RSC - J. Mater. Chem. B latest articles

Bio-Nano Architectures as Therapeutic Platforms: Mechanism-Driven Precision Anti-Infective Therapy for Periodontal Regeneration

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00197A, Review Article

Jiawei Du, Shizhe Li, Zishu Wang, Huijing Chen, Liangxiao Huang, Tongxuan Xin, Sitong Zhu, Wufu Zhu, Pengwu Zheng, Cunpeng Nie, qingshan Pan
Abstract Periodontitis affects nearly 50% of the global population. The main challenges are three major bottlenecks faced by traditional mechanical debridement and antibiotics: drug resistance, difficulty controlling deep infections, and...
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Preliminary study on targeted nanoparticles co-loaded with piperine and paclitaxel prodrug for ovarian cancer treatment

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02382C, Paper

Shengjie Wang, Ying Liao, Bowen Yang, Lin Li, Mingrong Xi
Combination chemotherapy incorporating natural products has emerged as an effective strategy to enhance anticancer efficacy while reducing systemic toxicity. Based on this, our study report a targeted, stimuli-responsive nanoparticle system...
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Redox-responsive nanoparticles for enhanced mRNA delivery: a comprehensive review

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00186F, Review Article

Ziyue Wang, Baiqiu Chen, Yuduo Gao, Chengfan Wu, Qi Shuai, Yunfeng Yan
Redox-responsive nanoparticles enable triggered mRNA release and enhanced cytosolic delivery by leveraging intracellular redox conditions. This review links material design to delivery outcomes and identifies translational barriers and strategies.
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Fabrication of functional polyethersulfone (PES) based materials for blood purification

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00231E, Review Article

Haoyu Tang, Xinju Jiang, Jiemin Wang, Chang-Sheng Zhao
Polyethersulfone (PES) based materials have been increasingly applied in the area of blood purification, because of their outstanding thermal, oxidative, physical/chemical stability, excellent mechanical properties, mild sterilization condition and ease...
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Alizarin-based soybean oil materials for the synthesis of 3D-photoprinted objects with efficient antibacterial properties

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00120C, Paper

Christine Elian, Fares Mouhoubi, Hassan Hayek, Sonia Lajnef, Fabienne Peyrot, Maxence Versace, Thi Huyen My Dang, Minh-Huong Ha Thi, Samir Abbad Andaloussi, Régis Moilleron, Katarzyna Starzak, Joanna Ortyl, Davy-Louis Versace
A biobased hydroxyanthraquinone dye derived from alizarin was shown to be an efficient visible-light photosensitizer for iodonium salt, leading high acrylate conversions (around 80%) up to 470 nm through a type II photoinitiation process.
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Amylase-Responsive Bilayer Film for Sustained Enzyme Delivery and ROS-Scavenging Therapy in Oral Ulcer Treatment

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02515J, Paper

Chengzhen Liu, Xiaoqing Liu, Qianer Zhu, Sen Lin, Xiaocong Ma, Yahui Li, Xiaohui Liu, Weiqiang Pan, Ruixue Lin
Oral ulcers are prevalent mucosal disorders, yet the clinical efficacy of current biomaterial-based therapies is often hindered by insufficient oral retention time and suboptimal drug bioavailability. To address these limitations,...
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Plasmonic gold–titania–curcumin nanoantennas for synergistic quadruple photodynamic/mild photothermal/radiodynamic/chemotherapy of non-small cell lung cancer

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02221E, Paper

H. Haghighi, H. Heli, A. Ketabi, R. Dehdari Vais, P. Faghani-Eskandarkolaei, A. Rahi, M. Ziasistani, N. Sattarahmady
Quadruple photodynamic/mild photothermal/radiodynamic/chemotherapy of non-small cell lung cancer was performed using novel synthesized gold–titania–curcumin nanoantennas. Quadruple therapy demonstrated synergistic therapeutic effects.
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H2O2 responsive rhodamine-based probe for monitoring early-stage diabetes diagnosis

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02687C, Paper

Moumita Mondal, Pravat Ghorai, Asmita Samadder, Stefan A. Freunberger, Priyabrata Banerjee
Rhodamine-derived probe without recognition site reported for monitoring H₂O₂ in food and physiological cells and tissue.
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Hierarchically engineered injectable hydrogels loaded with polyphenol for enhanced wound healing and tissue regeneration

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02944A, Paper

Prasanna Kumari Barani, Indu Yadav, Manisha Meena, Ankur Singh, Aneri Joshi, Devanshi Gajjar, Sriram Seshadri, Dhiraj Bhatia, Mukesh Dhanka
The injectable SCLP hydrogel is an 'all-in-one' lab-synthesized polymeric network. It mimics the ECM and delivers multiple functionalities to boost tissue regeneration and heal full-thickness wounds.
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Graphene-Based Porous Hydrogels with Tunable Piezoresistive Response for Wearable Strain Sensing

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02688A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Nishadi M Bandara, Khandaker Umaiya, Cesar E. Gouveia, Michael Joseph Joyce, Douglas Adamson
This study reports the synthesis of porous hydrogels templated by self-assembled, percolating graphene networks formed through the spontaneous exfoliation of graphite at oil-water interfaces.The resulting graphene-stabilized emulsions yield an open-cell...
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In Vitro Models of Oxidative Stress, Mitochondrial Dysfunction, and Inflammation for Evaluation of Neuroprotective Biomaterials

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00226A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Fucen Luo, Thelma Akanchise, Borislav Angelov, Angelina Angelova
Neurodegenerative diseases arise from intertwined mechanisms involving oxidative stress, mitochondrial dysfunction, and neuroinflammation, leading to progressive neuronal loss. Developing in vitro models that reproduce these distinct yet interconnected pathological features...
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Near-Infrared Reinforced Alginate-Tyramine-Curcumin Gels for Alleviation of Osteoarthritis in an ACLT Murine Model

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB00975H, Paper

Yao-Tung Tsai, Yu-Wen Tseng, Shen-Han Wu, Yan-Ting Chen, Hui-Wen Chiu, Hieu Trung Nguyen, Chueh-Hung Wu, Andrew E. Y. Chuang, Wen-Shiang Chen, Chih-Kuang Chen
Osteoarthritis (OA) poses a significant challenge because of its complex pathology, involving factors such as hypoxia, inflammation, angiogenesis, oxidative stress within mitochondria, and fibroblast-driven instability of fibrocartilage. Traditional scaffold-based treatments...
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Mineralization of Bouligand-structured collagen matrices derived from fish scales with enhanced mechanical properties and biocompatibility

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00200E, Paper

Huanhuan Zhang, Yin Liu, Ying Huang, Wenxuan Wang, Liangyu Guo, Hao Xie, Hang Ping, Weijian Fang, Zhengyi Fu
Biological materials often combine both high strength and toughness, with their exceptional mechanical properties relying on multi-scale hierarchical architectures. Investigating the biomineralization processes of such materials provides valuable inspiration for...
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Quercetin-functionalized gold/silver nanoparticles with tunable antibacterial selectivity for bacterial infection treatment

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02885J, Paper

Yu-chen Xie, Li-yun Ma, Yuxi Xiao, Xin Wang, Xu Yu, Ming Jiang, Li Xu
Selective antibacterial use is a key strategy for delaying drug resistance and a principle of precision antibacterial therapy. Developing selective antibacterial agent is highly desired for this purpose. In this...
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Functionally Graded Bilayer Polyurethane Sponge with Sequential Stage-Adaptive Capabilities for Full-Cycle Repair of Infected Wounds

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00571C, Paper

Qiusheng Wang, Chongyang Mai, Yue Li, Yunpeng Wang, Bin He
The management of full-thickness infected wounds remains a major clinical challenge, largely due to the paucity of multifunctional dressings capable of spatiotemporally coordinated regulation across the entire healing cascade. To...
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Rational design of microfluidic templated HA-LPEI nanogels for the targeted delivery of doxorubicin

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02518D, Paper

Open Access

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Emanuele Limiti, Eleonora D’Alessandro, Alessio Bucciarelli, Sofia Raniolo, Pamela Mozetic, Elisa De Luca, Enrico Domenico Lemma, Francesco Basoli, Giuseppe Gigli, Fabio Pizzetti, Emanuele Mauri, Filippo Rossi, Marcella Trombetta, Sara Maria Giannitelli, Alberto Rainer
This study explores the implementation of a response surface methodology supporting the rational design of hyaluronic acid (HA) - linear polyethyleneimine (LPEI) nanogels via droplet-based microfluidics for the targeted delivery of doxorubicin.
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Eggshell-derived Nanoparticles Accelerate Wound Healing

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00239K, Paper

PROMA NAGCHOWDHURY, Swapnali Londhe, Sanchita Tripathy, Yogesh Chandra, Chittaranjan Patra
The chronic wounds (a silent epidemic) and its adverse impact is a serious global health problem. Normal wound healing is a complex, and processes through a series of four interconnected,...
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Polymersome-based targeted delivery of TLR7/8 agonists enhances cancer immunotherapy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00050A, Paper

Shaoqiong Liu, Ser Yue Loo, Jian Hang Lam, Wei Xiang Poh, Yan Jun Lee, Suet Li Chew, Melvin Liew, Salmah Humairoh Binte Zamri, Katherine Schultheis, George Griesgraber, Mark Tomai, Madhavan Nallani
Polymersomes efficiently encapsulate TLR7/8 agonist 3M-060, offering robust stability at 4 °C and sustained release. This targeted delivery platform enhances efficacy and safety of 3M-060, extending its clinical potential in cancer immunotherapy.
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Precision mitochondrial reprogramming via a ROS-amplifying Pt(IV) nanoplatform potentiates tri-modal therapy to overcome Pt resistance in HCC

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02428E, Paper

Ruoning Qian, Junqing Hou, Hongjun Guo, Qiang Zhang, Jiamin Lin, Yitian Zhou, Zhiqiang Bi, Jiajia Shen, Xi Yang, Shanshan Wang, Zhengguang Zhang, Ruogu Qi
A multi-responsive nanoplatform co-delivers cisplatin, artesunate, and Ce6 for combined chemo/chemodynamic/photodynamic therapy, reprogramming mitochondrial homeostasis to overcome cisplatin resistance and suppress liver cancer with improved safety.
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Functional 3D bioprinting with GelMA/CMCh bioinks: a supportive microenvironment for stromal keratocyte maintenance and potential corneal stromal repair

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02459E, Paper

Renuka Vijayaraghavan, Sravanthi Loganathan, Ravi Babu Valapa
A photocrosslinkable GelMA/CMCh bioink enabled fabrication of transparent, mechanically stable 3D printed corneal scaffolds that promote stromal keratocyte viability and phenotype preservation.
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Intervention of hIAPP amyloid aggregation by smart posttransmuting anti-amyloidogenic peptidomimetics

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02851E, Paper

Altaf Hussain Kawa, Biswadeepak Satapathy, Shinjini Bhattacharya, Sachin Kumar, Bhubaneswar Mandal
hIAPP, human islet amyloid polypeptide, aggregates have been implicated in the development of type 2 diabetes mellitus (T2DM). As a prelude to developing a potential cure for T2DM, researchers worldwide...
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Multifunctional ginsenoside Rg3-integrated liposomes for synergistic chemo-photothermal-immunotherapy against multidrug-resistant breast cancer

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00024J, Paper

Wuyan Xie, Kai Wang, Qin Zhou, Haihua Zhou, Qing Zhu, Dan Wu, Wei Shen
To address multidrug resistance (MDR) in breast cancer, a multifunctional liposome (RID-LPs) was developed by replacing cholesterol with ginsenoside Rg3 and incorporating DSPE-PEG2000 for prolonged systemic circulation. This nanoplatform encapsulates...
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MMP-Responsive Bioactive Glass-Incorporated Hydrogels with Enhanced Antibacterial and Angiogenic Performance for Infected Wound Healing

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00096G, Paper

Wenjia Shao, Min Xing, Linlin Zhao, Xue Ke, Kuicai Ye, Shuhan Chen, Hairong Liu, Jiajun Qiu, Xuanyong Liu
Chronic wounds are difficult to heal due to complex pathological features such as bacterial infection, abnormal expression of matrix metalloproteinases (MMPs), and impaired angiogenesis, posing a serious threat to public...
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Indole-Bipyridyl Fluorophores as Dual-Functional Probes for Endoplasmic Reticulum Imaging and Zn²⁺ Sensing in Live Cells

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02797G, Paper

Mohini Ghorpade, Sayan Bera, Gayatri A Bhattad, Paramasivam Mahalingam, Sriram Kanvah
The endoplasmic reticulum (ER) plays a central role in protein folding, lipid biosynthesis, and calcium regulation, and its dysfunction is closely linked to diseases such as cancer, neurodegeneration, and metabolic...
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Photothermally triggered silk fibroin microneedles with coordinated gallic acid–iron networks for synergistic infected burn wound therapy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00149A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Wang Sun, Rui Xu, Wenshuya Li, Ziyan Chen, Mengting Yin, Haibo Liu, Feng Chen, Haijian Ni, Xinyu Zhao
Silk fibroin microneedles with gallic acid-iron networks were made for infected burns. NIR-triggered photothermal antibacterial action and sequential bioactive release provide synergistic antioxidant, anti-inflammatory and regenerative effects.
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Magnetic borylated conjugated polymer nanoparticles for deep-red optical and lifetime imaging

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00192K, Communication

Open Access

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Struan Bourke, Yurema Teijeiro Gonzalez, Patrick Bergstrom Mann, Daniel Luke Crossley, Laura Urbano, Lea Ann Dailey, Klaus Suhling, Michael L. Turner, Michael J. Ingleson, Mark Green
In this communication, we report the development of water-dispersible, deep-red emitting conjugated polymer based nanoparticles for multimodal optical and MR imaging.
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Stress relaxation timescale and hydrogel network connectivity regulate neural progenitor cell stemness and differentiation

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02537K, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Lauren E. Brown, Daphne Bakker, Ping Zhou, Christopher M. Madl
A family of modular recombinant protein–synthetic polymer hybrid hydrogels reveals that stress relaxation timescale and network connectivity regulate neural progenitor cell stemmness.
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Keratinocytes biocompatibility, antibacterial and antioxidant properties of porous coacervate phosphate glass fibres and powders loaded with cerium and clove oil: a comparative study

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02254A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Zarrin Moghaddam, Rahul Sanwlani, Eveliny Tomás Nery, Irem Unalan, Oluwadunmininu Okude, Agron Hoxha, Charlotte A. Berry, Kavin Hettiarachchilage, Steven J. Hinder, Mark A. Baker, Monica Felipe-Sotelo, Alessandra Pinna, Jorge Merino-Gutierrez, Aldo R. Boccaccini, Patrizia Camelliti, Daniela Carta
Porous coacervate phosphate glasses fibres and powders loaded with gallium and clove oil for wound healing applications.
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SAXS study of electric field-induced microstructural evolution in a polyaniline-based conductive hydrogel

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00211K, Paper

Open Access

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Liu Tang, Yining Sun, Robert F. Schmidt, Clement Blanchet, Michael Gradzielski
SAXS shows the structural evolution of conductive hydrogels (quaternized chitosan grafted with PANI, crosslinked with PVA and boric acid). Electrical stimulation transforms the hydrogel to a denser structure with much reduced mechanical properties.
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Oral liposomal co-delivery of ultrasmall ceria and 5-aminosalicylic acid alleviates DSS colitis via ROS scavenging and microbiome remodeling

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00173D, Paper

Jiahao Du, Yunyun Sun, Dong Yu, Shengwei Lu, Simin Yu, Mei Wang, Guoqing Zhou, Songxin Xu, Lei Zhang, Yefei Zhu, Longxiang Zhou
Oral CeLA alleviates colitis by scavenging ROS, reducing TNF-α/IL-6, restoring tight junctions and barrier integrity, and modulating the gut microbiota.
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Manganese-activatable nano-hydroxyapatite nanoparticles as self-adjuvanting STING activators for synergistic melanoma therapy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02759D, Paper

Su Xiang, Rong Yuan, Yunjia Rao, Jun Cao, Xiangpeng Jin, Liang Cheng, Huan Cao, Zhu Chen
nHA–Mn acts as a self-adjuvanting nanoplatform through the synergistic effect of Mn²⁺ and nHA to enhance mitochondria-mediated cytotoxicity and activate a stronger anti-tumor immune response, thereby achieving effective melanoma suppression.
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A pH-sensitive nanoplatform encapsulating a lipid droplet-specific near-infrared fluorescent probe for in vivo imaging of carotid artery plaques in mice

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02936H, Paper

Ying Zhang, Tianyi Qu, Fengming Wu, Ming Chen, Zheng Chai, Shufen Li, Weihua Zhuang, Mao Chen
A lipid droplet (LD) activated pH responsive nanoplatform (ZY-P1-PMEA NP) has been developed for real-time and accurate in vivo diagnosis of ApoE^−/− mouse carotid plaques.
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Nanotoxicological evaluation of surface engineered WS2 quantum dots in male and female Wistar rats for targeted nucleus imaging and photothermal therapy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02619A, Paper

Barkha Singh, Rohan Bahadur, Priyanka Maske, Dipty Singh, Ajayan Vinu, Rohit Srivastava
PEGylated WS₂ quantum dots enable nuclear imaging and photothermal ablation with low cytotoxicity and no acute toxicity in male/female rats, with sex-dependent biodistribution.
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Freezing-Induced Ice–Polymer Structuring Enables Tough, Additive-Free Hydrogels Under Extreme Cold Conditions

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02063H, Paper

Open Access

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Jialun Wei, Dong Zhang, Yung Chang, Athena B Santi, Amanda Gomez, Lijin Wang, Gabriela Romero, Jie Zheng
Designing hydrogels that retain mechanical robustness under subzero conditions remains a major challenge for applications in bioengineering, soft robotics, and extreme-environment systems. In this study, we introduce a fundamentally new...
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Blue light-activated berberine–gentamicin combination breaks down biofilms in diabetic foot ulcers

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00081A, Paper

Open Access

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Ariana S.C. Gonçalves, Miguel M. Leitão, Manuel Simões, Anabela Borges
Blue light-activated berberine-gentamicin synergistically eradicates polymicrobial biofilms in diabetic foot infections.
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Multicolor STED Imaging of Cells and Extracellular Vesicles using Xanthene-conjugated Polymer Dots

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00345A, Paper

Peixiang Li, Kehua Tang, Yachen Ying, Long Chen, Qin Shentu, Yating Xiao, Lubin Qi, Ren Cai, Qiongzheng Hu, Jiantao Ping, Xiaohong Fang, Yifei Jiang
Stimulated emission depletion (STED) nanoscopy enables imaging beyond the optical diffraction limit. However, its performance critically depends on the quality of fluorescent probes. In particular, multichannel STED imaging imposes stringent...
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Correction: Designed peptide-grafted hydrogels for human pluripotent stem cell culture and differentiation

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB90048H, Correction

Open Access

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Ting Wang, Qian Liu, Yu-Tang Chang, Jun Liu, Tao Yu, Kailibinuer Maitiruze, Lee-Kiat Ban, Tzu-Cheng Sung, Suresh Kumar Subbiah, Remya Rajan Renuka, Shih Hsi Jen, Henry Hsin-Chung Lee, Akon Higuchi
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Chondroitin sulfate in osteoarthritis treatment: a twenty-year bibliometric analysis and comprehensive review

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00057F, Review Article

Ainikaer Abulaiti, Zhen Liu, Shi Qiu, Maihemuti Yakufu, Paerhati Wahafu, Maerdan Maimaitiming, Jiashun Li, Zheng Wang, Yaqin An, Munisha Abulikemu, Kaishaer Baihetiyaer, Deyu Li, Li Shu, Guohua Li, Yuxiang Zhang
Analysis of 2004 articles outlines chondroitin sulfate's evolving trajectory in osteoarthritis treatment across three phases: pharmacological treatment, tissue engineering and biomaterials, and precise drug delivery.
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3D printed biomimetic PEEK/HA scaffolds induce cranial bone regeneration

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02807H, Paper

Haojia Li, Luyang Liao, Yushuan Jia, Yingyuan Zhang, Kai Zhang, Xingdong Zhang, Xiangdong Zhu, Bo Yuan
The repair of critical-sized cranial defects resulting from trauma, congenital malformations, or surgery remains a significant clinical challenge.
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Mg2+-regulated directional assembly of enamel-like fluorapatite nanoarrays reinforced via amorphous intergranular phases for accelerated mineralization

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00328A, Paper

Benxi Xu, Bingyu Xue, Jiangyu Yi, Junming Wu, Yidi Li, Zhengyi Fu, Kun Wang
Mg²⁺-regulated directional assembly of enamel-like fluorapatite nanoarrays, reinforced by Mg²⁺-rich amorphous intergranular phases, enables rapid fabrication under ambient conditions while achieving outstanding mechanical robustness.
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Interfacial redox transformation and phytochemical capping drive the formation and protective bioefficacy of Phyllanthus acidus-derived selenium nanoparticles against Aeromonas hydrophila infection in zebrafish

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02675J, Paper

Anusuya Nagaraj, Sudhakar Poda, Vinay Viswanath Konduri, Lokanadhan Gunti, Naveen Kumar Kalagatur
This study demonstrates the synthesis of selenium nanoparticles (PAF-SeNPs) through interfacial redox transformation using Phyllanthus acidus fruit extract as a reductant and stabilizing matrix.
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Advanced nanoplatforms for precise intervention of synovial inflammation in rheumatoid arthritis

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00088F, Review Article

Weidong Luo, Ming Han, Qiuyu Cai, Yuting Tan, Yang Gao, Hongju Zhou, Zhengbao Yang, Raul D. Rodriguez, Yuanjiao Tang, Lang Ma
This review proposes a logical framework centered on FLS and MLS and integrates dual-cell regulation, adaptive microenvironment-response, and immune-metabolic reprogramming strategies.
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Facile electroless displacement plating of mesoporous gold films as robust and reproducible SERS substrates for biosensing

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02458G, Paper

Daiki Masaoka, Kaito Kono, Mostafa Kamal Masud, Carlos Salomon, Md Shahriar A. Hossain, Asep Sugih Nugraha, Joel Henzie, Yusuke Asakura, Emtiaz Ahmed, Mandy Hei Man Leung, Yusuke Yamauchi
Facile electroless displacement plating yields mesoporous gold films on copper substrates with high surface area and dense hotspots, enabling reproducible SERS biosensing using antibody-functionalised nanotags for interleukin-1β detection.
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Polarity-triggered high-contrast fluorescent imaging of lipid droplets via a naphthalimide fluorophore

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02902C, Paper

Yuanqian Yang, Haixu Wang, Xiaoqian Gao, Yao Fu, Hong Wang, Mingming Xing, Yao Fu, Fangyun Xin, Ying Tian, Yong Tian, Xiaoling Zhang
Lipid droplets (LDs) are complex and dynamic organelles and involve in a variety of biological processes. Notably, some severe diseases are usually initiated by aberrant alterations of LDs. Consequently, the...
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Targeting xanthine oxidase degradation via PROTAC technology for the treatment of hyperuricaemia

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00078A, Paper

Xue Dong, Lin Wang, Sijia Lin, Ziyi Wang, Xueyong Qi, Jin Cao, Jing Zhang, Lin Wu, Song Shen
Hyperuricemia, characterized by an elevated serum uric acid level due to the abnormal xanthine oxidase (XOD)-mediated uric acid production, is generally associated with multiple systemic disorders. In this study, XOD-targeting...
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Universal Gd3+-based Hydrogel Matrix for Room-Temperature Phosphorescence Inducing

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00011H, Paper

Jiazhuo Li, Ying Wang, Zhiyun Lu, Peng Wu
Room-Temperature Phosphorescence (RTP) is difficult to achieve in aqueous media, due to the inherent and serious quenching of the excited triplet state by O2 and H2O. Herein, we reported RTP...
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Imidazolinone-based fluorophores: from green fluorescent proteins to confinement strategies and bioinspired materials design

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02566D, Review Article

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Sifan Ji, Sébastien Lecommandoux, Colin Bonduelle, Chloé Grazon
Inspired by GFP, synthetic imidazolinone fluorophores use covalent or non-covalent confinement to suppress twisting, boosting brightness and stability, and enabling advanced applications in imaging, sensing, photocatalysis, and photonic devices.
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A Mitochondria-Targeting ICT Probe for Dual-Functional Peroxynitrite Sensing: From Live-Cell Imaging to Serum Model and Plasma-Activated Water Monitoring

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02648B, Paper

Xinyue Yang, Yongqi Tian, Bo Liu, Kangkang Li, Guoming Zou, Ling He, Jing Zeng, Yingbo Wang
Peroxynitrite (ONOO–) plays dual roles as a key oxidative stress marker in pathological processes and as a critical bactericidal agent in plasma-activated water (PAW). However, real-time tracking and monitoring of...
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Mechanisms and clinical applications of ozone and ozonated oil as antimicrobial systems

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02749G, Review Article

Shuoxuan Wang, Mingxi Li, Yang Liu, Chuan Chen, Fang Yang
With the growing severity of antibiotic resistance, the development and application of novel antimicrobial agents are becoming increasingly urgent. Since the application of ozone in blood purification in the 19th...
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In-situ Hydrothermal Synthesis of Zeolite-PVA Hemostatic Sponge and Its Rapid Hemostasis in a Lethal Massive Hemorrhage Model

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00307A, Paper

Ni Zhu, Kun Li, Siyi Cao, Chaojie Shi, Liping Xiao, Fei Pan, Yifeng Shi, Jie Fan, Tanshi Li
Efforts to improve the survival rates of patients with severe hemorrhage are highly dependent on hemostatic materials to achieve rapid and timely hemostasis. Zeolites have demonstrated their superb procoagulant property...
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A Suturable Multilayered Fibrous Scaffold Loaded with α-Ketoglutarate for Enhanced Bone Regeneration

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00264A, Paper

Aolong Li, Tingting Ma, Siluo Dai, Yi-Ran Li, Zhengyang Qin, Jidong Li, Yubao Li
The successful application of guided bone regeneration (GBR) membranes requires overcoming the limitations of traditional materials in terms of active biological regulation and clinical operability. To address this, following a...
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Integration ferrihydrite prepared by an innovative method with oxidized activated carbon to construct a novel cascade nanozyme platform for inflammation therapy

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02793D, Paper

Lvyao Yang, Tingyu Jing, Wenjing Wei, Guixia Ling, Peng Zhang
Inflammatory diseases are typically characterized by relatively high levels of reactive oxygen species (ROS). These persistent and abundant ROS cause irreversible damage to the body by directly destroying nucleic acids,...
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A cascade-functionalized ZnCdS/Ce-MOF composite gate coupled with self-replicating catalytic hairpin assembly for OPECT sensing of imidacloprid

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00112B, Paper

Bo Zhang, Deguo Hou, Xinmeng Chen, Dianping Tang, Chen Zhang, Zhenli Qiu, Yiting Chen
A high-performance organic photoelectrochemical transistor (OPECT) sensor was successfully constructed based on a ZnCdS/Ce-MOF heterojunction gate integrated with a self-replicating catalytic hairpin assembly (SRCHA) signalamplification strategy, enabling ultrasensitive and highly...
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Tirapazamine-Assembled Phototherapy Agent for Combined Chemotherapy, Photodynamic Therapy, and Photothermal Therapy of Hepatocellular Carcinoma in Mice

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00126B, Paper

Liang Chen, Haiou Chen, Li Liu, Pang E, Yuanyu Tang, Wei Ma, Jierou Huang, Yongyin Li, Minhuan Lan, Yongjun Zhou
Hypoxia is a pervasive and spatially heterogeneous hallmark of hepatocellular carcinoma (HCC) that drives therapy resistance and motivates the use of hypoxia-activated prodrugs (HAPs) such as tirapazamine (TPZ). To synchronize...
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Correction: Biodegradable polyurethane nerve conduits functionalized with NDP-MSH-loaded self-assembling peptide hydrogels for peripheral nerve regeneration

J. Mater. Chem. B, 2026, 14,4197-4197
DOI: 10.1039/D6TB90041K, Correction

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Junhong Li, Jinghan Wang, Xirui Long, Jingjing Lin, Mi Su, Chang Ding, Rongxu Lin, Feng Luo, Jiehua Li, Yanhui Liu, Yanchao Wang, Hong Tan
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Galactose-decorated lipid nanoparticle-mediated delivery of a selective NLRP3 inhibitor attenuates hepatic inflammation in metabolic dysfunction-associated steatotic liver disease

J. Mater. Chem. B, 2026, 14,4173-4182
DOI: 10.1039/D5TB02289D, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Chunyan Niu, Wen Gao, Mei Tan, Yue Chen, Yongqiang Shi, Yan Geng, Huayi Tao, Zhenjiang Xu, Tingting Zhang, Jinming Yang
The MCC950-loaded formulation effectively reduced the expression of inflammatory regulators and cytokines associated with the NF-κB/NLRP3-related signaling pathway.
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Correction: Au/Mn nanodot platform for in vivo CT/MRI/FI multimodal bioimaging and photothermal therapy against tongue cancer

J. Mater. Chem. B, 2026, 14,4195-4196
DOI: 10.1039/D6TB90034H, Correction

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Zhe Yang, Yueqi Zhao, Yang Li, Lei Song, Yangliu Lin, Kaimeng Liu, Yujia Zhang, Andrei V. Zvyagin, Linan Fang, Yuanqing Sun, Bai Yang, Quan Lin
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A dual responsive hydrogel with a single-atom copper nanodrug for precision and sustained tumor therapy

J. Mater. Chem. B, 2026, 14,4144-4157
DOI: 10.1039/D5TB02644J, Paper

Zhaomin Tang, Yaning Ou, Yudong Wang, Kanglin Chen, Wenxin Liao, Junbo Song, Yuhua Xiang, Pinjia Zhong, Dongliang He, Donglian Liu, Qiuye Jin
A dual-responsive hydrogel (Cu-SAC@TP) encapsulating single-atom copper nanozyme was developed. In acidic TME, Cu-SAC self-supplies H₂O₂ and catalyzes Fenton-like reactions to generate toxic ˙OH and ¹O₂, achieving 75% tumor suppression.
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A–D–A–D–A structured organic semiconductor liposomes for NIR-II fluorescence imaging and surgical navigation of lymph node metastasis

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00155F, Paper

Qian Jiang, Xuqing Ying, Xufeng Lu, Chunjie Wei, Kaiye Fu, Shaoliang Yan, Zhifa Shen, Jiaxi Ru, Ganhua Guo
Fluorescence-guided surgery enables precise intraoperative “mapping” of malignant tissue, allowing surgeons to identify and excise small or occult lesions while preserving healthy tissues, reducing recurrence/metastasis risks and promoting recovery.
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The emerging role of magnesium in peripheral nerve regeneration: biomaterial design, mechanistic basis, and translational barriers

J. Mater. Chem. B, 2026, 14,3994-4017
DOI: 10.1039/D6TB00116E, Review Article

Khandoker Asiqur Rahaman, Yuna Jung, Md Lemon Hasan, Akhmad Irhas Robby, Shihab Uddin, Hyung-Seop Han
Mg-based biomaterials have demonstrated promise by providing multiple functions, from mechanical support to injury repair, by promoting axonal growth, Schwann cell activity, angiogenesis, and modulation of key neuroinflammation pathways. Created with BioRender.com
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Therapeutic potential of bile acids and synthetic strategies of their incorporation into polymeric drug delivery systems

J. Mater. Chem. B, 2026, 14,3947-3971
DOI: 10.1039/D5TB02481A, Review Article

Dawid Szymczuk, Agnieszka Z. Wilczewska, Katarzyna Niemirowicz-Laskowska, Pawel Misiak, Ryszard Lazny, Karolina H. Markiewicz
This review discusses the bioactivity of bile acids and the synthetic strategies used to integrate them into polymers to create drug delivery systems with enhanced therapeutic performance.
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Bio-based macromolecular polythiourethane plasticizers enable sustainable and migration-resistant flexible films for intelligent packaging

J. Mater. Chem. B, 2026, 14,4048-4058
DOI: 10.1039/D5TB02760H, Paper

Hong-Long Zheng, Wen-Tao Wang, Ting Liu, Ke Ma, En Zheng, Wen-Wu Zhang, Ke-Zheng Chen, Sheng-Lin Qiao
Here, a lipoic acid-derived macromolecular polythiourethane plasticizer, LPU, is developed as a sustainable and migration-resistant flexible film for intelligent packaging.
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Injectable oligomer-cross-linked chitosan hydrogels for biomedical applications

J. Mater. Chem. B, 2026, 14,4080-4097
DOI: 10.1039/D5TB02401C, Paper

Open Access

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Iram Maqsood, Hafiz Awais Nawaz, Ketpat Vejjasilpa, Caroline Kohn-Polster, Jan Krieghoff, Alexandra Springwald, Michaela Schulz-Siegmund, Michael C. Hacker
Injectable oligomer-cross-linked chitosan hydrogels, designed to emulate the extracellular matrix (ECM) in tissue engineering, are conventionally formed through physical gelation.
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Electrospun nanofibers and electrical stimulation: a synergistic approach for chronic wound management

J. Mater. Chem. B, 2026, 14,3910-3931
DOI: 10.1039/D5TB02803E, Review Article

Open Access

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Jéssica Lopes, Maria Teresa Cruz, Fernando Ramos, Juliana R. Dias
Electrospun conductive wound dressings enable localized electrical stimulation at the injury site, promoting antibacterial activity and enhancing tissue regeneration. This strategy accelerates chronic wound healing by restoring bioelectrical signalling and improving cellular responses.
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Drop-on-demand antimicrobial printed coatings loaded with a dehydroabietic acid derivative to prevent orthopedic implant infections

J. Mater. Chem. B, 2026, 14,4037-4047
DOI: 10.1039/D5TB02177D, Paper

Open Access

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David Martínez-Pérez, Inés Reigada, Jayendra Z. Patel, Jari Yli-Kauhaluoma, Leena Hanski, Michał Srebrzynski, Maciej Spychalski, Emilia Choińska, Adyary Fallarero, Wojciech Święszkowski
Microvalve DOD printing enables precise DHA1-loaded PLGA-PEG coatings on titanium, preventing S. aureus biofilms, providing sustained 24 h antimicrobial activity, and maintaining high cytocompatibility for infection-resistant orthopedic implants.
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Discovering naturally occurring antifreeze peptides from microbiome by integrating protein language models and molecular dynamics simulation

J. Mater. Chem. B, 2026, 14,4059-4069
DOI: 10.1039/D5TB02758F, Paper

Open Access

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Ibrahim A. Imam, Trevor Morey, Yuexu Jiang, Duolin Wang, Dong Xu, Qing Shao
Antifreeze peptides inhibit ice crystal growth and recrystallization, and are promising components of cryoprotective formulations for cell, tissue, and food preservation, as well as anti-icing surface coatings.
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Green synthesis of a bacitracin@Ag–CeO2 nanocomposite@hydrogel for dual antibiofilm and anti-inflammatory therapy against MRSA wound infections

J. Mater. Chem. B, 2026, 14,4125-4143
DOI: 10.1039/D5TB02286J, Paper

Raman Krishnamoorthi, Chien-Yu Hsiao, Yi-Ping Chou, Abdullah Alshetaili, Pambayan Ulagan Mahalingam, Jia-You Fang
Bac@Ag-CeO₂@PSG shows potent anti-MRSA, antibiofilm, antioxidant, and anti-inflammatory effects, accelerating wound healing. Treatments with Bac@Ag-CeO₂ and Bac@Ag-CeO₂@PSG outperformed Ag-CeO₂ NCs and free bacitracin in healing efficiency.
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A microenvironment-responsive hydrogel with photothermal, antioxidant, and neuroregenerative functions for diabetic chronic infectious wound healing

J. Mater. Chem. B, 2026, 14,4158-4172
DOI: 10.1039/D5TB02313K, Paper

Zan Chen, Ye Wu, Heng Gong, Yunfeng Tang, Dong Wang, Zhen Wang, Ye Wang, Guanglin Wang, Wei Lin, Renliang Zhao, Cheng Zheng, Xiangtian Deng
Diabetic chronic infectious wounds (DCIWs) remain a clinical challenge due to impaired vascularization, persistent infection, and excessive oxidative stress.
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MXene-loaded hydrogels for tissue regeneration: a review of recent advances and future perspectives

J. Mater. Chem. B, 2026, 14,3972-3993
DOI: 10.1039/D5TB02696B, Review Article

Satheesh Selvaraj, Rajasekaran Subbarayan, Ankush Chauhan, Majid Jabir, Suresh Ghotekar
MXene-loaded hydrogels represent a promising class of multifunctional biomaterials that combine the remarkable physicochemical properties of MXenes with the adjustable structure and biocompatibility of hydrogels for tissue regeneration.
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Stimuli-responsive phenothiazine–tetraphenylethylene hybrid luminogens: mechano- and piezochromic properties with anticancer applications

J. Mater. Chem. B, 2026, 14,4183-4194
DOI: 10.1039/D5TB02340H, Paper

Ramakant Gavale, Siddharth Singh, Faizal Khan, Srija Mukherjee, Jiayi Yang, Guanjun Xiao, Bo Zou, Hem Chandra Jha, Rajneesh Misra
Mechanochromic and piezochromic luminogens represent a class of stimuli responsive materials, in which the emission colour or intensity changes reversibly in response to external mechanical force or pressure.
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Proteomics in tissue regeneration: insights into protein alterations and post-translational modifications during healing

J. Mater. Chem. B, 2026, 14,3932-3946
DOI: 10.1039/D5TB02812D, Review Article

Sarad Pawar Naik Bukke, Chandrashekar Thalluri, Jharna Medhi, Mallikarjun Vasam, Neha Gupta, Piyali Dey, Milon Selvam Dennison, Muhamad Mustafa Mundu
Proteomic profiling reveals dynamic protein expression and post-translational modifications regulating wound healing and tissue regeneration, controlling cell proliferation, stem cell activation, and signaling pathways.
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Antimicrobial cotton fabrics modified with a cationic perylene diimide derivative for durable and superior sterilization

J. Mater. Chem. B, 2026, 14,4070-4079
DOI: 10.1039/D5TB02871J, Paper

Jia Yin, Yuanyuan Zhu, Meiqi Li, Yuxin Ren, Yuze Wang, Wenhua Jia, Jiaying Miao, Ling Li, Yanli Tang
We successfully construct antimicrobial cotton fabrics OCF-PDA-PDI, which could eliminate bacteria through synergistic contact-killing and photodynamic sterilization. Meanwhile, it demonstrated exceptional wash-durable antimicrobial performance.
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Construction of soluble sufentanil microneedles and their analgesic effects in a mouse model of cancer pain

J. Mater. Chem. B, 2026, 14,4098-4112
DOI: 10.1039/D5TB02821C, Paper

Ayang Zhao, Yueyue Gao, Ao Zhang, Yuting Rong, Guibo Fan, Rui Xin, Sixun Chen, Liangcan He, Sihua Qi
A soluble sufentanil microneedle patch enables rapid transdermal delivery and effective cancer pain relief.
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BSA-mediated proton-coupled electron transfer to unlock the photogeneration of hydroxyl radicals in cancer cells

J. Mater. Chem. B, 2026, 14,4113-4124
DOI: 10.1039/D5TB02650D, Paper

Guiyan Xu, Yingyong Ni, Xiaojiao Zhu, Xuan Zhao, Ting Wang, Shengyu Shi, Jianhua Yu, Qiong Zhang, Xingxing Chen, Hongping Zhou
The subdomain IIA of BSA encapsulates TC2via multiple interactions and mediates proton-coupled electron transfer (PCET) to enable the photogeneration of ˙OH in cancer cells.
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Sustained copper-releasing adhesive hydrogel patch promotes optimized scarless tongue wound healing via antioxidative, angiogenic and antifibrotic synergy

J. Mater. Chem. B, 2026, 14,4018-4036
DOI: 10.1039/D5TB02753E, Paper

Yutang Ding, Kun Tang, Yuheng Zhang, Linxin Yang, Binjing Zhang, Xin Zhang, Jian Wang
The CPTCu patch, tailored for tongue wound applications, provides dynamic wound protection while reducing scarring and enhancing vascular and muscular regeneration.
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Advances in Ultrasensitive Detection Technologies for Blood-Based Biomarkers of Alzheimer's Disease

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02633D, Review Article

Yu Mou, Chenwei Sun, Ke Deng, Fulin Lin, Zehong Yang, Yulin Wang, Xueling Deng, Fan Yang, Xuefeng Hu, Qing Jiang
Current diagnostic approaches for Alzheimer's disease (AD), including neuroimaging and cerebrospinal fluid (CSF) analysis, are limited by their invasiveness, high cost, and restricted accessibility. In contrast, ultrasensitive blood-based assays overcome...
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A nanoscale cascade system integrating calcium interference with phototherapy–chemotherapy synergy for enhanced antitumor efficacy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00308G, Paper

Haiyu Shen, Ying Gao, Tingting Wang, Rongrong Zhang, Lu Li, Lingyu Zhang, Chungang Wang, Xiangting Dong
A PB@PAA-CaO₂@PDA platform integrating calcium release, drug loading, and photothermal conversion was facilely constructed, enabling efficient antitumor efficacy through synergistic calcium overload/photothermal/chemotherapy.
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Skeletal muscle tissue engineering using magnetic nanoparticles: a comprehensive review

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02777B, Review Article

Open Access

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Nipun Jain, Sudipto Datta, Prerana Singh, Dileep Pathote, Samir Das, Ranjit Barua, Darren Player
Skeletal muscle tissue engineering (SMTE) is a promising tissue therapy that can innovatively address the challenges arising from trauma, diseases, or congenital disabilities.
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Natural Polyphenol-Taurine based Nanoparticles for Oral Ulcer Therapy

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02719E, Paper

Xun Pan, Hengjie Zhang, Jinling Zhao, Zhipeng Gu, Huixu Xie, Jian Wang
Oral ulcers are the most common self-limiting diseases of the oral mucosa and the pathogenes is caused by local overload of reactive oxygen species (ROS) that precipitates tissue breakdown, which...
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Glutathione-responsive conjugates of hyperbranched poly-oxidized glutathione and camptothecin for cancer therapy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00449K, Paper

Qiang Wang, Wenqian Qian, Boxu Liang, Xianghuang Mei, Yuchao Lu, Wei Guo, Xiao Duan
This paper developed a nanomedicine with oxidized glutathione as a carrier for simultaneously addressing the problems of biocompatibility, biodegradability and drug control release in the drug delivery field.
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Tailored surface functionalization of AlN nanotubes for 5-fluorouracil adsorption and encapsulation: a first-principles and molecular dynamics study

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02632F, Paper

Open Access

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V. Abinaya, K. Janani Sivasankar, J. Sneha, K. S. Bharath Shirpi Thasan, K. Iyakutti, D. John Thiruvadigal
The rational design of biocompatible nanocarriers is essential for improving the efficacy and safety of anticancer therapeutics.
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Water-soluble acylhydrazone macrocycles as potent reversal agents for cisatracurium-induced neuromuscular blockade

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02867A, Paper

Open Access

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Yongfei Yin, Yangyang Ge, Qian Li, Yi Chen, Siyuan Zhou, He Deng, Shigui Chen, Yun Lin, Lu Wang
A water-soluble acylhydrazone macrocycle with an electron-rich cavity efficiently binds cisatracurium and reverses neuromuscular blockade in vivo as a supramolecular antidote.
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Interpenetrating polymer network hydrogels with EGCG-MPN and nitric oxide for periodontitis

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02717A, Paper

Jingwen Yu, Jingjing Tang, Jiahui Li, Wei-Hua Peng, Guanhai Wang, Xiaozhi Lv
A low-swelling IPN hydrogel enables pH-responsive and diffusion-controlled release of NO/EGCG to effectively eliminate bacteria and promote periodontal tissue regeneration.
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Hen egg lysozyme fibrils act as amyloid nucleating agents for β-lactoglobulin and insulin

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB01615K, Paper

Kailash Prasad Prajapati, Pranjali Yadav, Shikha Mittal, Masihuzzaman Ansari, Prashantkumar Parmar, Aurgha Kamal Bhandari, Bibin Gnanadhason Anand, Karunakar Kar
Understanding the mechanism of the amyloid cross-seeding/coaggregation process has become fundamentally important for deciphering the molecular mechanism of the progression of amyloid-associated diseases.
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Polymeric quaternary ammonium enabled contact-active, bulk-stable and biocompatible antibacterial catheters for overcoming leaching-dependent antimicrobial additives

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02938D, Paper

Yicheng Li, Ruyi Jiang, Shuai Gao, Bingran Yu, Dimeng Wu, Shun Duan, Fujian Xu
Catheter-associated infections remain a major clinical challenge due to microbial colonization on medical plastics. Conventional strategies using small-molecule antibacterial additives or surface coatings often suffer from rapid leaching, limited durability,...
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Fabrication of near-infrared-light-responsive photothermal tea leaf-derived particles with thermotolerance inhibitory and anticancer activities

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00055J, Paper

Open Access

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Keito Suzuki, Syuuhei Komatsu, Kanae Ishii, Kaho Tanaka, Yuka Kiba, Masashi Kitamua, Toru Kimura, Ryuichiro Suzuki, Takashi Tanikawa, Kazuya Oki, Atsushi Takahashi, Hiroaki Todo
TLNPs-ICG combines NIR photothermal heating, EGCG-mediated anticancer activity, and HSP70/90 suppression in a plant-derived nanoplatform, enhancing repeated mild photothermal therapy and improving antitumor efficacy against melanoma.
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Fibroin/sulfated alginate membranes containing exosomes of stem cells treated with B and Zn-doped hydroxyapatite for periosteal tissue engineering

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02784E, Paper

Open Access

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Sema Akbaba, Senem Ozge Turacli Karaguven, Zafer Evis, Ayşen Tezcaner
Hydroxyapatite-preconditioned stem cells produce exosomes with an altered cargo that modulate osteogenic and inflammatory responses when delivered via periosteum-mimetic fibroin/sulfated alginate membranes.
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MoS2 phase transition-assisted sensitive detection of cholesterol on a copper oxide@molybdenum disulfide nanocomposite

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02549D, Paper

Haritha Kuttoth, Resmi V. Nair, N. Sandhyarani
A highly sensitive and selective electrochemical sensor for cholesterol is developed using CuO@MoS₂ nanocomposite that leverages the peroxidase-like properties of MoS₂ and the strong catalytic effect of CuO to enhance cholesterol oxidation, achieving detection up to 400 mg/dL in whole blood.
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Antibacterial porous polycaprolactone films via rapid spontaneous spreading

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02563J, Paper

Tianbao Li, Qiaohua Qiu
In this study, we describe an ultrafast and simple process for forming polycaprolactone (PCL) porous films on an aqueous substrate within seconds via spontaneous spreading (SS). The process is driven...
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Magnetoelectric biodegradable uniform composite microactuators for biomedical applications

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02857D, Communication

Tatiana N. Pallaeva, Sergey A. Lisitsyn, Alexandra M. Gordeeva, Arkady S. Abdurashitov, Abdulkarim A. Amirov, Olesya Lutsenko, Pavel I. Proshin, Marina B. Sharapova, Alexander V. Romashchenko, Gleb B. Sukhorukov
Biodegradable microactuators with a magnetoelectric effect fabricated via a template-based method using poly-L-lactic acid and magnetic nanorods for remote electrical stimulation.
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A CSA-catalyzed strategy for constructing 1H-pyrazolo[4,3-f]quinoline-8-carboxamide scaffolds as antimicrobial agents

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02769A, Paper

Neel D. Javiya, Disha P. Vala, Mehul P. Parmar, Anjali S. Bhut, Sanjukta Roy, Shana Balachandran, Rambabu Dandela, Madan Kumar Arumugam, Hitendra M. Patel
CSA-mediated green synthesis of pyrazolo[4,3-f]quinolines in ethanol shows high atom economy and low E-factor with gram-scale feasibility. The compounds exhibit promising antimicrobial and anticancer activity.
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Synergistic mechanochemical regulation in PNIPAM/tannic acid hydrogels for enhanced diabetic wound healing

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02657A, Paper

Huiying Wu, Qianwen Zhang, Jiayi Dang, Qida Zong, Bo Fu, Chun Liu, Wei Sun, Yinglei Zhai
A multifunctional hydrogel (PGA-TA) with antioxidant and thermoresponsive contraction properties was synthesized. N-Isopropylacrylamide and acrylic acid were copolymerized with guar gum via redox-initiated polymerization to form a semi-interpenetrating network, followed by tannic acid incorporation.
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Plasmonic Hot-Electron-Assisted Ultra-Stretchable Hydrogel Electrodes for Wearable Cardiovascular Monitoring and AI-Driven Predictive Analytics

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D5TB02743H, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Bangul khan, Syed Bilal Ahmed, Bilawal Khan, Muhammad Shehzad Khan, Liangyi Lyu, Iyapan Gunasekran, Rafi-u-Shan Ahmad, Junchen Liao, Mohammad E Hosseini, Bee Luan Khoo
Wearable bioelectronics require materials that combine high conductivity, mechanical resilience, and biocompatibility, traits rarely achieved together. We report a plasmonic hotelectron-assisted conductive hydrogel (Ag-PEDOT: PSS-PAM) engineered for continuous wearable cardiovascular...
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Recent Advances in Carbohydrate Polymers-Supported Composites for Monitoring Breast Cancer Biomarkers: A Comprehensive Review

J. Mater. Chem. B, 2026, Accepted Manuscript
DOI: 10.1039/D6TB00002A, Review Article

Yuting Qiao, Huijie Hou
Breast cancer (BC) remains one of the leading causes of cancer-related mortality among women worldwide. The development of highly sensitive and selective biosensors for the accurate detection of BC biomarkers...
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Porous organic polymers based on deep-cavity calixarenes for broad-spectrum and high-affinity drug adsorption in the gastrointestinal tract

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02700D, Paper

Wei-Yan Chen, Xiao-Min Cao, An-Kang Ying, Yuan-Qiu Cheng, Shu-Xin Zhang, Han-Fei Fu, Yue Li, Dong-Sheng Guo
A series of calixarene-based porous organic polymers were developed for gastrointestinal detoxificationachieved through a longitudinally extended calixarene cavity that provides high-affinity and selective drug adsorption.
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Antibacterial peptide microspheres and recombinant human type XVII collagen (rhCXVII) modified protein hydrogels for synergistically combating dental caries

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D6TB00100A, Paper

Ting Zheng, Qiaoyue Ren, Hang Chen, Xinlei Zhao, Yujia Xie, Ding Xiong, Yang Yao, Zhenming Wang, Yu Shi
This study presents an enzymatically crosslinked hydrogel (C17/PL-CA-H) that combines antibacterial poly-L-lysine microspheres with C17.
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Amorphous calcium pyrophosphate bone cement sets without crystallization: a physico-chemical and in vitro biological study

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02873F, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

L. Touati, M. Y. Hammami, C. Damia, M. Renard, D. Bertrand, M. Durand, J. Amédée, C. Bonhomme, C. Combes
An original amorphous calcium pyrophosphate cement sets without crystallization.
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Biological effect of silver nanowires in biomedical applications

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02604K, Review Article

Xueqian Li, Xuetao Shi, Feng Li, Yuzhu Kong, Yidan Wang, Tian Bai, Mi Chen, Wenhao Zhou
Silver nanowires show significant promise in diverse biomedical applications including orthopedics, skin wound repair, tumor therapy, wearable devices, skeletal muscle, and nerve repair.
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Harmonizing the adhesion–release dilemma: a bio-based injectable hypertonic hydrogel for bladder perfusion therapy

J. Mater. Chem. B, 2026, Advance Article
DOI: 10.1039/D5TB02530C, Paper

Lihang Jiang, Yuhang Li, Wenjing Liu, Shuai Wu, Shuangying Tang, Dong Wen, Huili Yuan, Dahong Zhang, Si Chen, Xu Wang
The high incidence of bladder diseases significantly impairs patients’ quality of life, and there is an urgent need for improved local treatment strategies for superficial bladder cancer.
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Synthesis and characterization of an injectable telechelic material for the epiretinal delivery of retinal gene therapies

J. Mater. Chem. B, 2026, 14,3703-3718
DOI: 10.1039/D6TB00267F, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

James H. Westbay, Daniel P. Bigley, Sushma Sappa, Anfisa Ayalon, Hamzah Aweidah, Lauren D. Dignam, Joseph N. Martel, William A. Beltran, José-Alain Sahel, Leah C. Byrne, Morgan V. DiLeo
There is a need to develop safer, more efficient, and targeted strategies for the delivery of retinal gene therapies.
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