RSC - J. Mater. Chem. B latest articles

Multifunctional polysulfone/strontium silicate composites with tunable properties through silane functionalization

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00741D, Paper

Yun-Ru Huang, Shinn-Jyh Ding
The development of osteogenic polymer-based bone implants is increasingly essential for load-bearing applications. Upcycling high-performance polysulfone (PSF) waste is a promising option for environmental sustainability. In this study, PSF derived...
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Precision biomaterial therapeutic strategies for osteolytic diseases

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00511J, Review Article

Hanyue Xue, Yangbin Wang, Keyu Kong, Sonu Ng, Yang Li, Wenxuan Fan, Zhe Wang, Qingpei Xue, Minghao Jin, Huiwu Li
Osteolytic diseases constitute a category of conditions characterised by persistent bone tissue destruction, commonly observed in pathological states such as osteomyelitis, periodontitis, metastatic bone cancer, and osteoporosis. Conventional therapeutic approaches...
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A Template-Defined TA–Fe Nanoplatform Enables Mechanistic Decoupling and Lysosome-Gated Immunomodulation for Diabetic Wound Healing

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00653A, Paper

Shahid Mahmood, Zhichao Feng, Lin Shu, Nan Li, Xinyi Meng, Jiazhi Duan, Chunhui Sun, Chao Liu, Hong Liu, Congcong Zhang
Complex injury microenvironments often render conventional extracellular delivery a “black box”, where efficacy is constrained by the efficiency–off-target trade-off, signal distortion by inflammation/ROS, and limited causal attribution of mechanism. Here,...
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Self-powered thermoelectric gel dressings for chronic wound monitoring and therapy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00979D, Review Article

Jie Zhang, Chunjing Wang, Suyi Wen, Kunjiao Liu, Haonan Yue, Shaojie Liu, Xiaojing Cui, Shengli Cao, Hulin Zhang
This review covers thermoelectric gel dressings’ mechanisms, materials, self-powered multimodal monitoring (temperature, pressure, biomarkers), electrical stimulation for healing, and applications in diabetic feet and infected wounds.
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“Dual-Lock”-Controlled activatable nanotheranostics for chemiluminescence resonance energy transfer (CRET)-driven enhanced photoimmunotherapy

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00913A, Paper

Xuxuan Gu, Liwen Sun, Huangchengzhi Zhang, Gaoyuan Liu, Yaxin Cui, Wen Zhou, Qi Wang, Chen Xie, Quli Fan
Photoimmunotherapy is a promising therapeutic modality which utilizes phototherapy to trigger immune responses for cancer therapy. However, the requirement of light to trigger the therapeutic procedure greatly suppress its efficacy...
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Tanshinone IIA nano-liposomes ameliorate cerebral ischemia-reperfusion injury associated with activation of the PGK1/Nrf2 signalling axis

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB01076H, Paper

Zhijie Ou, Xiaofeng Dong, Yan Wu, Yuanqi Wang, Jiaping Xu, Meiling Sun, Delian Kong, Guodong Xiao, Juping Chen, Chunfeng Liu
Ischemic stroke poses a major global health challenge, characterized by high rates of disability and mortality.
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Functional group effects on mephedrone adsorption in UiO-66-type metal–organic frameworks

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00429F, Paper

Grzegorz Kurowski, Kornelia Hyjek, Klaudia Dymek, Witold Piskorz, Anna Pajdak, Anna Boguszewska-Czubara, Barbara Budzyńska, Justyna Grymuza, Weronika Mrozek, Łukasz Kuterasiński, Magdalena Szumera, Przemysław J. Jodłowski
Systematic functionalization of UiO-66 reveals molecular mechanisms governing selective adsorption and toxicity mitigation of psychoactive contaminants in biologically relevant media.
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An ultrasound-responsive lipoic acid-based bioadhesive for oral mucosal wound repair

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02927A, Paper

Yige Wei, Bao Xia, Ming Gong, Hengjie Zhang, Kunrei Liu, Zhipeng Gu, Huixu Xie
An ultrasound-responsive lipoic acid-based hydrogel enables in situ gelation, wet adhesion, and oral mucosal wound repair.
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Molecularly designed star-shaped PLA-based polymers with enhanced piezoelectricity for ultrasound-driven wound healing

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00652C, Paper

Guyue Liu, Jing Ma, Wei Liu, Jingzhou Fang, Qianhe Sun, Meng Cui, Xue Li, Xiuqin Zhang
Star-shaped PLA-based polymers were synthesized, which showed the highest piezoelectricity due to α-crystals and high crystallinity, enabling ultrasound-activated wound healing.
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A low-cost titanium suboxide pH sensor with competitive operational lifetime assessed with electrochemical impedance spectroscopy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02697K, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Kyriakos Almpanidis, Apostolos Panagiotopoulos, George Kakavelakis, Leslie Askew, Xiaoqian Pu, Dimitar I. Kutsarov, Steven J. Hinder, S. Ravi P. Silva, Vlad Stolojan
The TiO_x/Ag pH sensor demonstrates an operational lifetime comparable to state-of-the-art devices, while relying on cost-effective material components.
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Melanocortin 1 Receptor-Targeted Peptide-Functionalized Liposomes for Enhanced Melanocyte-preferential Drug Delivery and Anti-Melanogenic Efficacy

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00172F, Paper

Donghan Kim, Hwira Baek, Marta Gonçalves, Seyoung Yang, Seungjae Lee, Kyeongdeok Jang, Yun H Hwang, Jae Sung Hwang, Youngbok Lee, Jin Woong Kim
Melanocyte-preferential drug delivery remains challenging due to limited targeting strategies for pigmentary disorders. Here, melanocortin 1 receptor (MC1R)-targeted liposomes (MELA-Lipos) functionalized with melanotropic peptides are developed for melanocyte-directed delivery. Peptide-lipid...
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Teratoma Development from Subcutaneously Transplanted Embryonic Stem Cells in Prevascularized Graft Beds

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB01136E, Paper

Huaxin Yang, Yuyue Zhang, Xiaoxi Shen, Tingting Tang, Chaochang Li, Hao Wang, Zijiang Yang, Chenjie Xu
Subcutaneous implantation is favored for its accessibility and safety, making it a valuable site for cell transplantation. However, the relatively poor vascularization of the subcutaneous space hinders the implant's integration...
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The development of multifunctional polysuccinimide with programmable thermoresponsiveness by modulating the hydrophobic graft architecture for advanced drug delivery applications

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00805D, Paper

Eunhye Yun, Chaenyung Cha
This study developed a new class of thermoresponsive hydrogels based on multifunctional polysuccinimide capable of providing tunable thermoresponsive properties for drug delivery applications.
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Functional Nanoprobes for Early Diagnosis and Precision Theranostics of Parkinson's Disease: A Review of Material Strategies and Multimodal Sensing

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00813E, Review Article

Mingtang Zeng, Tao Chen, Yao Wang, Chenji Hu, Xi Yin, Chao Shen, Xueyan Wang
The pressing need for early and accurate diagnosis of Parkinson's disease (PD) has motivated the development of advanced nanoscale diagnostic tools. Functional nanoprobes, owing to their tunable physicochemical properties and...
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Exploring the influence of internal surface modification of paramagnetic mesoporous silica nanoparticles on MRI relaxation dynamics

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB01037G, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Connor J. R. Wells, Marwa M. I. Rizk, Joseph R. H. Manning, Danielle Winning, Carlos Brambila, Dermot F. Brougham, Fabio Carniato, Mauro Botta, James D. E. T. Wilton-Ely, Gemma-Louise Davies
Internal surface functionalisation of mesoporous silica nanoparticles tunes the local environment surrounding immobilised Gd³⁺ chelates. Thiol and phenyl groups enhance MRI relaxivity through distinct effects on local rotational dynamics.
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Dissolving microneedles loaded with chitosan oligosaccharides and gallic acid-modified ε-poly-L-lysine for the combined antibacterial and anti-inflammatory therapy of acne vulgaris

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00953K, Paper

Yan Du, Miao Zhang, Hongyan Jiang, Genmeng Yang, Ruike Xu, Ziqing Lin, Zhuo Wang, Yurong Sun, Hongqiang Gao, Kuangpin Liu, Hailei Wang
A dissolving microneedle (CEGP MNs) patch was fabricated using chitosan oligosaccharide (COS), gallic acid-modified ε-poly-L-lysine (EPL–GA) and polyvinyl alcohol (PVA) for acne therapy.
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A ROS-responsive supramolecular peptide hydrogel attenuates rheumatoid arthritis by modulating synoviocyte activity and inflammatory microenvironments

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00825A, Paper

Haipeng Wang, Liyuan Peng, Chenyang Wang, Shaohua Liang, Jiaxin Zhou, Kunyu Wang, Xiaoyu Zhang, Gongyu Li, Zhen Zheng
Rheumatoid arthritis (RA) is sustained by a pathogenic circuit involving oxidative stress, synovial inflammation, and fibroblast-like synoviocyte (FLS) hyperactivation.
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Physicochemical stability and protein corona profiling on the interaction of iron oxide nanoparticles with human tears

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02620B, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Bhagyasree Paila, Sneha Asok, Anil K. Suresh
The integration of nanotechnology into ophthalmology represents a promising frontier for the development of precision diagnostics and therapeutics aimed at enhancing ocular health.
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Polyphenol-based nanoparticles enhancing doxycycline efficacy for acne therapy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02875B, Paper

Lian Wang, Junmei Song, Hao Wang, Tianyou Wang, Jiaqi Li, Ningrui Cao, Yiwen Li, Zhipeng Gu, Xian Jiang
This work presents an EGCG–doxycycline co-assembled nanoplatform for acne therapy. By targeting skin microenvironment, it aligns material design with acne pathology and enhances topical treatment efficacy for inflammatory skin disorders.
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A 3D-bioprinted hydrogel platform with tunable matrix stiffness reveals mechanical adaptation and doxorubicin resistance in triple-negative breast cancer

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00892E, Paper

Sriram Bharath Gugulothu, Joel P. Joseph, Kaushik Chatterjee
Triple-negative breast cancer progression and the therapeutic response are strongly influenced by the properties of the 3D-bioprinted matrix.
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From neural stem cells to cell-free exosome nanotherapy: reprogramming the injured spinal cord microenvironment for regeneration

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB01356B, Review Article

Cheng Zhang, Xiao-Yin Liu, Bolin Zhao, Jia Luo, Wenhui Liu, Yun Hao, Fuheng Hu, Siyi Li, Liyuan Jin, Wei Huang, Xiaohui Yu, Liangxue Zhou, Jianguo Xu, Jiaojiang He
Spinal cord injury (SCI) is a severely disabling neurological disorder with a global prevalence of approximately 10.5 cases per 100,000 individuals. The pathophysiological mechanisms underlying SCI encompass both primary mechanical...
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A Multi-Target Nano-Therapy Against Cerebral Ischemia/Reperfusion Injury via Synergistic Inhibition of Neuroinflammation and Pyroptosis

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00794E, Paper

Wenchao Fu, Ayang Zhao, Bo Chen, Yu Feng, Hongliang Shen, Jietao Li, Xianzhang Zeng
Background & Purpose: Ischemic stroke reperfusion injury involves a vicious cycle of neuroinflammation, pyroptosis, and oxidative stress. Single-target therapies have limited efficacy. This study aimed to develop an actively targeted,...
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Hydrogels as an emerging engineering platform for immobilizing cells or enzymes

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00860G, Review Article

Zhiqiang Sun, Yitong Wang, Cheng Cai, Jun Xie
Hydrogel platforms for cell/enzyme immobilization: rational design, structure–activity relationships, and applications.
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Stellera chamaejasme‑derived multifunctional biocomposite with antibacterial, mosquito‑repellent, and biodegradable properties

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB01195K, Review Article

Shiyu Wang, Ruiyang Yang, Wen Wen, Lunqiang Jin, Ciren Wangjie, Drolma Dawa, Lin Tan
The increasing threat of healthcare-associated infections and mosquito-borne diseases demands new materials that combine antimicrobial protection, insect repellency, and biocompatibility. Here, we convert Stellera chamaejasme L. (SC), an ecologically harmful...
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Natural ginger extract promotes wound healing via antioxidant and anti-inflammatory

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00938G, Paper

Conglai Zhou, Xiaojun Ai, Xiaoli You, Guoxu Chen, zhaoming liu, Li Tian
Wound repair has always been a hot topic in medical research, but at present, many studies focus on expensive synthetic chemical materials, and little attention is paid to green and...
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Precise Microfluidic Engineering of mRNA Lipid Nanoparticle-Loaded polycaprolactone Microcapsules for Sustained Delivery

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00833J, Paper

Hao Bai, Baiqiu Chen, Ziyue Wang, Hongquan Wang, Zhenghao Hu, Yiqing Chen, Chengfan Wu, Qi Shuai, Yunfeng Yan
mRNA therapy holds promise for treating a variety of diseases, but its clinical application faces significant challenges, including rapid degradation in vivo and the need for frequent injections. Lipid nanoparticles...
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MOF-based tri electrode aptasensor platform for effective detection of sepsis markers with minimal cross-interference

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00732E, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Shubhangi Shukla, Siba Sundar Sahoo, Sachin Kadian, Meagan Morgan, Roger J. Narayan
In this study, we report a trimodal polymethyl methacrylate (PMMA)-based multiplex electrochemical aptasensing platform for the concurrent detection of procalcitonin (PCT), C-reactive protein (CRP), and interleukin-6 (IL-6) levels.
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Diradical-featured N-arene croconaine-based nanoagent for synergistic photodynamic/photothermal tumor therapy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB01182A, Paper

Yiru Tang, Xiaoyu Zhu, Yating Zeng, Wanying Li, Na Hao, Ji Lu, Bowen Lei, Yao Jian, Lin Yang
The diradical-featured N-arene croconaine CR620 nanoparticles enable synergistic photodynamic/photothermal therapy, achieving 89% tumor growth inhibition in 4T1 mouse models, establishing a stable and promising bifunctional platform.
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Photodynamically active AIE-functionalised casein nanofibers for antibacterial wound management in epidermolysis bullosa

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00802J, Paper

Nikolay Estiven Gomez Mesa, Resmarani Sahu, Quan Trong Luu, Krasimir Vasilev, Youhong Tang
A biocompatible photodynamic dressing integrating natural polymers and an aggregation-induced emission photosensitiser, providing a promising approach for infection control and wound management in fragile skin conditions such as epidermolysis bullosa.
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Positively Charged, Phenolic Hydroxyl and Anthraquinone Structured Polystyrene Microspheres Targeting Dual Elimination of Bacterial Pathogens and Pathogen-Associated Molecular Patterns for Sepsis Therapy

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00999A, Paper

Chunji Jiang, Jianxu Bao, Ziyue Ling, Yupei Li, Changsheng Zhao, Weifeng Zhao
During bacterial infection in sepsis, both the bacteria and pathogen-associated molecular patterns (PAMPs, including endotoxins and exotoxins) contribute to the progression of sepsis. Traditional single-target bactericidal therapies commonly prove ineffective...
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Correction: Nanosheet-pore topographical titanium substrates: a biophysical regulator of the fate of mesenchymal stem cells

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB90086K, Correction

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Kui Xu, Xinkun Shen, Weizhen Chen, Caiyun Mu, Chao Jiang, Yongchun Zhao, Kaiyong Cai
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Correction: Influence of strontium ions incorporated into nanosheet-pore topographical titanium substrates on osteogenic differentiation of mesenchymal stem cells in vitro and on osseointegration in vivo

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB90087A, Correction

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Kui Xu, Weizhen Chen, Yan Hu, Xinkun Shen, Gaoqiang Xu, Qichun Ran, Yonglin Yu, Caiyun Mu, Kaiyong Cai
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Carbon dot-decorated Ni-MOF heterojunction sonozymes for enhanced sonodynamic-chemodynamic cancer therapy

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00956E, Paper

Qitao Huang, Han Li, Xiqian Cao, Yan Zhao, Bijiang Geng, Jia Liu
In recent years, sonodynamic/chemodynamic therapy (SDT/CDT) has emerged as a promising ROSdependent antitumor strategy owing to its noninvasiveness, suitability for deep-seated tumors, and favorable tumor selectivity. However, current sonosensitizer nanoplatforms...
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Computational and experimental study of solution-based assemblies of bottlebrush diblock copolymers

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00815A, Paper

Chiraz Toujani, Zachary Cartwright, Jeonghun Lee, Margarita Herrera-Alonso, Abelardo Ramírez-Hernández
Amphiphilic bottlebrush block copolymers are promising materials due to their ability to self-assemble into complex structures with potential applications in biomedical and electronic fields.
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HRP-crosslinked silk–gelatin bioinks: printability dynamics and modulation of stem cell lineage commitment in 3D bioprinted constructs

J. Mater. Chem. B, 2026, 14,7476-7498
DOI: 10.1039/D6TB00628K, Communication

Chandrashish Roy, Priya Banerjee, Sourabh Ghosh
Advancements in 3D bioprinting demand bioinks that demonstrate not only precise printability and mechanical robustness but also consistent biochemical and cellular performance.
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Tumor-targeting semi-rigid metal–organic–polymer framework nanoparticles with high adaptability and bioavailability

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00472E, Paper

Shuxuan Liu, Kaiteng Pang, Meili Sun, Jie Qiao, Hongjing He, Yao Wang, Liqiong Liao, Hao Li, Guofu Zhou
We developed novel Cu-based metal-organic-polymer framework nanoparticles using 1,3,5-trimesic acid and poly(acrylamide-co-acrylonitrile). Their thermal response, biodegradability, and Fenton-like catalysis enhance targeted drug delivery.
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Coordination-driven self-assembly of antioxidative and anti-inflammatory cerium–luteolin nanoparticles for effective treatment of ocular alkali burns

J. Mater. Chem. B, 2026, 14,7719-7735
DOI: 10.1039/D6TB00573J, Paper

Chuannan Chen, Jie Yu, Dongni Yao, Yangqi Zhao, Qiao Jin, Yao Liang, Yue Zhao, Yi Dong, Mengyue Xu, Peijin Qiu, Liqun Jin, Chaoyang Hong, Ting Shen
Ocular alkali burns are a severe ophthalmic emergency characterized by excessive production of reactive oxygen species (ROS), persistent inflammation, and corneal neovascularization, often resulting in visual impairment.
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ApoEVs@FeSe2–RGD as a synergistic redox–immune regulator for accelerating wound healing

J. Mater. Chem. B, 2026, 14,7688-7705
DOI: 10.1039/D6TB00418K, Paper

Zhen Ma, Minghao Zhou, Juan Tong, Bin Zhu, Jin Liu, Hongbo Wei, Kun Xuan, Xinyu Qiu, Jiang Wang
A schematic illustration of the fabrication and therapeutic mechanism of ApoEVs@FeSe₂–RGD for accelerating wound healing.
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A shikonin-based self-assembled nanomedicine alleviates DSS-induced colitis involving HDC-associated histamine regulation and gut microbiota modulation

J. Mater. Chem. B, 2026, 14,7659-7675
DOI: 10.1039/D6TB00517A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Wang Zhang, Jingrou Sun, Ying Ou, Jing Zhang, Yilan Bai, Jingxi Hong, Lingchang Meng, Yi Song, Tiepeng Wang, Zhiting Sun, Jing Wu
Zn-SHK-PEG NPs in DSS-induced colitis. (A) Synthesis of Zn-SHK-PEG NPs. (B) Zn-SHK-PEG NPs suppressed inflammatory cell infiltration, repaired gut barrier, and regulated gut microbiota. (C) Macrophage inflammation via PKM2-associated HDC regulation.
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From materials to medicine: formulation-driven optimization and clinical prospects of NIR-II optical imaging agents

J. Mater. Chem. B, 2026, 14,7412-7434
DOI: 10.1039/D6TB00661B, Review Article

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Junjie Zou, Lijuan Yang, Wenxiang Zhang, Gang Liu, Zhixiang Lu
Schematic diagram of NIR-II fluorescent classification. Combination image of clinical medical application, NIR-II imaging system and multimodal imaging.
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Wearable electrochemical biosensors for sweat uric acid detection: next generation technology for personalised healthcare

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00401F, Review Article

Pushpesh Ranjan, Ravi Prakash Verma, Biswajit Saha
A wearable electrochemical biosensor for real-time monitoring of uric acid in sweat. Its integration with wireless and AI technologies enables real-time data management, fostering personalised healthcare to address potential risks associated with UA.
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An intelligent responsive nanoplatform based on a DNA nanoflowers/Mn:CuS hybrid for targeted and synergistic cancer therapy

J. Mater. Chem. B, 2026, 14,7604-7614
DOI: 10.1039/D5TB02930A, Paper

Mengqin Zhang, Yang Wu, Ling Hu, Dongni Pei, Jianxiu Wang, Xinyao Yi
A schematic illustration of the design and assembly of DOX@Mn:CuS@DNA-NFs for targeted and synergistic cancer therapy.
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Genetically engineered outer membrane vesicles as next-generation bionanomaterials for therapeutic and diagnostic applications

J. Mater. Chem. B, 2026, 14,7400-7411
DOI: 10.1039/D6TB00650G, Review Article

Xuyu Bian, Ziyan Huang, Chenhang Xu, Jiawei Yue, Yumin Wu
Genetic engineering reprograms bacterial outer membrane vesicles (OMVs) into modular bionanoplatforms. Surface, cargo, and membrane engineering empower these engineered OMVs for cancer immunotherapy, vaccines, targeted delivery, and diagnostics.
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Engineered carbon-based quantum dots: a next-generation nanomedicine for the therapy and diagnosis of infectious diseases

J. Mater. Chem. B, 2026, 14,7435-7475
DOI: 10.1039/D5TB02755A, Review Article

Kallol Roy, Esha Roy, Nibedita Saikia, Pankaj Barman, Binoy K. Saikia, Rituraj Konwar
This review comprehensively discusses the recent progress on native CQDs and GQDs, with their EQDs for the therapy and diagnosis of infectious pathogens, along with the potential challenges and future directions for clinical translation.
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Hemoglobin-based oxygen carriers with antioxidant properties

J. Mater. Chem. B, 2026, 14,7528-7542
DOI: 10.1039/D5TB02538A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Tanmay Salvi, Asim Khan, Peyton Dickerson, Griffin J. Beyer, Andre F. Palmer
Polydopamine coating imparts antioxidant properties to artificial oxygen carriers, T- and R-state PolyHb, for the dual function of oxygen delivery and combating reactive oxygen species.
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Versatile Janus dressing with radiative cooling and exudate control for outdoor wound management

J. Mater. Chem. B, 2026, 14,7676-7687
DOI: 10.1039/D6TB00872K, Paper

Jianhua Zhu, Fengkai Zhou, Ruiyun Zhang, Yinan Fan, Liu Liu, Qian Zhang, Jianyong Yu
A Janus dressing integrating radiative cooling, unidirectional fluid transport, and photocatalytic antibacterial activity, fabricated via sequential electrospinning for sun-exposed wound healing.
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Localised Al(OH)3 quantum dot passivation for safe-by-design rutile TiO2 nanomaterials for UV protection

J. Mater. Chem. B, 2026, 14,7558-7576
DOI: 10.1039/D6TB00995F, Paper

Nuwangi P Cooray, Rajib Chandra Das, Philip J. Barker, Michael LF Lerch, Konstantin Konstantinov
Titanium dioxide (TiO₂) is a cornerstone UV-filtering material, yet its intrinsic photocatalytic activity continues to raise concerns regarding safety and photostability in cosmetic applications.
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A stimuli-responsive gradient-structured membrane for dual controlled release of bioactive agents: application to chronic wound dressings

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02922H, Paper

D’orgevale Chobli, Katia María Pérez Andeliz, Sébastien Massier, Louise Hespel, Stéphane Marais, Anthony C. Duncan
The elaboration of a double compartment membrane made of an asymmetric PBSA membrane containing electrospun PVA fibers allow a dual controlled release of bioactive agents.
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Unimolecular micelles as an effective carrier of poorly water-soluble nifuratel for selective in vivo anticervical cancer therapy via mucoadhesive dynamic hydrogels

J. Mater. Chem. B, 2026, 14,7543-7557
DOI: 10.1039/D6TB00746E, Paper

Monika Gosecka, Mateusz Gosecki, Malgorzata Urbaniak, Ewelina Wielgus, Renata Gruszka, Monika Marcinkowska, Barbara Klajnert-Maculewicz, Anna Janaszewska
Non-linear amphiphilic copolyether dynamic hydrogels as safe and effective nifuratel carriers for localized cervical cancer monotherapy: an in vivo study.
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PCL-b-PLLA diblock copolymers with high performance to replace polyoxymethylene for tissue ligation clips

J. Mater. Chem. B, 2026, 14,7706-7718
DOI: 10.1039/D6TB00719H, Paper

Quan Zhao, Ziyun He, Lei Tang, Yang Pan, Shuhua Chang, Nan Zhang, Bin He
A PCL-b-PLLA block copolymer clip for tissue ligation delivers a closure force comparable to POM (27.9 N vs. 29.0 N), while exhibiting a controlled, slow degradation profile that ensures structural integrity during the healing period.
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An MFO@BCZT- and metformin-integrated biomimetic hydrogel for magnetoelectric stimulation-induced neurogenesis and neuroprotection, synergistically promoting brain tissue repair

J. Mater. Chem. B, 2026, 14,7630-7646
DOI: 10.1039/D6TB00600K, Paper

Yuyan Wang, Jialu Li, Chengheng Wu, Polina Chernozem, Danila Koptsev, Enhao Zhang, Dmitry Wagner, Evgeny Gerasimov, Xiaoyin Liu, Gleb Sukhorukov, Maria Surmeneva, Roman Surmenev, Jie Ding, Dan Wei, Jing Sun, Roman Chernozem, Hongsong Fan
A biomimetic hydrogel integrating metformin and magnetoelectric MFO@BCZT nanoparticles provides neuroprotection and wireless electrical stimulation, synergistically promoting brain tissue repair after traumatic brain injury.
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Donor–acceptor squaraine-based theranostic platforms for combined type I photodynamic, photothermal and chemo therapies

J. Mater. Chem. B, 2026, 14,7593-7603
DOI: 10.1039/D6TB00224B, Paper

Melek Pamuk Algi, Donay Cungur
Theranostic platforms based on a new donor–acceptor type squaraine for type I photodynamic, photothermal and chemo therapies are disclosed.
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Modifying biological heart valve leaflets using anti-fouling polymers incorporated with metal–phenolic networks for enhanced anti-thrombosis, anti-calcification and endothelialization

J. Mater. Chem. B, 2026, 14,7647-7658
DOI: 10.1039/D6TB00082G, Paper

Lepeng Chen, Kunpeng Liu, Hui Yan, Tiantian Zheng, Chen Li, Qinsheng Hu, Rifang Luo, Yunbing Wang
Promoting endothelialization of the bioprosthetic valve is necessary to improve the performance of the valve, and good hemocompatibility ensures adequate time for the endothelialization process.
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Hepatocyte purification column using thermoresponsive glycopolymer-modified silica beads

J. Mater. Chem. B, 2026, 14,7499-7511
DOI: 10.1039/D6TB00422A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Kenichi Nagase, Junnosuke Matsuda
Thermoresponsive glycopolymer brush modified beads were fabricated via silane coupling reaction and subsequent tandem ATRP. The column packed with these beads can facilitate hepatocyte separation with the help of temperature modulation.
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Synergistic polyphosphate–gallic acid system heals infected skin defects by remodeling the immune microenvironment and restoring bioenergetics

J. Mater. Chem. B, 2026, 14,7512-7527
DOI: 10.1039/D6TB00614K, Paper

Rui Xu, Wang Sun, Longxiang Yao, Hua Zeng, Xinyu Qu, Jiaqi Fang, Ziheng Bu, Ximan Yang, Xiaoya Jin, Mengting Yin, Feng Chen, Bing-Qiang Lu
Infected skin defects persist in a pathological state characterized by dysregulation of the immune microenvironment and impaired bioenergetics, requiring coordinated treatment strategies to remold them.
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One probe, two chemistries: an orthogonal fluorescent sensing platform for glutathione and hydrazine in biological fluids and food samples

J. Mater. Chem. B, 2026, 14,7615-7629
DOI: 10.1039/D5TB02823J, Paper

Suraj Pise, Nilanjan Dey
Simultaneous detection of glutathione (GSH) and hydrazine (N₂H₄) is crucial due to their opposing roles in redox biology, GSH as a key intracellular antioxidant and hydrazine as a toxic nucleophilic pollutant and enzymatic byproduct.
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Morphological and compositional basis of silk fiber function in Actias luna

J. Mater. Chem. B, 2026, 14,7577-7592
DOI: 10.1039/D5TB01008J, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Lauren E. Eccles, Bert Foquet, Amanda Markee, Rebecca K. Liwang, Kari B. Basso, Akito Y. Kawahara, Whitney L. Stoppel
Silk is a highly versatile natural protein fiber with a wide range of uses, yet its diversity in composition and function remains poorly understood across the tree-of-life.
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COF-mediated tumor microenvironment-responsive platform and prodrug activation for combined chemo-sonodynamic cancer therapy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00743K, Paper

Tingyan Jiang, Wenjing Wei, Junhe Ou, Luwen Zhang, Jiarui Qiao, Maolin Pang
The prodrug was released and activated by glutathione (GSH). Reactive oxygen species (ROS) were generated for the COF mediated platform, and excellent antitumor efficacy was achieved by combined chemo-sonodynamic therapy.
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Bioactive powder adhesive featuring clotting synergy for alveolar extraction socket hemostasis and regeneration

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB01082B, Paper

Mingpu Sun, Danyang Wang, Chuanchuan Fan, Chunyan Cui, Qihui Zhou, Wenguang Liu
A hemostatic-to-regenerative cascade: polylipoic acid-sodium lipoate/quaternized chitosan powder evolves into a bioactive hydrogel, concentrates clotting components, and enables visceral sealing, dry socket prevention, and sutureless vascular repair.
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Tyrosine-capped gold nanoparticles enable cysteine-free peptide loading, enhancing the antipseudomonal efficacy of scorpion-derived AamAP1-Lys-NH2 in a burn wound infection model

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00168H, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Rosalind J. Van Wyk, Mandelie van der Walt, June C. Serem, A. James Mason, Megan J. Bester, Anabella R. M. Gaspar
Tyrosine-capped AuNPs enable near-complete loading of AamAP1-Lys-NH₂, reduce cytotoxicity and protease degradation and preserve antimicrobial activity. Nanoparticles improve survival in P. aeruginosa burn wound infections, supporting wound therapy.
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Vortex-enhanced bone regeneration: gyroid gradient scaffolds tune permeability for hemodynamic-accelerated osseointegration

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00772D, Paper

Yun Zhao, Zuohua Ren, Lichi Guo, Ruochen Duan, Mingyi Li, Dongni Liu, Shengwei Zhang
Vortex-enhanced gyroid gradient scaffold designed via simulation and SLM printing shows 21% higher permeability and 35% greater new bone area in vivo, confirming accelerated osseointegration via enhanced transport.
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Research progress of plant protein-based electrospun nanofibers as wound dressings

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00768F, Review Article

XingZhi Wang, Lu Jiang, YunRui Li, XueMei Xie, Yaping Lin, Zicong Chen, Suqing Zhao
Wound healing is a complex biological process that requires advanced wound dressings to promote healing. With the development of electrospinning technology, electrospun nanofibers have demonstrated superior application potential in wound...
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Engineering boronic acid-integrated lipid nanoparticles for precision glycan-mediated gene transfer

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00080K, Paper

Nirmal Chakraborty, Sourav Sarkar, Santanu Bhattacharya
Boronic acid-engineered lipid nanoparticles exploit cancer-associated sialylation to achieve selective and efficient gene delivery.
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Functionalized single-layered titanium carbide MXene based biosensor for selective H2O2 detection using covalently immobilized horseradish peroxidase

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00893C, Paper

Devarasu Mohanapriya, Vadakke Purakkal Sruthi, Senthilkumar Sellappan, Thenmozhi Kathavarayan
Hydrogen peroxide (H2O2) plays a significant role in biological and environmental systems. Therefore, it is crucial to develop an efficient biosensor towards H2O2 determination, which is important in environmental monitoring...
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Construction of self-assembled rhein–methotrexate nanoparticles and study of their synergistic anti-breast cancer mechanism

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00319B, Paper

Yubing Zhang, Jikai Yang, Jiaqi Xing, Chen Yang, Yuandi Yang, Qiufang Wang, Xintian Shao, Yanfeng Wang, Shuqin Ni, Jing Shi
This study developed a carrier-free nanomedicine MR, which can enhance the delivery effect of hydrophobic drugs, kill tumor cells by damaging mitochondria, and exhibit excellent synergistic anti-tumor activity.
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Transparent spin-coated chitosan–hyaluronic acid/MgO nanocomposite films for multifunctional open wound healing and visual wound assessment

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00710D, Paper

Elakkiya Krishnamoorthy, Balakumar Subramanian
Optically transparent wound dressings have emerged as advanced platforms for real-time monitoring of tissue repair while maintaining an optimal healing microenvironment.
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A bilayer theranostic hydrogel integrating visual pH monitoring with synergistic diabetic wound healing treatment

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00476H, Paper

Zhenkang Diao, Taotian Zhang, Yilin Jiang, Tianyuan Chen, Jiawei Lu, Mengxing Zhang, Dezheng Hu, Haozhou Shu, Qin Lin, Shiqi Huang, Ling Zhang
Diabetes-related chronic wounds are difficult to heal due to persistent bacterial infection, disrupted pH homeostasis, and prolonged excessive inflammation.
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Facile preparation, structural modulation, and bone-targeting of single-chain polypeptide nanoparticles

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00846A, Paper

Hang Xu, Wanying Wang, Jie Wu, Jiamin Yuan, Ziyuan Song
Single-chain polypeptide nanoparticles are synthesized from poly(L-lysine) and diacrylates through aza-Michael addition under mild conditions and functionalized with anionic moieties for bone-targeting.
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3D-printed lab-on-chip platforms for the detection of neurodegenerative diseases: opportunities and challenges

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00381H, Review Article

Subham Preetam, Richa Mishra, Shailendra Thapliyal, Sagar Mondal, Sarvesh Rustagi, R. K. Govindarajan, Soumya Pandit, Jutishna Bora, Nayan Talukdar, Muhammad Fazle Rabbee, Sumira Malik
3D-printed lab-on-chip platform for neurodegenerative disease detection, integrating microfluidic sample processing with advanced biosensing strategies for rapid biomarker analysis and diagnosis.
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Rationally designed mitochondria-impairing small molecule-enabled chemo-phototherapy to potentiate apoptosis and autophagy in cancer cells

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00591H, Paper

Asima Sahu, Phanindra Kumar, Anushka Kochar, Sweny Jain, Dhiraj Bhatia, Sudipta Basu
A mitochondria-targeted cyanine–NSAID conjugate enables imaging-guided chemo-phototherapy via ROS, heat, and Cox-2 inhibition in cancer cells.
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Sequential supramolecular assembly of tannic acid and phenylboronic acid copolymers enabling enhanced cancer immunotherapy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00283H, Paper

Anudari Batbayar, Ryotaro Ohashi, Yuto Honda, Haochen Guo, Makoto Matsui, Takahiro Nomoto, Yutaka Miura, Nobuhiro Nishiyama
Supramolecular polyphenol–boronate nanostructures (∼20 nm) orchestrate the antigen journey from lymphatic transport to DC-driven cross-presentation, eliciting potent CTL-mediated antitumor immunity.
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Encapsulation of a ruthenium–platinum photosensitizer into nanofibrous membranes for antibacterial photodynamic therapy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00671J, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Santanu Patra, Zisis Papadopoulos, Juan Sanz-Villafruela, Johannes Karges, Anzhela Galstyan
A Ru–Pt photosensitizer was encapsulated in electrospun PAN and PCL nanofibers, enabling light-driven antibacterial activity via singlet oxygen and superoxide generation. PAN showed superior stability and antifouling performance.
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An ultrasensitive visual detection platform for forchlorfenuron: from simulation-assisted hapten and antibody production to double-T immunochromatographic assay application

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00792A, Paper

Shuai Kou, Lingling Guo, Hua Kuang, Xinxin Xu, Chuanlai Xu, Aihua Qu
Forchlorfenuron (FCF), a widely utilized cytokinin-type plant growth regulator, poses a considerable threat to human health and ecological stability when overapplied.
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Drug Delivery with Fewer Fouls: Localized Antibiotic Release and Reduced Surface Biofouling with Glutathione-conjugated Hydrogels

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02919H, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Sonia Alavi, Karol Sokolowski, Catherine F Dial, Zackery P. Bulman, Richard A Gemeinhart
Systemic antibiotics are the standard of care for acute bacterial skin and skin structure infections (ABSSSI), but low drug perfusion at the site of infection and higher rates of antibiotic...
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A novel antibacterial dental resin composite material with quaternary ammonium salt modified mesoporous silica nanoparticles – an in vitro and in vivo animal study

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00491A, Paper

Bixiao Lin, Siyu Wu, Yimeng Zhang, Anchun Lu, Juan Zhong, Yutao Jian, Yunhua Chen, Ke Zhao, Xiaodong Wang
Secondary caries remains a leading cause of failure in resin composite restorations.
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NIR-triggered photothermal nanocomposite hydrogels integrating polydopamine carbon dots and dynamic multi-networks for infected wound healing

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00537C, Paper

Huanxuan Huang, Shiyang Liao, Dong Zhang, Hanwen Jiang, Qijia Liu, Keqing Xu, Yunlong Sun, Meidong Lang
A dynamic multi-network hydrogel leveraging NIR-triggered photothermal antimicrobial efficacy for infected wound regeneration.
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Decellularized scaffolds of porcine uterus reconstruct the endometrial microenvironment to promote uterine epithelial cell differentiation and organoid formation

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00637J, Paper

Jiekun Sun, Yuan Cheng, Danyang Song, Haiyue Xu, Yu Song, Hua Ni, Tingsheng Yan
Porcine uterine tissues were used to prepare decellularized scaffolds, and primary epithelial and stromal cells were extracted from the endometrium. The cells were co-cultured with the scaffolds to explore their recellularization and differentiation.
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A hybrid membrane-camouflaged CuS nanoplatform for synergistic nanotherapy of ovarian cancer via chemodynamic and sonodynamic effects

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00399K, Paper

Yuxin Jiang, Runzi Guo, Zhaojun Cui, Hongtao Hu, Lin Yuan, Xun Xu, Lin Lin, Xiuhui Wang, Wenjun Cheng
A hybrid membrane-coated CuS nanoplatform (CuS–BSA–PpIX@SR) modified with red blood cell membranes and SKOV3 tumor cell membranes was rationally constructed for targeted chemokinetic and sonodynamic synergistic therapy of ovarian cancer.
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Beyond ACE2: unveiling the receptor-mediated endocytic dynamic mechanism of SARS-CoV-2 at the single-particle level

J. Mater. Chem. B, 2026, 14,7331-7339
DOI: 10.1039/D6TB00299D, Paper

Xiaoyu Ma, Zhuang Zhang, Dandan Yang, Hui Wang, Hao Zhang, Yue Yang, Siying Li, Yuping Shan
SARS-CoV-2 VLPs exhibit a preference for BSG-mediated entry into ACE2-deficient HepG2 cells, despite DPP4 being more highly expressed.
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Poly(glutamic acid-block-tyrosine) peptides designed for gastrointestinal drug adsorption

J. Mater. Chem. B, 2026, 14,7280-7297
DOI: 10.1039/D6TB00121A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Hunter B. Wood, Joseph T. Dosch, Stella M. Trickett, Juhi Singh, Farin M. Weinger, Gerald J. Wang, Dazhe J. Cao, Stefanie A. Sydlik
Tunable poly(glutamic acid-block-tyrosine) peptides are synthesized and evaluated in vitro as pH-responsive adsorbents designed for efficient gastrointestinal drug capture.
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Preparation of a platycodin D microsphere gel and evaluation of its therapeutic effects on osteoarthritis in rats

J. Mater. Chem. B, 2026, 14,7253-7264
DOI: 10.1039/D6TB00220J, Paper

Linghui Qiao, Yingjie Ni, Dong Zhang, Jianyue Wu, Peiling Zhou, Pei Lu
Thermosensitive Platycodin D microsphere gel enables sustained intra-articular delivery and cartilage-protective therapy for osteoarthritis.
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Vibration-controlled extrusion-based 3D-printing of graphene-hydroxyapatite scaffolds: structural, mechanical, and electrical insights

J. Mater. Chem. B, 2026, 14,7340-7358
DOI: 10.1039/D6TB00755D, Paper

Mohammad Reza Dalir Abdollahinia, Milad Karimi, Amir Mohammad Ruiin, Hassan Nosrati
This study presents a comprehensive investigation into the effects of nonlinear vibrational regimes on the structural and functional integrity of reduced graphene oxide-hydroxyapatite (rGO-HA) scaffolds fabricated via extrusion-based 3D-printing.
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Effective gene editing of melanoma by delivery of Cas9 mRNA with highly branched poly(β-amino ester)

J. Mater. Chem. B, 2026, 14,7142-7149
DOI: 10.1039/D5TB02556G, Communication

Zhaowei Chu, Haiyang Yong, Zhili Li, Xi Wang, Bingjie Li, Cong Yan, Qinxiao Li, Yueran Tao, Dezhong Zhou, Songmei Geng
HPAE can effectively deliver Cas9 mRNA to enable gene editing of various melanoma cells.
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Hydrogel photopolymerization within microfluidic droplets for single cell encapsulation

J. Mater. Chem. B, 2026, 14,7124-7141
DOI: 10.1039/D6TB00258G, Review Article

Shiqi Lei, Xingdan Wang, Yan Liu, Yuheng Du, Zhihuan Li, Yajuan Guo, Renmeng Liu, Kaiwen Chen, Edward Ramsey, Kun Jiang, John Oakey, Zhongliang Jiang
Driven by innovations arise from material engineering and miniaturization technique, high-throughput microfluidic encapsulation promotes precise single-cell analysis to resolve cellular heterogeneity and hydrogel scaffolds for tissue engineering.
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Multifunctional pyrazino[2,3-g]quinoxaline derivative capable of acidochromic response, cancer cell imaging, and as an active layer for organic light-emitting diodes

J. Mater. Chem. B, 2026, 14,7359-7371
DOI: 10.1039/D6TB00439C, Paper

Neichoihoi Lhouvum, Sosmitha Girisa, Anil Kumar, Vinod Kumar Vishwakarma, Abhishek Rameshchandra Tiwari, Ajaikumar Bahulayan Kunnumakkara, Jwo-Huei Jou, Achalkumar Ammathnadu Sudhakar
Pyrazino[2,3-g]quinoxaline derivative capable of acid sensing, cancer cell imaging and usable as OLED.
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A GSH-scavenging and synthesis-blocking microneedle patch for augmenting photodynamic eradication of diabetic wound biofilms

J. Mater. Chem. B, 2026, 14,7372-7387
DOI: 10.1039/D6TB00905K, Paper

Haixia Zhang, Zhichao Ran, Yi Li, Jiaying Liu, Hangyu Wang, Junpei Mei, Peihang Song, Wenwei Liu, Chaoqun Liu, Kelei Guan, Ningning Song
A microneedle patch that both scavenges and blocks GSH synthesis boosts photodynamic biofilm eradication and wound repair.
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Near-infrared-triggered synergistic therapy with a Ru-based nanocomposite hydrogel for eradicating multidrug-resistant wound infections

J. Mater. Chem. B, 2026, 14,7211-7223
DOI: 10.1039/D6TB00808A, Paper

Zehui Xiao, Bingcong Ji, Jiangli Cao, Ting Du, Xinjun Du
A photothermal RBP hydrogel enables NIR-triggered berberine release, synergistic antibacterial action against MRSA and P. aeruginosa and accelerates infected wound healing with good biocompatibility.
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Combined improvement of the osteogenic and anti-inflammatory activities of Sr-doped bone cement modified with carboxymethyl cellulose

J. Mater. Chem. B, 2026, 14,7298-7315
DOI: 10.1039/D6TB00609D, Paper

Xiao-Dan Li, Da-Wei Yan, Hao-Hao Ren, Hai-Tao Peng, Kun Zhao, Qi-Yi Zhang, Yong-Gang Yan
CMC-modified Sr-doped bone cement promotes M2 macrophage polarization, osteogenic differentiation, biodegradation, and bone regeneration, showing promise for bone defect repair.
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S. aromaticum aqueous extract-derived carbon dots: a biosafe antibacterial nanocatalyst for water remediation

J. Mater. Chem. B, 2026, 14,7195-7210
DOI: 10.1039/D6TB00278A, Paper

Anurag Kumar Pandey, Sayan Mukherjee, Nantu Dogra, Tapan Kumar Nath, Sagar Pal, Santanu Dhara
Graphical schematics of clove extract-derived carbon dots (CECDs) and their application in water remediation.
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Construction of two drug-loaded gold nanoclusters@mesoporous polydopamine nanospheres and the synergistic treatment of abdominal aortic aneurysms

J. Mater. Chem. B, 2026, 14,7316-7330
DOI: 10.1039/D6TB00744A, Paper

Wenhao Li, Weina Zhang, Qin Huang, Mengjie Xu, Dehong Wu, Qi Hu, Dianwu Wu, Guangfu Yin, Zhongbing Huang
A targeting nanoplatform integrating NIR-II photothermal therapy and dual-drug release synergistically treats abdominal aortic aneurysm.
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Ultrasonic nanoreactors: porous nanomaterials as multimodal platforms for precision ultrasound-responsive therapy and sonotherapy in nanomedicine

J. Mater. Chem. B, 2026, 14,7078-7104
DOI: 10.1039/D6TB00612D, Review Article

Zepu Chang, Jinpu Yang, Shuaidong Huo, Yu Zhou, Pengkun Zhao
This review highlights recent advances in porous nanomaterials as ultrasonic nanoreactors for ultrasound-responsive therapy and sonotherapy, covering their synthesis, mechanisms, and applications.
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Supramolecular peptide hydrogels for the treatment of ocular diseases: from tissue replacements to drug delivery systems

J. Mater. Chem. B, 2026, 14,7105-7123
DOI: 10.1039/D6TB00761A, Review Article

Daowei Xia, Wenting Li, Jing Xie, Dongdong Zhou, Hao Su
This review presents advances in supramolecular peptide hydrogels for treating ocular diseases, including applications in tissue replacement and drug delivery systems, and discusses key challenges and future directions for clinical translation.
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Bismuth hybrid halide with dual inhibition against α-amylase and acetylcholinesterase probed by structural, vibrational, and theoretical analysis

J. Mater. Chem. B, 2026, 14,7224-7243
DOI: 10.1039/D5TB02912K, Paper

Assala Bahloul, Mehdi Messaad, Sirine Smaoui, Bassem Khemakhem, Mohamed Abdelhedi
A Bi(III) hybrid halide shows effective dual inhibition of α-amylase and acetylcholinesterase, rationalized by combined crystallographic, vibrational, and theoretical analyses.
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Lactate-sensitive nanomachines for enzyme-controlled drug delivery in cancer therapy

J. Mater. Chem. B, 2026, 14,7244-7252
DOI: 10.1039/D6TB00119J, Paper

Marta González-Jiménez, Teresa Moreno, Beatriz Mayol, Esther Garcia-Díez, Soraya Salido, Alfredo Sánchez-Sánchez, Paloma Martinez-Ruiz, Narcisa Martínez-Quiles, Diana Vilela, Reynaldo Villalonga
Preparation and characterization of L-lactate-responsive enzyme-powered mesoporous silica nanomachines for controlled drug delivery with promising cellular performance in the tumor microenvironment.
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Network modulation enables 3D-printed citrate-based polymer scaffolds with broadly tunable mechanical performance for regenerative engineering

J. Mater. Chem. B, 2026, 14,7265-7279
DOI: 10.1039/D6TB00602G, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Ni Chen, Nolan Schlessman, Rao Fu, Yonghui Ding
This work presents a facile network-engineering strategy for photopolymerizable citrate-based polymers that broadens the modulus–ductility window, enabling customized biomedical applications ranging from load-bearing to soft tissue engineering.
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Engineering copper nanoparticle/polysaccharide-immobilized cotton gauze for accelerated healing of Staphylococcus aureus-infected dermal wounds

J. Mater. Chem. B, 2026, 14,7179-7194
DOI: 10.1039/D6TB00543H, Paper

Madhusmita Sahoo, Tonmoy Banerjee, Shraddha Virkar, Sneha Das, Swati Biswas, Debirupa Mitra
Cu NP-modified cotton gauze possesses excellent in vitro bactericidal efficacy and surpasses commercial anti-infective silver dressings in its ability to accelerate wound healing with reduced inflammation and increased re-epithelialization.
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Controlling PEDOT:PSS electropolymerization for label-free optical recording of bioelectric potentials

J. Mater. Chem. B, 2026, 14,7150-7163
DOI: 10.1039/D6TB00816J, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Xuchen Ren, Jitong Ren, Yu Shi, Alexandra Kuhlman-Schneider, Koney Eungkon Kim, Zixin Zhang, Yuecheng Peter Zhou
Label-free optical recording of bioelectric potentials using conjugated electrochromic polymers provides a non-perturbative approach for detecting bioelectric activities.
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Conjugating M13 bacteriophage targeting folate receptor alpha with multiple photosensitizers: a flexible phototheranostic platform against ovarian cancer

J. Mater. Chem. B, 2026, 14,7164-7178
DOI: 10.1039/D5TB02844B, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Alena Kaltenbrunner, Andrea Martino, Michela Nigro, Andrea Carboni, Alessia Marconi, Nicolò Mercorelli, Manuele Di Sante, Chiara Di Donato, Annapaola Petrosino, Simona Corrà, Monica De Luise, Giuseppe Gasparre, Matteo Calvaresi, Alberto Danielli, Paolo Emidio Costantini, Matteo Di Giosia
Bioconjugation of Rose Bengal and Chlorin e6 onto an FRα-targeted M13 bacteriophage enables validated dual-light phototheranostic assessment and selective treatment of ovarian cancer.
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Recent progress in side-chain amino acid-based polymers: synthesis, self-assembly, and emerging biomedical applications

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00964F, Review Article

Jiaqi Gao, Shujie Xu, Jiazhen Niu, Aijia Chen, Qichao Sun, Xincheng Jiang, Guofeng Li, Xing Wang
Side-chain amino acid-based polymers (SCAAPs), as a class of functional polymeric materials constructed from natural amino acids or their derivatives, have garnered significant attention in recent years in the fields...
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Platelet Membrane Vesicle-Integrated Gelatin Scaffold as a Biomimetic Artificial Scab for Oral Ulcer Healing

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00552G, Paper

Xiangchun Luan, Ziyu Wang, Jie Lou, Yun Hu, Fang Qin, Ting Zhou, Xing Zhou, Lu Wang
Wound healing in the oral cavity remains clinically challenging because of the constantly moist, mechanically active, and bacteria-rich environment, where conventional dressings often fail to provide sustained protection or active...
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