, enabling high-fidelity rare-cell research.
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An IFE-based lysosome-targeted probe for the differential detection and bioimaging of biothiols

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00211K, Paper

Yuan Xu, Yujia Hou, Tongtong Zhao, Huilin Chen, Hanxi Chai, Zhengrui Zhang, Zhuoyan Cao, Kaixin Xie, Qiaoling Liu
Biothiols (Cys, Hcy, and GSH) are generated by reducing disulfide bonds with the help of proteolysis in lysosomes, and these three biothiols play different roles in preserving the optimal activity of lysosomes.
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Ultramicroelectrode fabrication guidelines for multifunctional scanning electrochemical microscopy

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00234J, Paper

Congshan Guo, Zhizhen Lv, Jigui Tang, Jingshu Hui
Dual-disk electrodes with low RG values and narrow gaps were fabricated reproducibly by combining a thick-wall nanopipette template with tip forging.
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Ultrasensitive Triple-Mode Nile Red-L64 Niosome Nanothermometers for Real-Time Cellular Thermogenesis Mapping

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00434B, Paper

Ronak Lazarus, Rupal Kothari, Venkata Vamsi Krishna Venuganti, Amit Nag
Temperature dynamics in living cells provide critical insights into metabolic processes and cellular energy pathways. However, precise intracellular thermometry to measure minimal temperature fluctuations, typically 0.1°C -0.2°C change in the...
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Ultrasensitive, simultaneous detection of two biomarkers with a localized surface plasmon resonance biosensor

Analyst, 2026, Accepted Manuscript
DOI: 10.1039/D6AN00483K, Paper

Wenyu Xu, Yuanfu Zhang, Yaqi Liu, Lekai Li, Xianfeng Shao, Xueru Chen, Xinzhi Li, Xianxi Zhang, Federico Rosei
A localized surface plasmon resonance (LSPR) biosensor was developed for the simultaneous detection of two components, namely telomerase and fibrin, based on the impact of single-stranded DNA (ssDNA) length on...
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Differentiation of disaccharide isomers via diagnostic-ion-weighted spectral library searching using data from tandem MS analysis of chloride adducts

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00268D, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Shixiang Xu, Santosh R. Acharya, Ruth M. Speidel, Abraham K. Badu-Tawiah
Chloride adducts of rare sugars enable diagnostic fragment ions to be generated in tandem MS, allowing a highly specific algorithm to be developed to differentiate isomers of rare sugars.
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Synergistic peroxidase-like activity of the Cu–Zn MOF-incorporated g-C3N4 nanozyme integrated with a smartphone-based colorimetric sensor for ciprofloxacin detection

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00320F, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Surendhar Sasikumar, Arunjegan Amalraj, Panneerselvam Perumal
Graphical representation of Cu-Zn-MOF/g-C₃N₄ for ciprofloxacin detection.
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Charge-tunable hemicyanine probes for bacterial imaging and bacterial infection tracking

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00336B, Paper

Kunyi Wang, Yiyang Wang, Wenbo Zhu, Lebin Wang, Zixuan Zhang, Boyaxuan Chen, Wenbo Luo, Xuefei Wang, Zhuo Wang
Charge-tunable hemicyanine probes enable selective imaging of Gram-positive and Gram-negative bacteria, real-time tracking of bacterial infection in host cells, and long-term imaging in complex biological fluids.
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Cyclic cataluminescence method enabled by a heterogeneous electron allocator for multiple-aldehyde detection in tea

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00170J, Paper

Huiting Chen, Mengmeng Ji, Ling Xia, Yufei Hu, Gongke Li
Cyclic chemiluminescence method enabled by a heterogeneous electron allocator for the detection of multiple aldehydes in tea.
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Biochemical composition of prostate core-needle biopsies before and after a single fraction of 13.5 Gy: a Raman spectroscopy-based study

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00128A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Kirsty Milligan, Mitchell Wiebe, Alejandra Fuentes, Sandra Popescu, Ramie Ali-Adeeb, Jeffrey Andrews, Julian Lum, Alexandre Brolo, Christina Haston, Bibi Naghibi Torbati, Juanita Crook, Andrew Jirasek
Raman spectroscopy for analysis and characterisation of patient biopsy response to brachytherapy. Carotenoids are found to play a significant role in response dynamics as observed via Raman spectroscopy.
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Lipidomic signatures of CNS ischemic injury and their modulation by immunomodulatory hydrogels

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00089D, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Mary F. Wang, Yunxin Ouyang, Tatiana Segura, David C. Muddiman
Ischemic injury in the central nervous system (CNS) triggers profound metabolic remodeling that influences inflammation, repair, and cellular survival.
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Identification of volatile organic compound markers for bacterial growth in spacecraft wastewater

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00060F, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Sarah Kingsley, Hang N. Nguyen, Aaron N. Knopp, Christian L. Castro, Thomas M. Orlando, Sarah L. Castro-Wallace, William T. Wallace
This work presents proof of concept for an MS-based technique for the detection of common spacecraft bacteria in spacecraft wastewater.
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One-step digestion–ligation–activation universal strategy for ultrasensitive detection of DNA methylation

Analyst, 2026, Advance Article
DOI: 10.1039/D5AN01270H, Paper

Shiying Zhou, Tao Gu, Liyuan Deng, Xianfeng Wang, Shuyu Zhu, Xinyu He, Mei Yang, Danqun Huo, Changjun Hou
A digestion–ligation–activation strategy integrates methylation-dependent restriction, RLAMP amplification, and CRISPR/Cas12a trans-cleavage into a one-pot cascade for ultrasensitive DNA methylation and methyltransferase analysis.
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A portable acoustic biosensing platform combined with paper-based capillary fluidics for the rapid detection of antibodies in serum

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00114A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Dimitra Chronaki, Stylianos Grammatikos, Angelos Ntimtsas, Marios Matsis, Orestis F. Kokolakis, Konstantina Alexaki, Zoi Pournara, Achilleas Tsortos, Alexandros Zafiropoulos, Electra Gizeli
We report the development of a sensitive biosensing platform based on a shear-horizontal surface acoustic wave (SH-SAW) device and paper fluidics, with the potential to be used outside centralized laboratory settings.
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A digital microfluidic integrated SiNW array FET for amplification-free detection of extracellular vesicle-derived miRNAs

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00306K, Paper

Rui Jiang, Jiaqi Guo, Zizhen Wang, Jun Cheng, Han Zhang, Qingzhu Zhang, Lingqian Zhang, Yang Zhao, Chengjun Huang, Mingxiao Li
An integrated DropFET device combining a high-density active-matrix digital microfluidic chip with a silicon nanowire array field-effect transistor sensor enables sample pretreatment and highly sensitive detection of EV–miRNAs.
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Electrochemical determination of nitrofurantoin using a self-templated NiFeCo layered double oxide-carbon composite with dynamic Fe regeneration

Analyst, 2026, Advance Article
DOI: 10.1039/D6AN00347H, Paper

Jiang-Tao Chen, Ming-Dong Wang, Fen-Ying Kong, Tian-Pei Cai, Lu-Mei Wang, Juan-Juan Gao, Wei Wang
A NiFeCo layered double oxide supported N,S co-doped collagen-derived porous carbon (NiFeCo LDO-C) enables trace-level electrochemical detection of nitrofurantoin via dynamic metal active-site regeneration and self-template/self-etching strategy.
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Surface-enhanced Raman spectroscopy for comprehensive urinalysis: advances, challenges, and clinical perspectives

Analyst, 2026, 151,2747-2762
DOI: 10.1039/D6AN00201C, Tutorial Review

Si Chen, Yuemei Chen, Yuxin Liu, Chunying Zhang, Jianke Yang, Xiaoqin Xu, Tonghao Zhang, Yali Song, Tingting Zeng
Urine, a noninvasive, information-rich biofluid, reflects systemic and urological physiology via metabolites, biomarkers, and drug residues. SERS enables rapid, sensitive, label-free molecular profiling, supporting potential clinical applications.
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A two-point fluorescence detection flow cell with empirical calibration for high optical density analysis

Analyst, 2026, 151,2767-2772
DOI: 10.1039/D6AN00106H, Communication

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Tin Weitner, Davor Šakić
A dual-detector fluorescence flow cell with software calibration enables accurate quantification at previously inaccessible high optical densities.
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Analysis of cholesterol-induced mechanical modulation of cell membranes by nanopipette-generated fluid flow

Analyst, 2026, 151,2763-2766
DOI: 10.1039/D6AN00067C, Communication

Shu-Yue Xu, Meng-Qi Zhao, Xin-Yue Liu, Ming-Jie Ye, Bin-Bin Chen, Da-Wei Li, Mahmoud Elsayed Hafez, Jian Lv, Ruo-Can Qian
A label-free membrane oscillation strategy based on nanopipette-generated fluid flow to investigate cholesterol-induced mechanical alterations in living cell membranes.
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A metaproteomic platform for integrated host-pathogen-microbiota profiling in zebrafish larvae

Analyst, 2026, 151,2773-2780
DOI: 10.1039/D6AN00088F, Communication

Javiera Ortiz-Severín, Antonia Ramos-Guzmán, Ian Pérez, Miguel L. Allende, Francisco P. Chávez
Understanding host–pathogen–microbiota interactions requires analytical strategies capable of resolving multiple biological compartments within a single experimental framework.
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Time-domain luminescence lifetime imaging with oxygen sensor particles in the presence of actinic light

Analyst, 2026, 151,2800-2809
DOI: 10.1039/D6AN00122J, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Georg Schwendt, Michael Kühl
Fast and robust oxygen imaging under photon irradiance levels corresponding to mid-day solar irradiation.
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Design of a “turn-on” colorimetric sensor for AChE inhibitors based on the instability of metal–organic frameworks

Analyst, 2026, 151,2995-3003
DOI: 10.1039/D6AN00156D, Paper

Jun Zhang, Wenzhu Jiang, Zhiping Xu, Lin Zhang
Illustration of the colorimetric assay based on Cu-BTC with peroxidase-like activity for the AChE inhibitor.
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Disentangling method-induced differences in metabolomics: single- versus dual-phase extraction

Analyst, 2026, 151,2842-2851
DOI: 10.1039/D6AN00025H, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Sehyeon (Erica) Kim, Tao Huan
A systematic LC-MS metabolomics comparison reveals how pipetting, partitioning, and matrix effects drive differences between single- and dual-phase extractions, providing a framework for optimizing metabolite recovery and analytical performance.
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The infinite-dimensional nature of spectroscopy and why models succeed, fail, and mislead

Analyst, 2026, 151,2978-2994
DOI: 10.1039/D6AN00346J, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Umberto Michelucci, Francesca Venturini
Machine learning (ML) models have achieved high accuracies in spectroscopic classification, without a clear proof that those models used chemical features. High dimensionality offers a shortcut for models to achieve the performance we observe.
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Flavourings, nicotine content, and elemental composition as indicators of regulatory compliance in nicotine pouches and heated tobacco products

Analyst, 2026, 151,2962-2977
DOI: 10.1039/D6AN00153J, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Matjaž Rantaša, Matjaž Finšgar
Nicotine pouches (NPs) and heated tobacco products using heatsticks (HSs) are relatively new alternatives to traditional smoking.
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Se-, S-, and N-doped carbon dot-based AuNPs for the detection of 6-methylnicotine in e-cigarettes by surface-enhanced Raman scattering

Analyst, 2026, 151,2907-2916
DOI: 10.1039/D5AN01296A, Paper

Zhao Zhao, Qianqian Pang, Xi Wang, Zhichao Chen, Xianfang Rong, Yaling Yang
Using S-, Se-, N-doped carbon dots, SERS-active gold nanoparticles were prepared. A sensitive sensor for 6-methyl nicotine in e-cigarettes was established via specific S-Au/Se-Au/N-Au interactions, with a detection limit of 0.13 μg L⁻¹.
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Shell-switchable SERS blocking strategy for quantitative copper ion detection using single-particle SERS probes

Analyst, 2026, 151,2810-2817
DOI: 10.1039/D6AN00174B, Paper

Longteng Liang, Yingqing Zhu, Anran Wang, Lixia Li, Ning Feng, Yufang Liu
A shell-switchable SERS blocking strategy using single-particle probes enables accurate Cu²⁺ quantification via oxidative etching-mediated Raman intensity regulation.
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Predictive analysis of organic semiconductor photodegradation by FTIR spectroscopy with multivariate analysis

Analyst, 2026, 151,2858-2867
DOI: 10.1039/D5AN01007A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Sarah M. Tyler, Thomas J. Blackburn, Kellen T. Schneider, Jeanne E. Pemberton
Evaluation of ATR-FTIR as a predictive tool for characterizing organic semiconductor degradation is discussed. Accurate classification of degradation is demonstrated with multivariate analysis tools.
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Bacterial imprinted polymer-based detection of Escherichia coli using polydopamine on gold nanodendrite/graphene oxide modified electrodes

Analyst, 2026, 151,2831-2841
DOI: 10.1039/D5AN01217A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Yilei Xue, Jessica Chen, Meissam Noroozifar, Ruby May A. Sullan, Kagan Kerman
An electrochemical biosensor based on a glassy carbon electrode modified with graphene oxide, gold nanodendrites, and polydopamine was developed with Escherichia coli imprinted on the surface.
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Environmentally benign synthesis of blue fluorescent graphene quantum dots for nitroaromatic sensing (p-nitroaniline and 2,4,6-trinitrophenol) and their nanophytotoxicity analysis

Analyst, 2026, 151,2888-2906
DOI: 10.1039/D6AN00045B, Paper

Krishna Moni Deka, Saikat Das, Rachita Newar, Rajkanya Das, Bappy Sen, Hemen Sarma, Arabinda Baruah
Blue fluorescent graphene quantum dots for nitroaromatic sensing (p-nitroaniline and 2,4,6-trinitrophenol) and analysis of their nanophytotoxicity.
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In situ growth of Pd nanoparticles on wood for highly sensitive hydrogen sensing

Analyst, 2026, 151,2917-2926
DOI: 10.1039/D6AN00185H, Paper

Wanli Lin, Ming Li, Zechun Li, Shaojin Shi, Changkun Zhu, Jun Yan, Ying Chen, Pengcheng Xu, Xinxin Li
In situ growth of Pd nanoparticles on wood as a catalyst for developing a highly sensitive MEMS thermopile H₂ sensor.
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Metal–organic framework-based molecularly imprinted polymers for the dispersive solid-phase extraction of fluoroquinolones in coastal zone water and biological samples

Analyst, 2026, 151,2818-2830
DOI: 10.1039/D6AN00241B, Paper

Jingying Huang, Jingyi Yan, Mingsan Man, Saqib Farooq, Zihan Qiu, Shuai Wu, Liangwei Zhang, Lingxin Chen, Jinhua Li
MOF-MIPs-based DSPE coupled with HPLC–UV was developed as a strategy for the simultaneous determination of six FQs in coastal zone water and biological samples.
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Thiol–phenolic interactions in electropolymerized methimazole enable superior isomer discrimination for hydroquinone and catechol sensing

Analyst, 2026, 151,2951-2961
DOI: 10.1039/D6AN00061D, Paper

Dexian Kong, Jiajin Feng, Shiting Deng, Mingwei Yang, Yuwu Chi
A new electropolymerized methimazole (p-MMI) film-modified glassy carbon electrode was developed for simultaneous detection of hydroquinone (HQ) and catechol (CC).
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A nickel-based bipolar electrochemiluminescence platform for glucose detection

Analyst, 2026, 151,2852-2857
DOI: 10.1039/D6AN00092D, Paper

Xianchuan Dong, Yaoxuan Wang, Jing Sui, Siqi Huang, Feifei Zhang, Zonghua Wang
This study describes a 10-channel bipolar ECL sensing device employing nickel as the electrode material for the sensitive detection of glucose in human urine. The device can be powered by two commercially available AA batteries.
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Portable and point-of-care molecular detection of pathogenic Vibrio parahaemolyticus in shrimp

Analyst, 2026, 151,2791-2799
DOI: 10.1039/D6AN00099A, Paper

Thi Ngoc Diep Trinh, Kieu The Loan Trinh, Hanh An Nguyen, Huynh Minh Triet Nguyen, Nguyen Thi Hong Nhi, Vo Thi Tuyet Minh, Nguyen Nhat Nam, Nae Yoon Lee
A portable and fully-integrated point-of-care molecular diagnostic device detecting pathogenic Vibrio parahaemolyticus carrying pirA gene which causes Acute Hepatopancreatic Necrosis Disease in shrimp is developed.
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An ultra-sensitive photoelectrochemical aptasensor based on a CdIn2S4/ZnSnO3 composite for the detection of adenosine triphosphate

Analyst, 2026, 151,2879-2887
DOI: 10.1039/D6AN00158K, Paper

Ling Zhang, Lu-Ying Wang, Yu-Ping Wei, Jing-Shuai Chen, Hui Zhu, Xing-Pei Liu, Chang-Jie Mao, Bao-Kang Jin
We present a highly sensitive PEC aptasensor for ATP detection based on CIS/ZSO heterojunction and nanozyme-catalyzed precipitation amplification.The sensor exhibits excellent stability, selectivity and potential for serum ATP analysis.
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Quantitative analysis of colorimetric hydrogel/paper mini-disk arrays using a handheld Wi-Fi scanner

Analyst, 2026, 151,2868-2878
DOI: 10.1039/D6AN00255B, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Lin Qi, Pitipat Parittothok, Sophia Sun, Jakrapop Wongwiwat, Aluck Thipayarat, Wanida Laiwattanapaisal, Hua-Zhong Yu
A point-of-need analytical protocol for quantitative colormetric assays by integrating hydrogel-paper mini-disks, a handheld scanner, and a custom-designed app.
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