RSC - J. Mater. Chem. B latest articles

Impact of Phospholipase A2 hydrolysis on Triplet-Triplet Annihilation Upconversion Liposomes

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00152A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Amrutha Prabhakaran, Nirod Kumar Sarangi, Colm Smith, Ruben Arturo Arellano-Reyes, Tia E. Keyes
Triplet-triplet annihilation upconverting (TTA-UC) liposomes are of emerging interest because of their potential bioapplications in biosensing/imaging and light driven therapeutic delivery. However, a potential challenge in-vivo is their stability, since...
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Extracellular Vesicle-Integrated Gelatin Sponges Enhance Angiogenesis and Cell Migration in Wound Healing

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00705H, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Elif Conger Onder, Şükrü Öztürk, Naside Mangir, Alp Can, Kezban Ulubayram
Wound healing remains a major global burden on healthcare systems. Extracellular vesicles (EVs)-based therapies have emerged as promising cell free approaches due to their ability to deliver bioactive cargo. However,...
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Localised Al(OH)3 Quantum Dot Passivation for Safe-by-Design Rutile TiO2 Nanomaterials for UV Protection

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00995F, Paper

Bulathsinhalage Nuwangi Pramuditha Nuwangi Pramuditha Cooray, Rajib Das, Philip Barker, Michael Lerch, Konstantin Konstantinov
Titanium dioxide (TiO2) is a cornerstone UV-filtering material, yet its intrinsic photocatalytic activity continues to raise concerns regarding safety and photostability in cosmetic applications. Here, we introduce a quantum-dot (QD)...
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Cucumber-derived exosome-like nanovesicles encapsulating epigallocatechin gallate for skin depigmentation: molecular docking, stability, and efficacy in B16/F10 cells and zebrafish

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00396F, Paper

Li Tao, Ping Wang, Mengying Zhang, Wenyue Zhang, Rui Zhang, Junhao Tao, Mingyuan Chen, Jing Wu, Kawagishi Hirokazu, Peishi Feng
To address the challenges of instability and low bioavailability that limit the application of (−)-epigallocatechin gallate (EGCG) as a whitening agent, we engineered a cucumber-derived exosome-like nanovesicle (CEV) as a synergistic nanocarrier.
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Trimetallic nano trap-mediated glycolytic and mitochondrial metabolism co-inhibition: ATP suppression for enhanced metal ion-interference therapy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00216A, Paper

Qingqing Wang, Kun Yan, Lin Zhu, Jiaxin Li, Sen Li, Yiyan Miao, Yansong Shen, Lei Cao, Haijiao Chen, Guiping Yu, Dihai Gu
Mitochondria serve as central regulators of tumorigenesis, progression, metastasis, and chemoresistance, playing a pivotal role in cancer bioenergetics and thus representing prime targets for anticancer therapy.
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Vibration-Controlled Extrusion-Based 3D Printing of Graphene-Hydroxyapatite Scaffolds: Structural, Mechanical, and Electrical Insights

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00755D, Paper

Mohammad R. Dalir Abdollahinia, milad karimi, Amir M Ruiin, Hassan Nosrati
This study presents a comprehensive investigation into the effects of nonlinear vibrational regimes on the structural and functional integrity of reduced graphene oxide-hydroxyapatite (rGO-HA) scaffolds fabricated via extrusion-based 3D-printing. A...
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Ethanol-Responsive Fluorene-based Fluorescent Nanoprobes for Photodynamic Cancer Therapy

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00469E, Paper

Vaishnavi Mekkeparambath, Pragya Trivedi, M. M. Sreejaya, Reshmi C, Ananya Kannamvelli Illam, Lina Anil Kumar, Avijit Jana, Pattath D Pancharatna, Moumita Gangopadhyay
Ethanol-responsive fluorophores represent a promising tool for early diagnosis of selected cancers owing to ethanol accumulation within cancer cells due to Warburg effect. Herein, we report a series of fluorene-based...
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Hepatocyte purification column using thermoresponsive glycopolymer-modified silica beads

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00422A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Kenichi Nagase, Junnosuke Matsuda
Thermoresponsive glycopolymer brush modified beads were fabricated via silane coupling reaction and subsequent tandem ATRP. The column packed with these beads can facilitate hepatocyte separation with the help of temperature modulation.
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Fabrication of a hybrid cellularized cardiac patch via 3D bioprinting of alginate-gelatin-PEOz patterns on electrospun PLCL-PEOz nanofibers

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00103C, Paper

Muthu Parkkavi Sekar, David Raj Chellappan, Dhakshinamoorthy Sundaramurthi, Swaminathan Sethuraman
Integrating electrospinning & 3D bioprinting to biofabricate 3D cellular cardiac patches with topographical and cellular cues for improved cardiac regeneration.
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Injectable VEGF-loaded gelatin–hyaluronic acid hydrogel to synergistically promote flap survival via rapid angiogenesis

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00255B, Paper

Dan Zhong, Lin Zhi, Haitao Xiao, Xuewen Xu
A vascular endothelial growth factor (VEGF)-loaded injectable hydrogel composed of gelatin and low-molecular-weight hyaluronic acid synergistically promotes angiogenesis and improves the skin flap survival rate.
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A stimuli-responsive gradient-structured membrane for dual controlled release of bioactive agents: application to chronic wound dressings

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02922H, Paper

D'orgevale Chobli, Katia Maria Pérez Andeliz, Sébastien Massier, Louise Hespel, Stephane Marais, Anthony Christopher Duncan
This article describes the elaboration of an original polymeric membrane for wound dressing applications. Currently, asymmetric polymeric membranes exhibit numerous advantages such applications. Usually, numerous systems allow the release of...
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Correction: Matrix-bound Tenascin-C directs neuronal differentiation through stiffness-tuned MeHA hydrogels mimicking the spinal cord microenvironment

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB90072K, Correction

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Rounak Pokharel, Vasanti Dhakate, Jessica Onyak, Elif Ertugral, Chandrasekhar R. Kothapalli, Nic D. Leipzig
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A specific fluorescent probe for detecting endogenous butyrylcholinesterase: multi-model validation from cells to zebrafish and type 2 diabetes mellitus mice

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00541A, Paper

Zhipeng Chen, Ling Huang, Qingqing Ma, Weiying Lin
We designed and synthesized the new fluorescent probe YNP for detecting endogenous butyrylcholinesterase and validated it across multiple models ranging from cells to zebrafish and type 2 diabetic mellitus mice.
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Unimolecular micelles as an effective carrier of poorly water-soluble nifuratel for selective in vivo anticervical cancer therapy via mucoadhesive dynamic hydrogels

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00746E, Paper

Monika Gosecka, Mateusz Gosecki, Malgorzata Urbaniak, Ewelina Wielgus, Renata Gruszka, Monika Marcinkowska, Barbara Klajnert-Maculewicz, Anna Janaszewska
Cervical cancer remains a significant global health challenge, accounting for over 340,000 deaths annually. Consequently, there is an urgent need for localized drug delivery systems that can effectively eradicate cancer...
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High-Specificity Kilobase-Level Multiplex PCR Enabled by Graphene Oxide-Dendrimer-Encapsulated Gold Nanoparticles

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00032K, Paper

Dongqing Zhao, Yao Lu, Huanhuan Zong, Yuxin Tang, Chen Tang, Meng Lu, yuxun zhou, Kai Li, Junhua Xiao
To address the challenges of nonspecific amplification in kilobase (kb)-level multiplex polymerase chain reaction (PCR), we developed an innovative nanomaterial—graphene oxide-dendrimer-encapsulated gold nanoparticles (GO-G3-Au). This material achieves high amplification specificity...
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A cucurbit[7]uril-based upconversion nanoplatform for targeted photodynamic drug delivery

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00884D, Communication

Dandan He, Zongze Duan, Guizhao Shen, Ting Liu, Simin Liu, Zhiyong Zhao
A CB[7]-mediated upconversion nanoplatform co-delivers the aptamer complex AS1411-C15/Hemin and photosensitizer porphyrin to achieve a cascade reaction for enhanced photodynamic therapy.
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Research progress and interfacial adhesion mechanisms of oral delivery systems based on natural polymers

J. Mater. Chem. B, 2026, 14,6179-6201
DOI: 10.1039/D6TB00109B, Review Article

Di Zhao, Zhujun He, Yue Chen, Bojun Zhou, Yali Zhu, Zhibin Li, Zuobing Xiao, Yunwei Niu, Yamei Wang
Oral mucoadhesive delivery is a significant strategy for drug administration due to its capacity to bypass hepatic first-pass metabolism and enhance drug bioavailability.
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Stem cell-derived nanovesicles delivered by responsive hydrogels for refractory wound therapy

J. Mater. Chem. B, 2026, 14,6156-6178
DOI: 10.1039/D5TB02658J, Review Article

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Meijiao Zhao, Genghong Guo, Ronghua Yang, Jie Fang, Xiaoping Zhong, Xueshan Xia, Xu Chen, Yuhui Liao
This review summarizes the complex pathological microenvironment of refractory wounds, tissue-regenerative mechanisms of stem cell-derived nanovesicles (SC-NVs), smart hydrogel-based delivery systems, and clinical challenges and prospects.
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Modulating oxidative stress and bacterial infection with carbon dot-infused bioactive hydrogels for infected wound regeneration

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00424E, Paper

Ananya Mohanty, Kushal Johri, Arindam Pramanik, Sasmita Mohapatra
A carbon dot-integrated hydrogel (CD@PG-PD) accelerated wound healing by integrating antioxidant, antibacterial, and hemostatic functions and promoting cell migration in a rat model.
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Nonionic peptide amphiphiles and their supramolecular co-assemblies tune charge density and bioactivity

J. Mater. Chem. B, 2026, 14,6252-6261
DOI: 10.1039/D6TB00293E, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Jacob A. Lewis, Ronit Freeman, Tristan D. Clemons, Jacqueline M. Godbe, Nicholas Stephanopoulos, Samuel I. Stupp
Supramolecular peptide assemblies generally rely on ionic groups for solubility in aqueous media but charge may sometimes affect their biological functions.
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In situ engineered selenium nanoparticles enable multifunctional PLA mixed matrix membranes with potential for hemodialysis

J. Mater. Chem. B, 2026, 14,6397-6418
DOI: 10.1039/D6TB00354K, Paper

Aleksandra Domke, Mariusz Jancelewicz, Tomasz Szymański, Marcin Jarek, Jakub Rybka, Szymon Mania, Adrianna Banach-Kopeć, Zuzanna Buchwald, Mariusz Sandomierski, Maria Ratajczak, Marcel Jakubowski, Marta Woźniak-Budych, Katarzyna Staszak
PLA/PEG mixed matrix membranes with in situ engineered Se nanoparticles show enhanced antifouling, antibacterial activity, and hemocompatibility, offering promising performance for advanced hemodialysis applications.
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Dictated cell adhesion and migration using microfluidic-controlled synthetic hydrogels exhibiting programmable viscoelasticities

J. Mater. Chem. B, 2026, 14,6237-6251
DOI: 10.1039/D6TB00438E, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Haochen Yang, Ziyuan Li, Gilad Davidson-Rozenfeld, Meng Li, Yuxing Shang, Linjie Chen, Yingchao Ma, Yifan Ge, Itamar Willner, Junji Zhang
Cell adhesion, migration, and separation are dictated by mechanosensing substrates exhibiting gradient viscoelasticities.
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Perfluoroalkylated amphiphilic porphyrin nanomicelles for improved photodynamic therapy: anti-tumour efficacy through stability enhancement and O2 enrichment

J. Mater. Chem. B, 2026, 14,6355-6363
DOI: 10.1039/D6TB00359A, Paper

Dan-Wei Zhang, Danying Ma, Congying Guo, Zhuo Lei, Yajie Zhu, Rui Gao, Hui Wang, Jia Tian, Wei Zhou, Zhan-Ting Li
Perfluoroalkyl chains form a fluorocarbon microphase that stabilizes nanomicelles assembled with a trianionic porphyrin amphiphile and enriches O₂ in the nanomicelles, leading to the enhancement of photodynamic activity.
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Molecular engineering of B/N substituents in asymmetrical salicylaldimine-based boranils for tuning solid-state emission and cellular lipid-droplet imaging

J. Mater. Chem. B, 2026, 14,6262-6269
DOI: 10.1039/D6TB00747C, Paper

Xiaoyan Gao, Mingyue Cao, Jie Huang, Haiyang Yu, Zhiqiang Liu, Xiaoqiang Yu
A series of fluorescent asymmetrical BFPh-bridged boranil derivatives were synthesized. They exhibit strong solid state emission, near-unity quantum yields in solution, and potential for cellular lipid droplet imaging.
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Matrix-bound Tenascin-C directs neuronal differentiation through stiffness-tuned MeHA hydrogels mimicking the spinal cord microenvironment

J. Mater. Chem. B, 2026, 14,6419-6434
DOI: 10.1039/D6TB00247A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Rounak Pokharel, Vasanti Dhakate, Jessica Onyak, Elif Ertugral, Chandrasekhar R. Kothapalli, Nic D. Leipzig
Matrix-bound Tenascin-C, presented in stiffness-matched hyaluronic acid hydrogels mimicking the spinal cord microenvironment, selectively promotes neuronal and motor neuron differentiation through a concentration-dependent bioactive window.
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Dual-function hydrogel microspheres coordinate immune regulation and osteogenesis coupling to promote femoral regeneration

J. Mater. Chem. B, 2026, 14,6377-6396
DOI: 10.1039/D5TB02399H, Paper

Lingjun Wang, Zhengxia Ni, Yiyang Huang, Jiannan Mao, Jie Wu, Wei Wang, Xinzhao Jiang, Liang Zhou, Jincheng Tang, Kun Xi, Yong Gu, Liang Chen
The preparation process of dual-functional hydrogel microspheres and their mechanism of action in promoting femoral regeneration through coordinated immunomodulation and osteogenic coupling.
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Easy access to 2,1,3-benzothiadiazole-based symmetric deep red-AIEgens for concurrent staining of lipid droplets and lysosomes

J. Mater. Chem. B, 2026, 14,6282-6297
DOI: 10.1039/D6TB00360E, Paper

Shivani Tripathi, Harshala Patil, V. Vamsi Krishna Venuganti, Manab Chakravarty
We present new deep red-emissive benzothiadiazole-based AIEgens as easily accessible, stable organic dyes that simultaneously stain lipid droplets and lysosomes in live and fixed cells. Such dual-organelle staining dyes monitor lipophagic processes.
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Recent innovative approaches for drug delivery systems targeting cancer and CNS disorders

J. Mater. Chem. B, 2026, 14,6132-6155
DOI: 10.1039/D6TB00411C, Review Article

Milind Kumar Anand, Elumalai Premalatha, Hariharan Moorthy, Thimmaiah Govindaraju
Advancements in drug delivery systems enable targeted, multifunctional, and stimuli-responsive therapies for cancer and neurodegenerative diseases, enhancing biological barrier penetration, therapeutic efficacy, and theranostic integration for clinical translation.
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Elaboration of antibacterial polyurethanes for medical devices by a scalable process

J. Mater. Chem. B, 2026, 14,6343-6354
DOI: 10.1039/D5TB02613J, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Baptiste Caron, Marc Maresca, Amélie Leroux, Marie Lemesle, Jean Louis Coussegal, Loic Fontaine, Elizabeth A. Murphy, Christopher M. Bates, Phong H. Nguyen, Phillip A. Kohl, Olivier Soppera, Stéphane Canaan, Isabelle Poncin, Yohann Guillaneuf, Catherine Lefay
Medical devices are critical for patient survival in hospitals, yet they represent a leading cause of infections.
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Substrate-directed zinc phosphate nanodeposition for durable dentin bonding: one-step interfacial dehydration and proteolysis resistance

J. Mater. Chem. B, 2026, 14,6270-6281
DOI: 10.1039/D6TB00339G, Paper

Yifan Chen, Yajie Cheng, Yadong Chen, Mengqi Pan, Yanji Lu, Xue Yang, Qi Zhong, Honghai Yan, Qiaojie Luo, Chang Shu, Wei Yao, Xiaodong Li
Substrate-directed in situ nano-ZnP deposition by demineralized dentin reduces interface-confined water to enhance hydrophobic monomer infiltration and inhibits proteolytic enzyme activity, thereby improving hybrid-layer durability.
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Coordination-driven self-assembled nanozyme-loaded GelMA microneedles for enhanced photodynamic therapy of diabetic infected wounds

J. Mater. Chem. B, 2026, 14,6221-6236
DOI: 10.1039/D6TB00649C, Paper

Lisha Jiang, Jiaqiao Liang, Tianyue Wu, Jianyang Shi, Chenggong Hu, Haibo Wang
Infected diabetic wounds, particularly those complicated by multidrug-resistant bacteria, pose a significant clinical challenge due to the limited efficacy of conventional debridement and antibiotic therapies.
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Bioinspired antimicrobial glass coatings for clear and infection-resistant surfaces

J. Mater. Chem. B, 2026, 14,6364-6376
DOI: 10.1039/D6TB00465B, Paper

Subhankar Maity, Arup Sarkar, Arindam Patra, Joy Mitra, Jayanta Haldar
Optically transparent glass surfaces that simultaneously prevent fogging, resist contamination, and eliminate microbial growth are highly desirable for medical optics, protective equipment, and advanced architectural applications.
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An entropy-driven DNA timer fluorescence sensor for one-pot sequential detection of three respiratory viruses

J. Mater. Chem. B, 2026, 14,6435-6444
DOI: 10.1039/D6TB00134C, Paper

Chiliang Lin, Shaoyun Peng, Junling He, Yong Tang, Haimin Zou, Chen Zhou
An entropy-driven DNA timer with an enzyme-degradable blocker enables multiplexed, time-programmed detection of respiratory viruses in a single reaction.
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Poly-L-lysine integration in PVA hydrogels enables stable, bioactive matrices for motor neuron differentiation and neural network formation

J. Mater. Chem. B, 2026, 14,6298-6310
DOI: 10.1039/D5TB02475G, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Shuqian Wan, Dorna Esrafilzadeh, Laura Poole-Warren, Kristopher Kilian, Ulises Aregueta Robles
Minimal PLL integration (0.002 wt%) in PVA hydrogels, via physical or covalent crosslinking, improved laminin retention, motor neuron progenitor adhesion and neurite growth without cytotoxicity or loss of hydrogel stability.
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Chitosan with defined intrinsic viscosity enables physicochemical entrapment of microplastics under in vitro gastric conditions

J. Mater. Chem. B, 2026, 14,6311-6322
DOI: 10.1039/D6TB00654J, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Claudio Casella, Santiago Ballaz, Rafael Luque, Umberto Cornelli
Investigating the influence of chitosan viscosity on the formation of protective hydrogels against gastric pH using integrated nanoparticle delivery systems.
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Eggshell-derived nanoparticles accelerate wound healing

J. Mater. Chem. B, 2026, 14,6323-6342
DOI: 10.1039/D6TB00239K, Paper

Proma Nagchowdhury, Swapnali Londhe, Sanchita Tripathy, Yogesh Chandra, Chitta Ranjan Patra
Overall scheme demonstrating the wound healing property of eggshell-derived nanoparticles.
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Freezing-induced ice–polymer structuring enables tough, additive-free hydrogels under extreme cold conditions

J. Mater. Chem. B, 2026, 14,6202-6220
DOI: 10.1039/D5TB02063H, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Jialun Wei, Dong Zhang, Yung Chang, Athena B. Santi, Amanda Gomez, Lijin Wang, Gabriela Romero Uribe, Jie Zheng
Ice crystals in physically crosslinked double-network hydrogels act as reinforcing, energy-dissipating domains, turning brittle ice into a load-bearing phase and giving frozen gels greater stretchability and fracture resistance than unfrozen gels.
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Microfluidic preparation of programmable porous conductive hydrogel microfibers for wide-range and sensitive physiological monitoring

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00641H, Paper

Ting-Yuan Hu, Shi-Yu Liu, Zhuang Liu, Xiao-Jie Ju, Rui Xie, Da-Wei Pan, Wei Wang, Liang-Yin Chu
Conductive hydrogel microfibers (CHMFs), renowned for their flexibility and knittability, have emerged as promising candidates for wearable strain sensors in health monitoring and human-machine interaction. To accurately capture diverse physiological...
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PCL-b-PLLA diblock copolymers with high performance to replace polyoxymethylene for tissue ligation clips

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00719H, Paper

Quan Zhao, Ziyun He, Lei Tang, Yang Pan, Shuhua Chang, Bin He, Nan Zhang
Current biodegradable polymers for absorbable tissue ligation clips are suffered from not possessing rigidity and toughness simultaneously compared with polyoxymethylene (POM) clips. To overcome the limitations, two series of biodegradable...
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Mechanistic insight into graphene coatings for oral biofilm inhibition and osteoblast compatibility

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00324A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Xin Chen, Jian Zhang, Shadi Rahimi, Katja Kozjek, Lena Larsson, Ivan Mijakovic, Santosh Pandit
The initial adhesion of bacterial cells to implant surfaces is a critical step in the development of biofilms, complex microbial communities that are highly resistant to conventional antimicrobial treatments. Once...
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Functional nanomaterials for homogeneous, wash-free biosensing

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00295A, Review Article

Sihan Liu, Wanwan Li
This review summarizes functional nanomaterials for homogeneous, wash-free biosensing, with emphasis on material and interfacial engineering for signal discrimination, assay performance, and practical applicability across major detection platforms.
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Crystallization of lipidated dexamethasone prodrugs: the linker matters

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00997B, Paper

Yanliang Dong, Lei Shen, Xiaoguang Shi, Xiangyue Deng, Weichao Shi, Shutao Guo
Linker chemistry governs the solid-state fate of lipidated dexamethasone prodrugs. A gem-dimethyl-constrained ketal linker promotes rigid, directional H-bond crystalline assembly, whereas the ester linker leads to amorphous aggregation.
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Electrospun PVA-chitosan nanofibers with antibacterial properties for wound healing: unveiling the potential of low molecular weight chitosan

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00497K, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Liqiong Li, Asier R. Muguruza, Francisco M. Arrabal-Campos, Tamara Férnandez, Silvia Fernández-García, Nuria Muñoz-Flores, Julia Lorenzo, Ignacio Fernández, Rafael Contreras-Caceres, Pablo Guardia
Low-MW chitosan/PVA electrospun nanofibers showed enhanced antimicrobial activity and promoted keratinocyte migration, demonstrating the importance of chitosan molecular weight in designing multifunctional wound-healing dressings.
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Elucidating molecular oxygen adsorption in ZIF-8 through integrated experimental and computational studies

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02395E, Paper

Chitrangda Singh, Priyam Mangal, Priyanka Surya, Sweta Singh, Sreedevi Upadhyayula, Rashi Mathur
Integrated experimental and computational studies for molecular oxygen adsorption, and diffusion behavior in biocompatible ZIF-8, as a proof-of-concept platform for localized oxygen supplementation.
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Effective gene editing of melanoma by delivery of Cas9 mRNA with highly branched poly(β-amino ester)

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02556G, Communication

Zhaowei Chu, Haiyang Yong, Zhili Li, Xi Wang, Bingjie Li, Cong Yan, Qinxiao Li, Yueran Tao, Dezhong Zhou, Songmei Geng
HPAE can effectively deliver Cas9 mRNA to enable gene editing of various melanoma cells.
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Ultrasonic nanoreactors: porous nanomaterials as multimodal platforms for precision ultrasound-responsive therapy and sonotherapy in nanomedicine

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00612D, Review Article

Zepu Chang, Jinpu Yang, Shuaidong Huo, Yu Zhou, Pengkun Zhao
This review highlights recent advances in porous nanomaterials as ultrasonic nanoreactors for ultrasound-responsive therapy and sonotherapy, covering their synthesis, mechanisms, and applications.
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Nitric oxide-enhanced blood–brain barrier penetration and mitochondria-targeted antioxidant carbon dots for Alzheimer's disease

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00133E, Paper

Xiaoting Han, Juanjuan Xue, Qi Zhang, Ruijie Li, Xing Guo, Qianqian Duan, Shengbo Sang
Therapeutic mechanisms of EMA-CDs by penetrating the BBB, inhibiting Aβ fibrillation, alleviating inflammation and clearing excessive ROS in AD.
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Hydrogel Photopolymerization within Microfluidic Droplets for Single Cell Encapsulation

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00258G, Review Article

Shiqi Lei, Xingdan Wang, Yan Liu, Yuheng Du, Zhihuan Li, Yajuan Guo, Renmeng Liu, Kaiwen Chen, Edward Ramsey, Kun Jiang, John Oakey, Zhongliang Jiang
Molecular investigation of specific gene expression patterns at single cell level could reveal the heterogeneity of bulk cell populations, facilitating the understanding of the interactive regulatory pathways that are hidden....
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Navigating early detection and image-guided therapy in pancreatic malignancies with multifunctional fluorescent probes

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00503A, Review Article

Jingyun Liu, Bin Guo, Lijun Jia, Zhenlong Wang, Fu Wang
The pancreas serves essential roles in both the digestive and endocrine systems, responsible for secreting digestive enzymes that facilitate nutrient breakdown in the small intestine and releasing hormones critical to glucose homeostasis.
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A hybrid membrane-miomimetic nanoplatform for synergistic photothermal/photodynamic therapy of hypoxic tumors

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00549G, Paper

Wei Chen, Jingchao Li, Haiyan Li, Yifang Liu, Xia Lu
A hybrid membrane-biomimetic nanoplatform is developed for synergistic photothermal/photodynamic therapy of hypoxic tumors.
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Polyethylene oxide-poloxamer 407 in situ forming gels: a dual-drug delivery system for periodontal application

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02868J, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Ali Raza, Piarina Reginold, Nataša Škalko-Basnet, Sybil Obuobi
In situ forming gel system composed of Poloxamer 407 with PEO as an additive to enhance mechanical properties of the system for delivery of hydrophilic and hydrophobic drugs to counter bacterial, inflammatory, and oxidative stress in periodontitis.
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MFO@BCZT- and metformin-integrated biomimetic hydrogel for magnetoelectric stimulation-induced neurogenesis and neuroprotection in synergistically promoting brain tissue repair

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00600K, Paper

Yuyan Wang, Jialu Li, Chengheng Wu, Polina Chernozem, Danila Koptsev, Enhao Zhang, Dmitry Wagner, Evgeny Yu. Gerasimov, Xiaoyin Liu, Gleb Sukhorukov, Maria Surmeneva, Roman Surmenev, Jie Ding, Dan Wei, Jing Sun, Roman Chernozem, Hongsong Fan
After injuries, the repair of brain tissue is hindered by poor neuronal regeneration and severe neuroinflammation. Although magnetoelectric (ME) stimulation has emerged as a promising wireless strategy to promote axonal...
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Correction: Injectable hydrogel-based localized delivery of IDO-galectin-3 mitigates neuroinflammation and promotes neuronal sparing after spinal cord contusion in rats

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB90064J, Correction

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Gopal Agarwal, Allison Campbell, Arun Wanchoo, Daniel Plant, Izabela Zmirska, Jacob Fuhr, Prodip Bose, Gregory A. Hudalla, Benjamin G. Keselowsky, Christine E. Schmidt
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Correction: Atomically dispersed copper(I) on tungstosilicic acid for catalytic protection against cisplatin-induced hearing loss

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB90063A, Correction

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Xiaochan Lu, Yin Chen, Yanmei Mo, Qingdong Zeng, Shaoqin Cen, Li Zeng, Hongyi Hu, Ao Li, Xia Gao, Bin Zhang
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Multifunctional pyrazino[2,3-g]quinoxaline derivative capable of acidochromic response, cancer cell imaging, and as an active layer for organic light-emitting diodes

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00439C, Paper

NEICHOIHOI LHOUVUM, Sosmitha Girisa, Anil Kumar, VINOD KUMAR Kumar VISHWAKARMA, Abhishek Rameshchandra Tiwari, Ajaikumar B Kunnumakkara, Jwo-Huei Jou, Achalkumar Ammathnadu Sudhakar
A nonplanar derivative of pyrazino[2,3-g]quinoxaline with eight flexible alkyl chains in the periphery, featuring donor-acceptor-donor non-planar architecture, was prepared, which exhibits a soft crystalline nature, a high molar extinction coefficient,...
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A GSH-scavenging and synthesis-blocking microneedle patch for augmenting photodynamic eradication of diabetic wound biofilm

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00905K, Paper

Haixia Zhang, Zhichao Ran, Yi Li, Jiaying Liu, Hangyu Wang, Junpei Mei, Peihang Song, Wenwei Liu, Chaoqun Liu, Kelei Guan, Ningning Song
Infected diabetic wound represents a significant clinical challenge, largely due to persistent bacterial biofilm infection that impede healing process. Photodynamic therapy (PDT), an emerging antibiofilm strategy, uses photosensitizers to yield...
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An Injectable Metal-Phenolic Network Hydrogel for Coordinated PRP Delivery in Osteoarthritis Treatment

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00140H, Paper

jing Shi, Tao Wang, mengyuan Dai, qinling Liu, Qingxin Fan, Lu Li, Sha Wan, Chen Fan, Yu Wang, Qingquan Kong
Osteoarthritis (OA) is a highly prevalent degenerative joint disease affecting over 500 million people globally, imposing substantial social and economic burdens. Current treatments, including platelet-rich plasma (PRP), are limited by...
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Bismuth hybrid halide with dual inhibition against α-amylase and acetylcholinesterase probed by structural, vibrational, and theoretical analysis

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02912K, Paper

Assala Bahloul, Mehdi Messaad, Sirine Smaoui, Bassem Khemakhem, Mohamed Abdelhedi
A Bi(III) hybrid halide shows effective dual inhibition of α-amylase and acetylcholinesterase, rationalized by combined crystallographic, vibrational, and theoretical analyses.
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Correction: Electrospun polymeric scaffolds enable 3D tissue-like functionality and efficient photoinduced contraction

J. Mater. Chem. B, 2026, 14,6120-6120
DOI: 10.1039/D6TB90055K, Correction

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Giulia Simoncini, Fabio Marangi, Ilaria Venturino, Vito Vurro, Andrea Bartolucci, Lorenzo Vannozzi, Ludovico Aloisio, Martina Rossi, Paola Moretti, Chiara Bertarelli, Giuseppe Maria Paternò, Guglielmo Lanzani
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Exosome-modified mesoporous polydopamine with saikosaponin D and ferric ions for immunotherapy of metastatic breast cancer

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00717A, Paper

Mengzhu Zhang, Yuzhu Hou, Botong Liu, Fei Yan, Rui Su
MFSE exerts a synergistic therapeutic effect on both primary and distant tumors via enhanced photothermal therapy and saikosaponin D.
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Carboxymethyl cellulose-collagen XVII composite hydrogel reprograms the immune-oxidative microenvironment for enhanced skin wound repair

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00143B, Paper

Xinlei Zhao, Haowen Zheng, Yuhang Liu, Yujia Xie, Xinyu Wang, He Song, Yu Shi, Zhenming Wang, Zhiai Hu, Ding Xiong, Ling Ye
CMC/COL17 hydrogel forms via electrostatic and hydrogen bonding as a topically applicable matrix. It reduces M1 macrophages and ROS, increases M2 macrophages, promotes fibroblast migration and accelerates re-epithelialization and collagen deposition.
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A near-infrared fluorescent-photoacoustic nanoprobe for tumor targeted photodynamic–photothermal therapy

J. Mater. Chem. B, 2026, 14,6065-6075
DOI: 10.1039/D6TB00206D, Paper

Di Zhao, Yingzhong Zhu, Shunyi Wang, Qiuqi Gao, Wanyang Li, Han Yang, Bo Wu, Lin Kong, Changjie Mao
NIR-light-excited PCB NPs simultaneously generate type-I ROS and achieve a PCE of 49.96%, enabling synergistic PDT/PTT tumor ablation with a TGI of 99.34%.
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Tyrosine monomer nanocrystal as a potent ice recrystallization inhibition activity

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00077K, Paper

Yong Duk Kim, Yedam Lee, Dong June Ahn, Dong-Kwon Lim
Nanoscale architecture alone does not guarantee effective ice recrystallization inhibition (IRI). The strong IRI activity of tyrosine monomer nanocrystals highlights the importance of chemical functionality, crystallinity, and colloidal stability.
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Ordered micro-nano structures: synergistic integration of microneedles and photonic crystals for advanced biomedical systems

J. Mater. Chem. B, 2026, 14,5859-5889
DOI: 10.1039/D6TB00254D, Review Article

Yihan Zhou, Tong Wu, Xin Li, Bingbing Gao
This review summarizes the fabrication challenges and hybrid application of ordered structures integrating microneedles and photonic crystals, which combine mechanical penetration with optical sensing to achieve synergistic biomedical functions.
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Embedding near-infrared fluorescent single-walled carbon nanotubes within freeform fabricated hydrogels via continuous digital light processing

J. Mater. Chem. B, 2026, 14,5960-5972
DOI: 10.1039/D6TB00108D, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Alexander Boltinhouse, S M Abu Naser Shovon, Saroj Subedi, Hussain Kawsar Chowdhury, Henry Oliver Tenadooah Ware, Januka Budhathoki-Uprety
Photoluminescent single-walled carbon nanotubes are embedded within free-standing scaffolds produced via continuous digital light processing technology.
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Impact of 2′-fluoro nucleobase modifications on CD detection, sensitivity and specificity of short oligonucleotides bound to alginate hydrogels

J. Mater. Chem. B, 2026, 14,6050-6064
DOI: 10.1039/D5TB02880A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Daisee K. Lubrin, Colin I. Elliott, Jean-Paul Desaulniers, Theresa Stotesbury
We discuss the synthesis, characterization, and analysis of label-free, short oligonucleotide-bound alginate hydrogels and improved function with 2′-fluoro nucleobase modification.
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An antibacterial gradient-pore artificial skin with high exudate-absorption and hemostatic properties

J. Mater. Chem. B, 2026, 14,5913-5923
DOI: 10.1039/D6TB00023A, Paper

Dongxiao Ren, Wenxi Zhu, Sai Yan, Shuang Wu, Xunda Feng, Ran Cao, Meifang Zhu
An antibacterial artificial skin with gradient-pore architecture is developed for chronic wound care. This asymmetric design enables rapid, unidirectional exudate transport to prevent backflow while promoting accelerated hemostasis and wound healing.
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Comparison of the optical characteristics of pseudo-resonance and non-pseudo-resonance structures

J. Mater. Chem. B, 2026, 14,5902-5912
DOI: 10.1039/D6TB00673F, Paper

Xinliang Guo, Wei He, Yufei Wang, Yuhang Wang, Wutong Du, Ryan Tsz Kin Kwok, Hongyan Liu, Ben Zhong Tang, Huajie Zhu
Five pairs of pseudo-resonance structures, which have two sets of physical data, such as two sets of NMR spectra in solution, and non-pseudo-resonance structures were synthesized under mild conditions.
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Natural antimicrobial polymeric coatings for contamination resistant wound dressings: biocompatibility and in vivo efficacy against MRSA

J. Mater. Chem. B, 2026, 14,5890-5901
DOI: 10.1039/D5TB02800K, Communication

Adjara Diarrassouba, Lea Magne, Cynthia Calligaro, Abdessalem Rekiki, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Jeremy Welsch, Annabelle Vigué, Markus J. Kettel, Michael Karl, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi
Natural bioactive wound dressings offer a promising strategy to prevent chronic wound infections and modulate inflammation in response to rising antimicrobial resistance.
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A baicalein nanoparticle-embedded mucoadhesive hydrogel for synergistic anti-inflammation therapy in ulcerative colitis

J. Mater. Chem. B, 2026, 14,6076-6088
DOI: 10.1039/D6TB00467A, Paper

Mengting Chen, Lu Han, Sai Li, Yuji Pu, Bin He, Qingqing Pan
A nanoparticle–hydrogel composite system was engineered to enhance the colonic delivery and oral bioavailability of baicalein, exhibiting synergistic anti-inflammatory effects with EGCG in a murine colitis model.
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A tumor cell membrane-engineered MXene nanoplatform for chemo–photothermal immunotherapy of bladder cancer

J. Mater. Chem. B, 2026, 14,6109-6119
DOI: 10.1039/D6TB00416D, Paper

Zijing Peng, Zhengnan Huang, Zhuofan Nan, Yilin Yan, Huaxing Li, Zeyi Wang, Wei Yao, Xiaodong Zhu, Bing Shen, Xiangqian Cao
Tumor cell membrane-coated MXene enables bladder tumor-targeted delivery of doxorubicin and photothermal heating under 808 nm irradiation, triggering synergistic chemo–photothermal–immunotherapy with enhanced CD8⁺ T-cell activation.
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A microglia membrane biomimetic platinum-based MOF-loaded quercetin nanodrug delivery system for the treatment of Alzheimer's disease

J. Mater. Chem. B, 2026, 14,6034-6049
DOI: 10.1039/D6TB00201C, Paper

Ruixin Zhao, Mengrong Guo, Fengmei Yang, Yujiao Yan, Die Tian, Liran Deng, Qi Wang, Meng Xie
Pt-MOF/Qu/BV2 can achieve multi-targeted treatment of Alzheimer's disease through synergistic antioxidant effects, chelation of metal ions, inhibition of Aβ, and restoration of microglial cell polarization.
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Ultrasound-assisted synthesis of a ZnO–Te/TeO2 nanocomposite for multidrug-resistant microorganism and biofilm eradication

J. Mater. Chem. B, 2026, 14,5924-5945
DOI: 10.1039/D6TB00128A, Paper

Huda Alqahtani, Shaimaa Magdy Abd El-Sattar, Nojoud Faqerah, Salwa Faisal, Moustafa A. Rizk, Shahira H. EL-Moslamy, Hani Nasser Abdelhamid, Islam Gomaa
ZnO-nanorod-decorated Te/α-TeO₂ nanosheet architecture with interfacial strain provides durable antimicrobial efficacy against multidrug-resistant bacteria and fungi, positioning it as a promising candidate for infection-resistant surface coatings.
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Bio-inspired metamaterial structured small-diameter vascular grafts for emulation of native arterial mechanics

J. Mater. Chem. B, 2026, 14,6020-6033
DOI: 10.1039/D6TB00178E, Paper

Xianhui Cai, Zhongfei Zou, Zhen Shen, Rui Guo, Xiong Yu, Xuanrong Zhu, Li Shen, Jiachun Li, Yuewei Chen
To solve the trade-off between mechanical strength and compliance in traditional small-diameter artificial blood vessels causing thrombosis and failure, inspired by collagen's corrugated structure, we designed a metamaterial composite tubular vessel.
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Unraveling site-specific dopant behavior governing antibacterial activity in doped titanate nanosheets

J. Mater. Chem. B, 2026, 14,5997-6007
DOI: 10.1039/D6TB00183A, Paper

Jooho Jung, Rika Hayashida, Minori Kawachi, Eri Yoshida, Osamu Nakagoe, Hideaki Sano, Shuji Tanabe, Kai Kamada
Antibacterial properties governed by dopant sites in Cu- and Ag-doped titanate nanosheets.
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Co-assembled ion-pair complex nanoparticles from tranexamic acid and metformin with enhanced transdermal efficacy against UVB-induced pigmentation

J. Mater. Chem. B, 2026, 14,5983-5996
DOI: 10.1039/D6TB00005C, Paper

Xinglong Zhang, Mengdie Ji, Mengjie Liu, Chen Xin, Yanzhi Yang, Junlong Qi, Qiaoxin Li, Hongda Zhu
Multifunctional nanoparticles (S-PMT) by co-assembling the ion-pairing complex of TXA and Met with p-EGCG enhance transdermal efficacy against UVB-induced pigmentation.
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Fluorescent self-reporting theranostic platforms for tumour therapy: from cytotoxin release monitoring to therapeutic feedback evaluation

J. Mater. Chem. B, 2026, 14,5836-5858
DOI: 10.1039/D6TB00272B, Review Article

Yuning Guan, Jilei Zhao, Shaobo Hou, Yingxin Sun, Yalun Yao, Zi Long, Jian-Liang Zhou, Chong Duan
Schematic representation of fluorescent self-reporting theranostic platforms (FSRTPs). Evaluating across single/dual-modal therapeutic strategies, focusing on the dual-parameter tracking of cytotoxin release and therapeutic feedback.
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Fabrication of functional polyethersulfone (PES)-based materials for blood purification

J. Mater. Chem. B, 2026, 14,5820-5835
DOI: 10.1039/D6TB00231E, Review Article

Haoyu Tang, Xinju Jiang, Jiemin Wang, Changsheng Zhao
This review summarizes PES-based materials for blood purification: perspectives, challenges, and guidelines from functionalization to biomedical applications.
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Graphene-based porous hydrogels with a tunable piezoresistive response for wearable strain sensing

J. Mater. Chem. B, 2026, 14,5973-5982
DOI: 10.1039/D5TB02688A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Nishadi M. Bandara, Khandaker Umaiya, Michael J. Joyce, Cesar E. Gouveia, Douglas H. Adamson
This study reports the synthesis of porous hydrogels templated by self-assembled, percolating graphene networks formed through the spontaneous exfoliation of graphite at oil–water interfaces.
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Near-infrared reinforced alginate-tyramine-curcumin gels for alleviation of osteoarthritis in an ACLT murine model

J. Mater. Chem. B, 2026, 14,6089-6108
DOI: 10.1039/D5TB00975H, Paper

Yao-Tung Tsai, Yu-Wen Tseng, Yan-Ting Chen, Shen-Han Wu, Hui-Wen Chiu, Hieu Trung Nguyen, Chueh-Hung Wu, Andrew E.-Y. Chuang, Wen-Shiang Chen, Chih-Kuang Chen
Osteoarthritis (OA) poses a significant challenge because of its complex pathology, involving factors such as hypoxia, inflammation, angiogenesis, oxidative stress within cell, and fibroblast-driven instability of fibrocartilage.
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Quercetin-functionalized gold/silver nanoparticles with tunable antibacterial selectivity for bacterial infection treatment

J. Mater. Chem. B, 2026, 14,5946-5959
DOI: 10.1039/D5TB02885J, Paper

Yuchen Xie, Liyun Ma, Yuxi Xiao, Xin Wang, Xu Yu, Ming Jiang, Li Xu
Quercetin-functionalized gold and silver nanoparticles with controllable antibacterial activity were prepared and applied for selective antibacterial therapy.
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Indole–bipyridyl fluorophores as dual-functional probes for endoplasmic reticulum imaging and Zn2+ sensing in live cells

J. Mater. Chem. B, 2026, 14,6008-6019
DOI: 10.1039/D5TB02797G, Paper

Mohini Ghorpade, Sayan Bera, Gayatri Bhattad, Paramasivam Mahalingam, Sriram Kanvah
Indole–bipyridyl fluorophores enable high-contrast imaging of the ER in living cells, showing excellent selectivity and sensitivity to stress-induced changes. They also act as Zn²⁺ sensors via coordination-induced fluorescence shifts.
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Donor-acceptor squaraine-based theranostic platforms for combined type I photodynamic, photothermal and chemo therapies

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00224B, Paper

Melek Pamuk Algi, Donay Cungur
Donor-acceptor-type squaraine dye is synthesized, and its phototherapeutic features are comprehensively evaluated for in vitro applications. It is noteworthy that squaraine shows both photodynamic and photothermal activity under illumination. More...
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Near-infrared-triggered synergistic therapy with Ru-based nanocomposite hydrogel for eradicating multidrug-resistant wound infections

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00808A, Paper

Zehui Xiao, Bingcong Ji, Jiangli Cao, Ting Du, Xinjun Du
The increasing prevalence of antimicrobial-resistant pathogens necessitates the development of innovative treatment strategies. To address this challenge, we designed a multifunctional hydrogel (RBP) by integrating berberine-loaded, polyethylenimine-modified mesoporous ruthenium nanoparticles...
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Combined improvement of osteogenic and anti-inflammatory activities of Sr-doped bone cement modified with carboxymethyl cellulose

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00609D, Paper

Xiao-Dan Li, Dawei Yan, Haohao Ren, Hai-Tao Peng, Kun Zhao, Qiyi Zhang, Yong-Gang Yan
Incorporating strontium into bone cement is an effective way for bone repair. Macrophages play an essential role during implant osseointegration. However, whether carboxymethyl cellulose (CMC) modifying Sr-doped bone cement can...
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Dynamic mechanical cues from hydrogels promote osteogenesis via the YAP signaling pathway

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00164E, Paper

Hai Liu, Lulong Zhao, Weilun Pan, Songlang Liu, Hongxing Liao, Jun Hu, Liqiong Liao
Guidance of photo-tunable dynamic stiffening hydrogel on the differentiation fate of BMSCs in vitro and application in calvarial defect regeneration in vivo.
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A vascularized modular 3D in vitro liver model to study bacterial infection and the role of associated host protein markers

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02750K, Paper

Manleen Kaur, Divyanjali Karki, Neetu Singh
A vascularized modular platform with regenerative signaling capabilities and host protein biomarker detection during bacterial infection.
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Development of a synthetic antimicrobial peptide targeting MDR wound pathogens and biofilms: effective therapeutics for chronic wound management

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00557H, Paper

Mayank Maan, Shubhi Joshi, Panchali Barman, Satvika Sharma, Avneet Saini
C-/N-terminal capping and D-amino acid enantiomerization improves peptide’s protease resistance, physiological stability, antimicrobial and antibiofilm activity, thereby enabling sustained infection control in chronic wound microenvironments.
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Engineering a dual-action nitric oxide and propolis releasing polymeric matrix for extended antimicrobial efficacy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00666C, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Aasma Sapkota, Sadah Schell, Mofoluwasade O. Popoola, Hitesh Handa, Elizabeth J. Brisbois
Fabrication of nitric oxide and propolis releasing polymeric matrix for application in infection-resistant medical devices.
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Inorganic Nanomaterials Empowering Bacteria: A New Paradigm for Biomedical Applications

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00687F, Review Article

Zhi Chen, Xiaolin Hou, Shuang Wang, Guobin Qi, Guanghui Ma, Wei Wei, Diwei Zheng
Bacterial therapy holds great potential in biomedicine, but its clinical application is hindered by challenges such as in vivo instability and biosafety concerns. Inorganic nanomaterials, with their excellent structural stability,...
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S. aromaticum aqueous extract derived carbon dots: A biosafe antibacterial nanocatalyst for water remediation

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00278A, Paper

Anurag Kumar Pandey, Sayan Mukherjee, Nantu Dogra, Sagar Pal, Tapan Kumar Nath, Santanu Dhara
The demands of non-toxic antibacterial nanocatalysts for water purification and wastewater treatment on the same platform open a greener approach for energy remediation applications. Carbon dots (CDs) derived from natural...
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Evaluation of Fe-MOF/graphene nanocomposites for non-enzymatic electrochemical sensing of acetaminophen

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02893K, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Jithin Rafi, Thangavelu Kokulnathan, Tzyy-Jiann Wang, Murugan Velmurugan, Bernaurdshaw Neppolian
The schematic representation of the fabrication of Fe-MOF/GR/GCE and its application towards the electrochemical sensing of APAP in different sample matrices.
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GalNAc-modified five-component lipid nanoparticles for liver-targeted delivery of p65 siRNA to alleviate cytokine storm in liver injury via NF-κB targeting

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00003G, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Zhijie Liang, Shaorong Li, Huali Huang, Shuying Luo, Hongmian Jiang, Lifeng Luo, Jinzhuai Li, Kun Zhao
GalNAc-modified five-component lipid nanoparticles enable liver-targeted delivery of p65 siRNA, effectively silencing NF-κB to alleviate cytokine storm and acute liver injury.
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Construction of two drug-loaded gold nanoclusters@mesoporous polydopamine nanospheres and their synergistic treatment of abdominal aortic aneurysms

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00744A, Paper

Wenhao Li, Weina Zhang, Qin Huang, Mengjie Xu, Dehong Wu, Qi Hu, Dianwu Wu, Guangfu Yin, Zhongbing Huang
To address therapy-need of abdominal aortic aneurysm (AAA), a targeting modified multifunctional nano delivery system (rCT AuM) was developed, including Au nanorod-cluster@mesoporous polydopamine core with c(RGDfK) targeting peptide and the...
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Synergistic silver nanoparticle-graphene quantum dot composites in silk fibroin/lathyrus protein-oxidized alginate hydrogels for accelerated diabetic wound healing

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00061D, Paper

Parth Gulati, Anuj Verma, Safoora Zaffar, Amiruddin Ali, Sanjay Kumar Gupta, Tatini Rakshit, Shubha Banerjee, Suchetan Pal
An injectable, self-healing oxidized alginate–protein hydrogel incorporating in situ formed AgNP–GQD composites enabled complete healing of infected diabetic wounds in rats within 8 days.
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Supramolecular peptide hydrogels for the treatment of ocular diseases: from tissue replacements to drug delivery systems

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00761A, Review Article

Daowei Xia, Wenting Li, Jing Xie, Dongdong Zhou, Hao Su
Supramolecular peptide hydrogels (SPHs), a unique class of dynamic three-dimensional networks formed by self-assembly of peptides, have demonstrated strong potential for ocular tissue replacement and drug delivery in ophthalmic application....
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Lactate-Sensitive Nanomachines for Enzyme-Controlled Drug Delivery in Cancer Therapy

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00119J, Paper

Marta González-Jiménez, Teresa Moreno, Beatriz Mayol, Esther García Díez, Soraya Salido, Alfredo Sánchez, Narcisa Martínez Quiles, Paloma Martínez-Ruiz, Diana Vilela, Reynaldo Villalonga
Here, we report the preparation of a novel enzyme-powered nanomachine for drug delivery system based on mesoporous silica nanoparticles capped with a cyclodextrin-lactate oxidase (CD-LOx) complex, which enables controlled cargo...
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Modifying Biological Heart Valve Leaflets using Anti-fouling Polymer Incorporated with Metal-Phenolic Networks for Enhanced Anti-Thrombosis, Anti-Calcification and Endothelialization

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00082G, Paper

Lepeng Chen, Kunpeng Liu, Hui Yan, Tiantian Zheng, Chen Li, Rifang Luo, Qinsheng Hu, Yunbing Wang
Promoting the endothelialization of the bioprosthetic valve is necessary to improve the performance of the valve, and good hemocompatibility ensures an adequate time for the endothelialization process. In this work,...
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Highly stable nanosized lucigenin@PS-COOH: a robust chemiluminescence system for sensitive cTnT analysis

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00753H, Paper

Fugang Li, Qiang Li, Feng Chen, Chenxu Yan, Yongxi Zhao, Zhiqian Guo
A novel lucigenin@PS-COOH nanoplatform is developed for cTnT detection, featuring exceptional stability and biocompatibility. This robust immunosensing system offers a high-performance pathway for the early diagnosis of cardiac events.
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A SiQD-based hydrogel fiber sensor for portable, on-site β-galactosidase detection in serum

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02562A, Paper

Dan Li, Yutao Shen, Zikai Xu, Wenfei Zhang, Na Li, Yong Zhao
A portable hydrogel fiber-optic sensor for on-site β-galactosidase (β-Gal) detection: β-Gal hydrolysis induces purple Cu(I)-BCA, which quenches SiQD fluorescence in hydrogel via an inner filter effect for point-of-care diagnostics.
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