RSC - RSC Mechanochem. latest articles

Liquid-assisted ball-milling synthesis of organic carbonates as aroma compounds

RSC Mechanochem., 2026, Advance Article
DOI: 10.1039/D6MR00048G, Paper

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Can Bozdemir, Mehmet Efe Çelik, Mehmet Mart, Aydın Alemdar, Ahmet Baydar, Cagatay Dengiz
This manuscript explores the synthesis of aroma compounds using a solvent-free ball milling method, yielding nine new carbonate compounds. This approach offers an alternative to traditional methods, eliminating the use of low-odor-threshold bases.
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Moving mechanochemistry forward: tribochemistry

RSC Mechanochem., 2026, Advance Article
DOI: 10.1039/D6MR90014C, Editorial

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James Batteas, Wilfred Tysoe, Judith A. Harrison
Editor-in-Chief James Batteas, Wilfred Tysoe and Judith A. Harrison examine important advances in tribochemistry.
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Outstanding Reviewers for RSC Mechanochemistry in 2025

RSC Mechanochem., 2026, Advance Article
DOI: 10.1039/D6MR90015A, Editorial

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We would like to take this opportunity to highlight the Outstanding Reviewers for RSC Mechanochemistry in 2025, as selected by the editorial team for their significant contribution to the journal.
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Energy-efficient mechanochemical synthesis of MgWO4 phase materials: (micro)-structural, thermal, and optical properties

RSC Mechanochem., 2026, Advance Article
DOI: 10.1039/D6MR00044D, Paper

Open Access

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S. A. Ashika, S. Balamurugan
A simple, energy-efficient mechanochemical milling method for achieving phase formation of monoclinic MgWO₄ materials using a mixture of MgO and WO₃ without the need for additional thermal treatment.
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One-sequence mechanochemical synthesis-deracemisation of a levetiracetam intermediate

RSC Mechanochem., 2026, Advance Article
DOI: 10.1039/D6MR00053C, Paper

Open Access

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Guillaume Wery, Tom Leyssens
Mechanochemistry allows for a one-sequence synthesis-deracemization process for the synthesis of an enantioenriched intermediate of levetiracetam.
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Unlocking the reversibility of the mechanochemical synthesis of a pharmaceutical cocrystal

RSC Mechanochem., 2026, Accepted Manuscript
DOI: 10.1039/D6MR00052E, Paper

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Artem Golomolzin, Evgeniy A. Losev, Elena Boldyreva
Opposite transformations (synthesis or decomposition of the cocrystal) in the system “piroxicam (P) – succinic acid (S) – their 2:1 cocrystal (P2S)” are documented depending on the protocol of mechanical...
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Resonant acoustic mixing-induced polymorphic transformation of glycine observed by solid-state NMR

RSC Mechanochem., 2026, Advance Article
DOI: 10.1039/D6MR00055J, Communication

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Simon Sinn, Elizabeth Brown, Téodor Iftemie, David L. Bryce
Carbon-13 magic-angle spinning solid-state NMR is used to monitor the real-time resonant acoustic mixing-induced polymorphic transformation of α-glycine to γ-glycine. Stepped JMAK kinetics are found to depend on the RAM vial filling factor.
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When breaking heterojunctions unlocks a reactive compromise in photomechanocatalytic phenol degradation over P25-TiO2

RSC Mechanochem., 2026, Advance Article
DOI: 10.1039/D6MR00034G, Paper

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Guillaume Demily, Nicolas Kania, Anne Ponchel, Stéphane Menuel
Mechanical activation disrupts TiO₂ heterojunctions, unlocking dark oxidative reactivity while compromising optimal UV photocatalysis, establishing a reactive compromise for sustainable environmental remediation.
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Mechanistic insights into mechanochemical oxidation of 1,1-disubstituted alkenes mediated by polymer-derived mechanoradicals

RSC Mechanochem., 2026, Advance Article
DOI: 10.1039/D6MR00040A, Paper

Open Access

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Akira Kodaka, Takumi Yamamoto, Hajime Sugita, Akira Takahashi, Hideyuki Otsuka
Mechanochemical polymer radicals enable solvent-free oxidative cleavage of 1,1-disubstituted alkenes using molecular oxygen in the solid state.
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Making and breaking Si–Si bonds under mechanochemical conditions

RSC Mechanochem., 2026, Advance Article
DOI: 10.1039/D6MR00024J, Paper

Open Access

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Thomas Lainer, Michael Haas
Mechanochemistry offers a sustainable alternative to solution-based synthesis, yet its potential in main-group chemistry remains largely untapped.
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Interfacial mechano-nanoarchitectonics for chemical, materials and biological processes

RSC Mechanochem., 2026, Advance Article
DOI: 10.1039/D5MR00134J, Review Article

Open Access

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Katsuhiko Ariga
This review discusses interfacial mechano-nanoarchitectonics in chemical, materials and biological processes, suggesting that interfaces are essential for combining mechanical manipulation of functional material systems with nanoarchitectonics.
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Sonochemistry- and mechanochemistry-driven one-pot synthesis of polyfunctionalised 5-iodo-1H-1,2,3-triazoles through copper(I)-catalysed click chemistry

RSC Mechanochem., 2026, Advance Article
DOI: 10.1039/D6MR00036C, Paper

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Koushik Pal, Pintu Karmakar, Goutam Brahmachari
Straightforward, rapid, and practical alternative dual synthetic strategies to access 5-iodo-1H-1,2,3-triazoles, using ultrasound and a high-speed ball mill as green energy tools.
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Mechanochemistry-directed ligand design for enhanced reactivity and enantioselectivity in solve-less palladium-catalyzed conjugate arylations

RSC Mechanochem., 2026, Advance Article
DOI: 10.1039/D6MR00032K, Paper

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Keisuke Kondo, Hina Shoji, Koji Kubota, Hajime Ito
We have developed the first mechanochemical protocol for a solvent-less palladium-catalyzed conjugate arylation, which was enabled by designing new mechanochemistry-directed bipyridine and chiral pyridine–oxazoline ligands.
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Amano-PS-IM-catalyzed mechanochemical enzymatic acylative kinetic resolution of secondary alcohols

RSC Mechanochem., 2026, Advance Article
DOI: 10.1039/D6MR00028B, Paper

Open Access

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Koji Kubota, Yuri Kamakura, Taiga Takeda, Hajime Ito
An appropriate choice of milling conditions as well as a liquid-assisted grinding additive enable the Amano-PS-IM-catalyzed highly efficient acylative kinetic resolution of secondary alcohols under mechanochemical conditions.
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