RSC - Nat. Prod. Rep. latest articles

Hot off the press

Nat. Prod. Rep., 2013, 30,760-764
DOI: 10.1039/C3NP90015K, Hot off the Press Article

Robert A. Hill, Andrew Sutherland
A personal selection of 33 recent papers is presented covering various aspects of current developments in bioorganic chemistry and novel natural products such as asperterpenoid A, a metabolite of an endophytic Aspergillus species.
The content of this RSS Feed (c) The Royal Society of Chemistry

Glucuronides from metabolites to medicines: a survey of the in vivo generation, chemical synthesis and properties of glucuronides

Nat. Prod. Rep., 2013, 30,806-848
DOI: 10.1039/C3NP70003H, Review Article

Andrew V. Stachulski, Xiaoli Meng
Glucuronides have long been known as important phase 2 metabolites of drug molecules. Here we review and update the biogenesis, chemical synthesis and bio-medicinal chemistry of glucuronides, including their potential as drugs and pro-drugs and their interaction with biomolecules.
The content of this RSS Feed (c) The Royal Society of Chemistry

Muscarine, imidaozle, oxazole and thiazole alkaloids

Nat. Prod. Rep., 2013, 30,869-915
DOI: 10.1039/C3NP70006B, Review Article

Zhong Jin
This review summarizes the latest progress on the isolation, identification, biological activities, and chemical synthesis of these NPs with a literature coverage from July 2010 to June 2012.
The content of this RSS Feed (c) The Royal Society of Chemistry

Amaryllidaceae and Sceletium alkaloids

Nat. Prod. Rep., 2013, 30,849-868
DOI: 10.1039/C3NP70005D, Review Article

Zhong Jin
This review summarizes the latest progress on the isolation, biological activity, and chemistry of naturally occurring alkaloids from plants of the Amaryllidaceae family and the structurally closely related Sceletium species.
The content of this RSS Feed (c) The Royal Society of Chemistry

Marine natural products: synthetic aspects

Nat. Prod. Rep., 2013, 30,783-805
DOI: 10.1039/C3NP20116C, Review Article

Jonathan C. Morris
An overview of marine natural products synthesis during 2010 is provided.
The content of this RSS Feed (c) The Royal Society of Chemistry

Hirsutellones and beyond: figuring out the biological and synthetic logics toward chemical complexity in fungal PKS-NRPS compounds

Nat. Prod. Rep., 2013, 30,765-782
DOI: 10.1039/C3NP70016J, Review Article

Xu-Wen Li, Alexandre Ear, Bastien Nay
Have a game! Biosynthetic functionalization can trigger a highly reactive intermediate favourable to cyclization. In this case, the cyclization may be activated by an oxidation of the blue polyketide moiety of the top linear precursor.
The content of this RSS Feed (c) The Royal Society of Chemistry